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AbstractObjective: This article presents a summary of the 2025 Swedish prostate cancer guidelines, focusing on recurrence after local treatment, metastatic disease, and castration-resistant prostate cancer.Results: The 2025 Swedish guidelines introduce several important updates. Prostate specific membrane antigen (PSMA)-PET/CT is recommended only when PSA exceeds 0.2 µg/L, and reporting should fol
Biological neural network functionality depends on the vast number of connections between nodes, which can be challenging to implement artificially. One radical solution is to replace physical wiring with broadcasting of signals between the artificial neurons. We explore an implementation of this concept by light emitting/receiving III-V semiconductor nanowire neurons in a quasi-2D waveguide. They
This paper presents an initial technology assessment of the suitability of using aluminium as an energy carrier in shipping. The overall conclusion is that aluminium may become a suitable future energy carrier. Several advantages of using aluminium exist, including high theoretical energy densities, high resource availability, opportunity for circularity, and future potential for low lifecycle env
Due to the threat climate change poses, the aviation industry needs to adapt. In the process to convert the aviation fleet into a more environmentally friendly fleet, using biofuels such as Sustainable Aviation Fuels as a drop-in fuel remains a promising option. To include biofuels, safety aspects need to be investigated, where combustion instabilities are important. Thermo-acoustic instabilities
This study presents high-fidelity Large Eddy Simulations (LES) of supersonic combustion in a Mach 2 cavity flameholder over the full stable fueling region from 40 to 200 slpm. The simulations employ Finite Rate Chemistry LES with the Z70 ethylene-air mechanism, the Localized Dynamic k-equation model, Partially Stirred Reactor turbulence-chemistry interaction model, conjugate heat transfer, and the
The Sandvik Group is a world leading company and their unique competence in materials technology has resulted in three core areas; Cutting Tools, Mining and Construction and Materials Technology (SMT). This thesis has been initiated by their third business area, SMT, who is looking into the possibility to enter a new industry by offering superior material solutions. The industry is the musical ins
Prior to resettlement, refugee children are exposed to stressors that leave them vulnerable to the development of health and psychosocial problems. The nature of these problems has been identified in numerous studies involving refugee children and their parents, yet relatively few studies have been carried out with workers from governmental and voluntary organizations. The primary aim of this stud
Grassroots innovations are seen as important contributors to sustainability transitions, however, given their dependence on place-specific conditions they face diffusion challenges. Responding to previously outlined gaps regarding conceptualisation and exploration of the spatiality of grassroots innovations, this paper introduces a conceptualisation of nomadic grassroots innovations. These are gra
Effectively identifying deviations in real-world medical time-series data is a critical endeavor, essential for early surveillance of disease outbreaks. This paper demonstrates the integration of time-series anomaly detection techniques to develop surveillance systems for disease outbreaks. Utilizing data from Sweden's telephone counseling service (1177), we first illustrate the trends in physical
The aim of this work is to investigate the presence of airborne SARS-CoV-2 in corridors of infection wards, and gain more detailed size information of SARS-CoV-2-containing aerosols. Associations between SARS-CoV-2 presence and relative humidity and/or temperature in the facilities is also explored.
Despite incredible progress in cancer treatment, therapy resistance remains the leading limiting factor for long-term survival. During drug treatment, several genes are transcriptionally upregulated to mediate drug tolerance. Using highly variable genes and pharmacogenomic data for acute myeloid leukemia (AML), we developed a drug sensitivity prediction model for the receptor tyrosine kinase inhib
Ethicisation refers to the tendency to frame issues in ethical terms and can be observed in different areas of society, particularly in relation to policy-making on emerging technologies. The turn to ethics implies increased use of ethics expertise, or at least an expectation that this is the case. Calling for experts on ethics when ethically complicated questions need to be handled helps us to up
Grandparents’ involvement in their adult children’s everyday family life seems to have increased, especially in relation to care arrangements around grandchildren (Arber & Timonen 2012; May et al., 2012; Cantillon et al., 2021). This is the case also in Sweden, despite extensive public welfare provision of childcare (Hank & Buber, 2009; Björnberg & Ekbrand, 2008). This “new army of pro
We are reporting an efficient, label-free and continuous separation of mononuclear cells (MNC), from blood using microchip acoustophoresis. In standard PBS buffer, MNCs and red blood cells (RBC) display overlapping acoustophoretic mobilities which compromise separation of these cell types from each other. In this paper we capitalize on the fact that MNC and RBC display different acoustophysical pr
BACKGROUND: The medical programme at Lund University, Sweden, has undergone curricular reform over several stages, which is still ongoing. Students have been somewhat negative in their evaluations of the education during this time. AIM: To find out how the students perceived the educational climate using the Dundee Ready Education Environment Measure (DREEM), and to compare the findings taken at t
