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Brain-derived neurotrophic factor (BDNF) and other neurotrophins are believed to play an important role in affective disorders. In this study we investigated plasma-BDNF response during an incremental exercise test in 18 patients suffering from moderate major depressive disorder (MDD) and 18 controls. The patients were not treated with antidepressants or neuroleptics. Possible associations between
PURPOSE: The early loss of a parent is a tragedy and a serious life event. This study investigated grief resolution and morbidity in cancer-bereaved teenagers 6 to 9 years after the loss of a parent to cancer. METHODS: In a nationwide population-based study of 622 of 851 (73 %) youths who as teenagers 6 to 9 years earlier had lost a parent to cancer, we explored the magnitude of unresolved grief a
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Customer service plays an important role for the competitive strength in the market place. Customer service is however also a concern on the supply side of the company in the sense that assessing, selecting and developing suppliers to improve their customer service can make them contributing to the competitiveness of the company. It is from the latter perspective that this research has been carrie
Abstract in UndeterminedThe success of the Wii and of the iPhone together with the persisting problem of displaying information on the small screens of mobile devices is currently pushing the development of non-visual interaction channels such as gestures, tactile/haptic interaction and sound. This development presents both potential and risk, since new channels of interaction may result either in
Programmes driving ELT design are discussed. The nature and evolution of circum-stellar shells and planetary discs are attractive, while the small angular sizes place basic properties, asymmetry and warps, beyond VLT capability. An ELT is neeed to reveal the conversion processes shell - disc - planets, planetary systems, Earth-like planets, habitability and life signatures. Formation and evolution
Popular Abstract in Swedish Avhandlingens ämne är den mezuzah, en kapsel med texter ur 5 Mosebok, som bör fästas på dörrposterna i ett judiskt hem, i uppfyllande av budet i 5 Mos. 6:9/11:21: "och du skall skriva dem [dessa ord] på dörrposterna i ditt hus och på dina portar". Genom en översikt över rabbinska texter vilka behandlar budet att fästa en mezuzah på dörrposterna i hemmet inThe present study deals with different aspects of the mitsvat mezuzah in Rabbinic literature from the first to the sixteenth centuries, with some emphasis on the medieval sources. Through a charting of statements regarding the mezuzah as an object, and the mitsvat mezuzah and its fulfilment, an overview is given of the development of the mezuzah and the perception of it
The article uses embodiment and the experiential basis of conceptual metaphor to argue for the metaphorical essence of abstract legal thought. Abstract concepts like ‘law’ and ‘justice’ need to borrow from a spatial, bodily, or physical prototype in order to be conceptualised, seen, for example, in the fact that justice preferably is found ‘under’ law. Three conceptual categories of how law is con
A machine-learning and a string-matching approach to automated subject classification of text were compared, as to their performance, advantages and downsides. The former approach was based on an SVM algorithm, while the latter comprised string-matching between a controlled vocabulary and words in the text to be classified. Data collection consisted of a subset from Compendex, classified into six
The purpose of this study was to investigate illness experiences of patients after a first myocardial infarction (MI), focusing on life situation and the recovery process over time. Thirty patients were interviewed within the first 3 days of hospitalisation, and again 17 weeks after discharge. The interviews were tape-recorded verbatim and the transcriptions were analysed and categorised using qua
The rd1 mouse is a relevant model for studying the mechanisms of photoreceptor degeneration in retinitis pigmentosa. Treatment with ciliary neurotrophic factor (CNTF) in combination with brain derived neurotrophic factor (BDNF) is known to rescue photoreceptors in cultured rd1 retinal explants. To shed light on the underlying mechanisms, we studied the effects of 9 days (starting at postnatal day
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In search for remedies and treatments, science has recurred to Mother Nature. This is where galiellalactone was found, a fungal metabolite isolated from Galiella rufa in 1990. Since then chemists and biologists have been studying its properties and found it to be a potential candidate against castration-resistance prostate cancer (CRPC). The development of a new drug requires many studies of the c
