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INTRODUCTION: Long-term survival following lung transplantation (LTx) faces impediments due to chronic lung allograft dysfunction (CLAD), while infections hinder short-term survival. Fungal colonization and invasive fungal infections (IFI) are common within the first year after LTx. There is ongoing debate regarding the impact of such events on CLAD development and mortality. This study aims to in
INTRODUCTION: Ageing right care(fully) is a transnational research study which explores and maps an understanding of the care pathways between ageing in place and hospital at home policy and practices for older adults in Israel, the Netherlands and Sweden. The countries are suited to be compared where they have growing, ageing populations, a focus on healthcare reform and several policies to reduc
Lung transplantion (LTx) recipients have low long-term survival and a high incidence of bronchiolitis obliterans syndrome (BOS), an inflammation of the small airways in chronic rejection of a lung allograft. There is great clinical need for a minimally invasive biomarker of BOS. Here, 644 different proteins were analyzed to detect biomarkers that distinguish BOS grade 0 from grades 1-3. The plasma
Ex vivo culture of primary acute myeloid leukemia (AML) cells is notoriously difficult due to spontaneous differentiation and cell death, which hinders mechanistic and translational studies. To overcome this bottleneck, we have implemented a co-culture system, where the OP9-M2 stromal cells support the growth, but most notably limit the differentiation of primary AML cells, thus allowing for mecha
Background: Biomarkers serve as a quantitative measure of brain injury and may predict cognitive outcome after cardiac arrest. This study investigates the association and predictive accuracy of acute changes in Alzheimer disease-associated biomarkers to cognitive outcome in cardiac arrest survivors.Methods: Retrospective study of the Target Temperature Management after Out-of-Hospital cardiac arreBackground: Biomarkers serve as a quantitative measure of brain injury and may predict cognitive outcome after cardiac arrest. This study investigates the association and predictive accuracy of acute changes in Alzheimer disease-associated biomarkers to cognitive outcome in cardiac arrest survivors.Methods: Retrospective study of the Target Temperature Management after Out-of-Hospital cardiac arre
Lost Farm Festival transformed an abandoned farm into a global gathering point for grief, anger and creativity – where concerts, rituals and installations turned Sjællands Odde into a new center of the world.
The incidence of melanoma is rising and will require more efficient diagnostic procedures to meet a growing demand. Excisional biopsy and histopathology is still the standard, which often requires multiple surgical incisions with increasing margins due inaccurate visual assessment of where the melanoma borders to healthy tissue. This challenge stems, in part, from the inability to reliably delinea
Transfecting clonal beta cells with large DNA plasmids holds significant promise for diabetes research. Existing transfection techniques like lipofection, viral transduction, and bulk electroporation often face limitations such as low efficiency and cytotoxicity. Nanoelectroporation, which utilizes nanopores or nanostraws and the application of mild electrical pulses, offers a gentle and safe alte
Objectives To investigate the association of diabetes, hypertension and overweight/obesity with physical activity (PA), self-efficacy for pain and self-efficacy for other symptoms before and after a 6- week exercise and education intervention for knee and hip osteoarthritis (OA), and to assess outcome disparities based on metabolic health. Methods Register-based cohort study using the Swedish Oste
Denna studie avsåg att reliabilitetspröva självskattningsinstrumentet VRI-Lund på personer som upplever sig vara röstfriska. VRI-Lund avser att mäta patienters upplevelser av röstbesvär och består av fyra subskalor med tio påståenden i var skala: hals, fysiologisk, emotionell och funktionell samt en egen röstbedömning med Visuell Analog Skala (V AS). Svaren sker genom en skattning på en frekvensba
Ledstjärnan inom svensk miljörätt är att förebygga skador på människor och miljö i så stor utsträckning det är rimligt och möjligt. Utöver dessa preventiva regler finns även reparativa krav som aktualiseras först när en skada på miljön redan skett. Dessa reparativa krav grundar sig i ”principen om att förorenaren ska betala” vilket innebär att den som har orsakat en skada på miljön är ansvarig förThe main purpose of the Swedish Environmental Code is to prevent damage on the environment. In addition to this the Code also contains restorative requirements that apply only when an environmental damage has already occurred. These reparative claims are based on the so called ”Polluter Pays Principle” which states that the one who caused the damage to the environment is liable for the restorative
Syfte: Syftet med denna uppsats är att beskriva arbetet i ett antal revisionsutskott samt att diskutera hur detta arbete har påverkat extern revision och intern kontroll. Metod: En kombination av kvantitativ och kvalitativ metod har använts. Datainsamling har genomförts i form av intervjuer och dokumentstudier. Uppsatsens forskningsansats har varit abduktiv och deskriptiv. Teoretiskt perspektiv: D
Bakgrund: Stroke är en folksjukdom som drabbar många i Sverige och är en vanlig orsak till dödsfall. Sjukdomen orsakas av syrebrist i hjärnan, vilket kan leda till många olika varianter av funktionsnedsättningar bland de individer som överlever. En inaktiv livsstil är en av många riskfaktorer för stroke och fysisk aktivitet har tidigare visat sig vara ett effektivt verktyg för att minska risken fö
