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Repetitive work and work in constrained postures are risk factors for developing musculoskeletal disorders. Low-cost, user-friendly technical methods to quantify these risks are needed. The aims were to validate inclination angles and velocities of one model of the new generation of accelerometers with integrated data loggers against a previously validated one, and to compare meaurements when usin
Allogeneic hematopoietic stem cell transplantation (allo-SCT) is a potentially curative treatment option for eligible patients with chronic lymphocytic leukemia (CLL). However, it is known that cure of CLL is only possible if a graft-versus-leukemia effect is present. Between 1994 and 2007, 48 adults underwent allo-SCT for poor-risk CLL in Sweden. Of these, ten (21%) patients aged 24-53 years (med
Objective: Apart from improved health outcomes, treatment convenience per se may have a value to individuals. This is sometimes referred to as process utility and can be estimated in terms of willingness-to-pay (WTP) or quality-adjusted life-years (QALYs). Previous research has produced multiple studies on QALY gains and WTP estimates of insulin-related attributes. There are, however, significant
Introduction Trastuzumab is part of the standard treatment for HER2-positive breast cancer. The aim of this study was to estimate the societal value of trastuzumab administered through subcutaneous (SC) injection compared to intravenous (IV) infusion. Methods Female patients with HER2-positive breast cancer receiving SC or IV trastuzumab were consecutively enrolled from five Swedish oncology clini
AIMS: To evaluate the efficacy and safety of oral semaglutide for type 2 diabetes mellitus (T2DM) in patients with metabolic dysfunction-associated steatotic liver disease (MASLD).MATERIALS AND METHODS: This was a single-arm, multicentre, prospective study. Among 80 consecutive patients with MASLD and T2DM who newly received oral semaglutide, 70 completed 48-week oral semaglutide treatment as sche
Background: Small bowel neuroendocrine tumours often present with locally advanced or metastatic disease. The aim of this paper is to provide evidence-based recommendations regarding (controversial) topics in the surgical management of advanced small bowel neuroendocrine tumours. Methods: A working group of experts was formed by the European Society of Endocrine Surgeons. The group addressed 11 cl
Background: Digital work can be cognitively challenging especially for people with cognitive difficulties. New occupational therapy interventions are needed to empower these persons to self-manage challenges in digital work and everyday life. To address this need, the internet-based intervention 'Strategies for Empowering Activities in Everyday Life' (SEE 2.0) was tested.Aim: To explore and descri
Human biomonitoring (HBM) frameworks assess human exposure to hazardous chemicals. In this review, we discuss and summarize sample preparation procedures and analytical methodology for six groups of chemicals of emerging concern (CECs), namely diisocyanates, benzotriazoles, benzothiazoles, 4-methylbenzylidene camphor, isothiazolinones, fragrances, and non-phthalate plasticizers, which are increasi
Many studies have underscored the impacts of drought on ecosystems, and some researchers reported the effects of accumulated soil moisture deficit (ASMD) on light use efficiency (LUE) in grassland. However, the potential effects of ASMD on gross primary productivity (GPP) and LUE for both cropland and forest ecosystems are still not understood. This study elucidated the effects of accumulated and
Background: Retention of study participants in observational studies is essential to maintaining the representativeness of the population, minimizing selection bias, and assuring sufficient statistical power. The aim of this report is to describe the structures and strategies used to retain participants in The Environmental Determinants of Diabetes in the Young (TEDDY) Study, an observational stud
This Letter presents the first search for supersymmetry in final states containing one isolated electron or muon, jets, and missing transverse momentum from root s = 7 TeV proton-proton collisions at the LHC. The data were recorded by the ATLAS experiment during 2010 and correspond to a total integrated luminosity of 35 pb(-1). No excess above the standard model background expectation is observed.
The European Union’s (EU) ‘market-oriented’ approach to renewable energy development risks undermining the ability of individual citizens to meaningfully contribute to, and benefit from, a decentralised, localised, and decarbonised energy system. In spite of the EU’s ambition to involve local communities for co-driving a low-carbon energy transition, there is no comprehensive analysis uncovering t
The aim of this study was to research the assessment of a reasonable standard of living in relation to a holistic view regarding the right of care in a nursing home. Our selection of empirical material was 6 judgements from Swedish courts and 16 social inquiry from local authorities of social work. The material was limited to dismissal of the right of care in a nursing home, within the years of 20
The low-carbon benefits and emissions savings from circular economy (CE) strategies are not yet well understood, yet are crucial for global development within Planetary Boundaries. Using the mineral fraction of waste incinerator bottom ash (MIBA) as construction material in road construction is one application of a CE strategy that could lead to environmental gains by substituting energy-intensive
Att stå som tilltalad i en brottmålsprocess är en utsatt situation. Har den tilltalade en psykisk störning kan vi tala om en särskilt utsatt situation. Frågan är vem som bär ansvar för att den tilltalade med psykisk störning får det stöd denne är i behov av, för att effektivt kunna delta i förfarandet och få en rättvis rättegång. Syftet med undersökningen har varit att utreda hur man i dagens brTo be the defendant in a court room is a situation of vulnerable exposition. When suffering from psychiatric disorders, the defendant is likely to be even more vulnerable. The question is who carries the responsibility to deliver adequate support in order to ensure the defendant receives a fair trial. The aim with this paper was to investigate the prosecution of defendants suffering from psychiat
Introduction The Problematic Experience of Therapy Scale (PETS) identifies barriers to home-based exercise programs but has not been validated in hand therapy populations. This study aimed to translate the extended PETS into Swedish and evaluate its content and construct validity in patients undergoing early sensory relearning following peripheral nerve injury.Methods The PETS was translated into
