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Engineered phage-derived lysins effectively kill mycobacterial pathogens

Antimicrobial resistance in pathogenic mycobacteria remains a critical challenge due to poor drug penetration through their complex cell wall, which necessitates prolonged multidrug regimens. Mycobacteriophages encode a lytic machinery that can disrupt this barrier. In this research article, we describe a modular mycolysin platform combining phage enzymes Lysin A and Lysin B with outer membrane-pe

Water and counterion structuring around cyclic anionic surfactant micelles in solution

Wide-angle neutron scattering analysed using empirical potential structure refinement (EPSR) was used to investigate how aromatic ring structure influences micelle self-assembly in two anionic surfactants: sodium 4-heptylbenzene sulfonate (SHBS) and sodium 5-heptylfuran-2-sulfonate (SHFS). Both surfactants formed globular micelles in aqueous solutions at 0.2 M but differed significantly in micelle

Pneumococcal serotype epidemiology and resistance after PCV13 replacement with PCV10, Sweden

Objectives: To evaluate the impact of the 2018 switch from PCV13 to PCV10 in Sweden’s childhood immunisation programme on the serotype distribution of Streptococcus pneumoniae.MethodsRespiratory tract (RT) S. pneumoniae isolates (n=1615; 2020–2023) were serotyped, tested for antimicrobial susceptibility and compared with invasive pneumococcal disease (IPD) isolates (n=397) and PCV13-era data (2016

Exact Stoichiometry Far-Off Neutrality Catanionic Nanotubes : Unconventional Self-Assembly of Oppositely Charged Surfactants

Electrostatic energy plays a pivotal role in the minimization of the free energy of self-assembling oppositely charged ions. This is a fundamental principle that guides the formation of aggregates and the separation of phases characterized by a stoichiometric balance between the opposite charges. However, this study unveils the self-assembly of catanionic nanotubes from a mixture of oppositely cha

Development and application of a wipe sampling method for detection of antibiotic surface contamination in hospital wards

BackgroundAntibiotics are handled in large amounts at hospitals at many different wards due to the wide range of bacterial infections that are treated. Unnecessary use and occupational exposure to antibiotics should be avoided due to the risk of bacterial resistance development and adverse health effects including skin and respiratory hypersensitivity reactions in persons handling these drugs.Obje

Immunosuppressants for IgG4-related disease

OBJECTIVES: This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits and harms of immunosuppressants with or without corticosteroids compared to corticosteroid monotherapy for the treatment of IgG4-related disease in people 18 years or older.

Investeringsrådgivning - bankernas skyldigheter

Finansmarknaden genomgick stora förändringar innan 2000-talet och placeringsrådgivning kom att spela en allt viktigare roll. Tidigare hade det inte funnits lagstiftning på området, vilket man nu införde. Först kom Lag (2003:862) om finansiell rådgivning till konsumenter (FRL), därefter utfärdades ett EG-direktiv. Direktivet införlivades i svensk rätt genom Lag (2007:528) om värdepappersmarknaden (The Financial Market went through significant changes before the 2000’s and investments advisory played an increasingly important role. Earlier there had not been any legislation on the subject which there is now. The first legislation was the act of financial advisory and after that the Markets in Financial Instruments Directive, MiFID came from the EU. MiFID was implemented into Swedish law thro

Will the electrical grid sustain the change towards an electrified freight truck fleet?

Med en elektrifiering av tunga lastbilar kommer elbehovet att ̈oka kraftigt och elnätet ̈ar inte förberedd p ̊a utmaningen. Det rader kapacitetsbrist i nätet och det behöver utredas hur den kan undvikas. Transportsektorn star infor stora förändringar för att minska sitt klimatavtyck. Elnätet ̈ar en kritisk infrastruktur för att möjliggöra denna omställning. Förutom att bygga ut finns det m ̈ojlighThe transport sector is facing major challenges to reduce the greenhouse gas emissions. The electrification of the freight fleet, which is an important step towards emission reduction, will result in capacity challenges in the grid. The aim of this thesis is to evaluate how the existing grid is affected by the electrification of heavy trucks and what solutions or reinforcements needs to be impleme

Immune challenge reduces daily activity period in free-living birds for three weeks

Non-lethal infections are common in free-living animals and the associated sickness behaviours can impact crucial life-history trade-offs. However, little is known about the duration and extent of such sickness behaviours in free-living animals, and consequently how they affect life-history decisions. Here, free-living Eurasian blackbirds, Turdus merula, were immune-challenged with lipopolysacchar

Samtal som metod - En studie om samtalsgrupper som utvecklingsmetod i en svensk skolkontext

I föreliggande psykologexamensuppsats kombinerades kvalitativa och kvantitativa metoder i syfte att explorativt undersöka innehållet i pedagogers samtalsgrupper samt för att utforska samtalsledarens roll. Studien utformades i samråd med utbildningsförvaltningen i den studerade kommunen. Åtta samtalsgrupper deltog i en observationsundersökning. Ett strukturerat observationsschema, IPA, användes förIn the presented Master’s Thesis qualitative and quantitative methods were combined in order to, with an explorative approach, examine the content of the Teacher Learning Communities (TLC) and to examine the role of the facilitator. The study was developed in agreement with the Department of Education in the participating municipality. Eight TLCs were observed. A structured observation chart, IPA,

2022

Artiklar Algård, A. & Arvidsson, N. (2022) Skadeståndsansvar för juridisk rådgivning. I: Svensk Juristtidning. Arvidsson, N. & Adestam, J. (2022). Avtalsrättsligt medhjälparansvar. I: Svensk Juristtidning. 2022, 1, s. 98-123 Arvidsson, N. (2022). Aktieägaravtal i ett processuellt perspektiv - särskilt om skiljedomsmässighet i kontexten av tvingande regler. I: Juridisk tidskrift vid Stockholms Univ

https://www.aclu.lu.se/publikationer/annat-publicerat/2022 - 2026-05-19

Stark autentisering

Lunds universitet tar nästa steg för en säkrare IT-miljö. För att skydda universitetet mot den ökade hotbilden som finns i dag, räcker det inte med bara säkra lösenord, utan det krävs även stark autentisering för inloggning i universitetets IT-tjänster. För närvarande gäller detta enbart medarbetare på Lunds universitet, inte studenter.Stark autentisering är ett sätt att logga in som gör det svåra

https://www.medarbetarwebben.lu.se/stod-och-verktyg/it-e-post-post-och-telefoni/stark-autentisering - 2026-05-20

2011 duvbibliotek

FOLDER 3 Universitetsbibliotekets utställningskatalog 63 28 Universitetsbiblioteket, Lunds universitet Box 3, 221 00 LUND UB Media. ISSN 0281-3823, LULID/LIBR - 1551 9 december 2011 - 22 april 2012 Universitetsbiblioteket i Lund fick 2007 ta emot en säll- sam och ovanligt spännande donation från Berit Harrison i Klörup. Hennes make direktör Bertil Harrison köpte redan som 10-åring sin första bok o

https://www.ub.lu.se/en/sites/ub.lu.se.en/files/2011_duvbibliotek.pdf - 2026-05-20

Erik Wengström

Studierektor forskarutbildningen, Nationalekonomiska institutionen, Professor Kontaktinformation E-post: erik [dot] wengstrom [at] nek [dot] lu [dot] se Telefon: +46 46 222 01 23Organisation Nationalekonomiska institutionen Rumsnummer: Alfa1:4091A Hämtställe: 10 WebbplatsErik Wengströms profil i Lunds universitets forskningsportalPersonlig webbplats:https://sites.google.com/site/erikwengstromAndra

https://www.ehl.lu.se/erik-wengstrom - 2026-05-20

The specific organism : Not bacterial gram type: Drives the inflammatory response in septic shock

Background and Hypothesis: The inflammatory response was targeted by unsuccessful therapies but ignored pathogen. We hypothesized that the inflammatory response differs according to organism in human septic shock. Materials and Methods: We measured 39 cytokines at baseline and 24 h in patients (n = 363) in the Vasopressin and Septic Shock Trial (VASST). We compared cytokine profiles (cytokine func

Microsoft Word - OtydligaMaal_V101_utankomm.doc

Microsoft Word - OtydligaMaal_V101_utankomm.doc LTHs 10:e Pedagogiska Inspirationskonferens, 6 december 2018 Sammanfattning—CEQ-resultaten för en del projektbase- rade kurser visar att studenterna upplever att kursens mål inte är tydliga (skalan ”Tydliga mål”, TM, i CEQ). Studenterna verkar således vara ganska osäkra på vad lärarna förväntar sig av dem. Detta är ett problem som kräver uppmärksamh

https://www.lth.se/fileadmin/lth/genombrottet/konferens2018/D5_Motte_etal.pdf - 2026-05-19

Partitioned methods for time-dependent thermal fluid-structure interaction

The invention of computers revolutionized the way of doing science and in particular the field of mathematics. Computers were faster than any human mind in doing calculations and they did not make mistakes opening a wide range of possibilities that earlier where in practice uncomputable. Scientists observe the behavior of nature and find mathematical equations that model the different phenomena. IThe efficient simulation of thermal interaction between fluids and structures is crucial in the design of many industrial products, e.g. turbine blades or rocket nozzles. The main goal of this work is to present a high order time adaptive multirate parallel partitioned coupled method for the efficient numerical solution of two parabolic problems with strong jumps in the material coefficients that

In the wake of a bird - Quantifying aerodynamic performance of avian flight

Popular Abstract in English Insects, birds, bats and pterosaurs have all evolved the ability to fly, even though it requires a lot of energy. The advantage is obvious: one can move about vertically, to go where others cannot, find and access distant food sources or escape your predators. But flying is also a very fast mode of transportation, and when you count the amount of energy required to get Flight is an expensive form of locomotion, but also offers the ability to travel great distances at relatively low cost. Birds have developed various adaptations for optimizing flight performance. The main aim of this thesis is to identify how morphological variables in birds affect aerodynamic drag and flight performance. To this end I studied the aerodynamic performance of a jackdaw (Corvus mone