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Background: Subgroups of adult-onset diabetes, namely severe autoimmune diabetes (SAID), severe insulin-deficient diabetes (SIDD), severe insulin-resistant diabetes (SIRD), and mild obesity-related diabetes (MOD) or mild age-related (MARD) diabetes, have been defined with clinical variables and a machine-learning approach. Our aim was to describe their long-term outcomes and mortality. Methods: In
Disorder is an intrinsic feature of all solids, from crystals of atoms to superlattices of colloidal nanoparticles. Unlike atomic crystals, in nanocrystal superlattices, a single misplaced particle can affect the positions of neighbors over long distances, leading to cumulative disorder. This elusive form of collective particle displacement leaves clear signatures in diffraction, but little i
Adjustable magnetic field sources have become indispensable in advanced material characterization techniques. Among these, permanent magnet assemblies offer significant advantages by reducing power consumption and minimizing Joule heating. In this work, we report on the development and integration of a tunable magnetic sample environment at the SoftiMAX beamline of the MAX IV synchrotron, employin
A workshop entitled "Stem Cells, Cell Therapies and Bioengineering in Lung Biology and Diseases" was hosted by the University of Vermont Larner College of Medicine in collaboration with the National Heart, Lung and Blood Institute, the Alpha-1 Foundation, the Cystic Fibrosis Foundation, the International Society for Cell and Gene Therapy and the Pulmonary Fibrosis Foundation. The event was held fr
Objectives To estimate the risk of clinically diagnosed knee osteoarthritis (OA) after different types of knee injuries in young adults. Methods In a longitudinal cohort study based on population-based healthcare data from Skåne, Sweden, we included all persons aged 25-34 years in 1998-2007 (n=149 288) with and without diagnoses of knee injuries according to International Classification of Disease
Objective: IgG antibodies against apolipoprotein A-I (ApoA-I) have been found to be elevated in subjects from the general population with clinically manifest cardiovascular disease and in myocardial infarction patients with an adverse prognosis. Here, we investigated whether these antibodies are prospectively associated with carotid artery disease progression and with the risk for first-time cardi
Objective: To estimate the association between molecular or imaging inflammatory biomarkers at 2 years after anterior cruciate ligament (ACL) injury and patient-reported outcomes at 5 years. Methods: For 116 ACL-injured patients, molecular biomarkers of inflammation (synovial fluid and serum cytokines) and Hoffa- and effusion-synovitis as visualized on magnetic resonance imaging (MRI) were assesse
Background: Aortic stenosis (AS) is the most common valvular heart disease in developed countries, confers high mortality in advanced cases, but can effectively be reversed using endovascular or open-heart surgery. We evaluated the association between AS and neighborhood socioeconomic status (NSES). Methods: We used Swedish population-based nationwide registers and an echocardiography screening co
Rationale: Proinflammatory cytokines have been identified as potential targets for lowering vascular risk. Experimental evidence and Mendelian randomization suggest a role of MCP-1 (monocyte chemoattractant protein-1) in atherosclerosis and stroke. However, data from large-scale observational studies are lacking. Objective: To determine whether circulating levels of MCP-1 are associated with risk
OBJECTIVES: Primary graft dysfunction is a severe form of acute lung injury and a major cause of early morbidity and mortality encountered after lung transplant.We used a customized PExA 2.0 instrument (PExA, Gothenburg, Sweden) to measure particle flow in exhaled air during mechanical ventilation in the intensive care unit. Our objective was to discover whether patients who developed primary graf
Background and Purpose- Extracellular matrix proteins are important in atherosclerotic disease by influencing plaque stability and cellular behavior but also by regulating inflammation. COMP (cartilage oligomeric matrix protein) is present in healthy human arteries and expressed by smooth muscle cells. A recent study showed that transplantation of COMP-deficient bone marrow to apoE-/- mice increas
The role of CD4+ T cells in atherosclerosis has been shown to be dependent on cytokine cues that regulate lineage commitment into mature T helper sub-sets. In this study, we tested the roles of IL-1R1 and MyD88 signalling in CD4+ T cells in atherosclerosis. Methods and results We transferred apoe-/-myd88\+/\+ or apoe-/-myd88-/- CD4+ T cells to T-A nd B-cell-deficient rag1-/-apoe-/- mice fed high f
The ability to capture alterations in the genome or transcriptome by next-generation sequencing has provided critical insight into molecular changes and programs underlying cancer biology. With the rapid technological development in single-cell sequencing, it has become possible to study individual cells at the transcriptional, genetic, epigenetic, and protein level. Using single-cell analysis, an
Objectives: To study bone shape changes as a potential early feature of post-traumatic structural knee OA development, we estimated the association between meniscal status in the anterior cruciate ligament (ACL) injured knee and longitudinal condyle changes in bone surface area. Design: We used data from the KANON trial, including 121 young ACL-injured adults. We obtained baseline and 2-year follo
Cancer cells display marked heterogeneity in size and morphology, traits long recognized in pathology as indicators of pleomorphism and poor prognosis. Yet, the functional significance and phenotypic consequences of these morphological variations within a single cancer cell population remain poorly understood. Here, we employed a deterministic lateral displacement (DLD) microfluidic device with a
Registrera timmar och OB-tillägg vid intermittent anställning Registrera timmar För att kunna logga in i Primula behöver du en LUCAT-inloggning. Du får en engångskod för kontoaktivering av katalogadministratören på din institution, antingen utskrivet eller via mail. Se länk till lathund för kontoaktivering. https://lucat.blogg.lu.se/files/2015/09/Aktivera-ett-nytt-konto.pdf Gå in på Medarbetarwebb
https://www.cgbkansli.lu.se/sites/cgbkansli.lu.se/files/n-fak_manual_registrera_timmar_och_ob.pdf - 2026-07-19
Kursguide - Course Syllabus • • • Fastställande Kursplanen är fastställd av Naturvetenskapliga fakultetens utbildningsnämnd 2014-10-29 att gälla från och med 2014-10-29, höstterminen 2014. Allmänna uppgifter Kursen ingår i huvudområdet geologi vid den naturvetenskapliga fakulteten. Kursen är en valbar kurs på grundnivå för en naturvetenskaplig kandidatexamen i geologi. Kursen ges även som friståen
https://www.geologi.lu.se/sites/geologi.lu.se/files/geob12-kursplan.pdf - 2026-07-19
Brevmall Instructions for course syllabi at the Faculty of Social Sciences The information below describes the minimum requirements for the content of all course syllabi drawn up at the Faculty of Social Sciences. The instructions are based on the Swedish Higher Education Ordinance (HF), the implementation regulations for course and programme syllabi at Lund University (SU2012/244), the local rule
