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Advances in liquid chromatography–mass spectrometry have significantly improved proteomic analyses of human plasma. However, information at the level of intact proteoforms remains limited due to the high dynamic range of protein abundance and the complexity of post-translational modifications. To address this challenge, we introduce soluble plasma proteoform analysis via acetonitrile precipitation

Designing a Comprehensive Institutional Structure to Address Loss and Damage from Climate Change in Bangladesh POLICY BRIEF BY TAHURA FARBIN AND SALEEMUL HUQ, FROM THE PROJECT ’RECASTING THE DISPROPORTIONATE IMPACTS OF CLIMATE CHANGE EXTREMES’ (DICE) | LUND UNIVERSITY AND INTERNATIONAL CENTRE FOR CLIMATE CHANGE AND DEVELOPMENT (ICCCAD) | 2021 Makher Char, Pirojpur, Bangladesh, 2014. Photo by Istia

https://www.lucsus.lu.se/sites/lucsus.lu.se/files/2021-06/Policy%20brief_Designing%20a%20Comprehensive%20Institutional%20Structure%20to%20Address%20Loss%20and%20Damage%20from%20Climate%20Change%20in%20Bangladesh%5B1%5D.pdf - 2026-06-01

OBJECTIVES: Acute Type A aortic dissection remains a life-threatening disease, but there are indications that its surgical mortality is decreasing. The aim of this report was to study how surgical mortality has changed and what influences those changes.METHODS: Nordic Consortium for Acute Type A Aortic Dissection is a retrospective database comprising 1159 patients (mean age 61.6 ± 12.2 years, 68%

Popular Abstract in Swedish Cystisk Fibros Cystisk Fibros (CF) är en relativt vanlig ärftlig sjukdom. Ungefär 1/37 personer i Sverige bär på anlag till CF, men bärare har inga symptom och vet därför inte att de har anlagen. För att få sjukdomen måste fostret få två anlag, ett från vardera föräldern, vilket är 25% risk vid varje graviditet för föräldrapar där båda är bärare. CF är en dödlig sjukdomCystic Fibrosis (CF) is a severe hereditary disorder leading to progressive deterioration of lung function and death. This thesis describes the demography of CF in Sweden, its treatment, with special reference to physiotherapy, and its effects on lung function and peak working capacity (PWC). The study is based on Swedish CF patients and evaluates our current CF treatment package, which differs fr

Objective- The Wnt/β-catenin pathway orchestrates development of the blood-brain barrier, but the downstream mechanisms involved at different developmental windows and in different central nervous system (CNS) tissues have remained elusive. Approach and Results- Here, we create a new mouse model allowing spatiotemporal investigations of Wnt/β-catenin signaling by induced overexpression of Axin1, a

The effects of changing NMDA receptor subunit composition on synaptic plasticity in the hippocampus were analyzed by creating transgenic mice overexpressing NR2D, a predominantly embryonic NMDA receptor subunit. NMDA-evoked currents in the transgenic mice had smaller amplitudes and slower kinetics. The transgenics also displayed age-dependent deficits in synaptic plasticity in area CA1 of the hipp

Background: Prognostication of neurological outcome in patients who remain comatose after cardiac arrest resuscitation is complex. Clinical variables, as well as biomarkers of brain injury, cardiac injury, and systemic inflammation, all yield some prognostic value. We hypothesised that cumulative information obtained during the first three days of intensive care could produce a reliable model for

Loneliness in advanced age has become one of the societal concerns considering its detrimental effects on physical and mental health of older people. Information and communication technologies show the potential to prevent or tackle loneliness and social isolation among older people. Given a percentage of the older population feeling lonely, loneliness in older age has been increasingly recognized

Background: Head computed tomography (CT) is a guideline recommended method to predict functional outcome after cardiac arrest (CA), but standardized criteria for evaluation are lacking. To date, no prospective trial has systematically validated methods for diagnosing hypoxic-ischaemic encephalopathy (HIE) on CT after CA. We present a protocol for validation of pre-specified radiological criteria

Background/Aim: Signs of hypoxic ischaemic encephalopathy (HIE) on head computed tomography (CT) predicts poor neurological outcome after cardiac arrest. We explore whether levels of brain injury markers in blood could predict the likelihood of HIE on CT. Methods: Retrospective analysis of CT performed at 24–168 h post cardiac arrest on clinical indication within the Target Temperature Management

The purpose of this thesis is to try to establish a mechanism that will enable the Commission on the Limits of the Continental Shelf to get access to legal interpretation of the United Nations Convention on the Law of the Sea. The mandate of the Commission is to validate the outer limits line delineated by coastal States. For that, the Commission has to apply provisions of the Convention. The use

A French book relating to flea literature has recently been discovered at the National Library of Sweden in Stockholm. This article claims to be the first presentation of the work Histoire d’une puce by Louis Marie Céleste d’Aumont, Duke of Piennes (1762-1831), with the first literary analysis of its erotic content. The second half of the story is remarkable for the presence of Swedish words in th

Importance: International guidelines recommend body temperature control below 37.8 °C in unconscious patients with out-of-hospital cardiac arrest (OHCA); however, a target temperature of 33 °C might lead to better outcomes when the initial rhythm is nonshockable. Objective: To assess whether hypothermia at 33 °C increases survival and improves function when compared with controlled normothermia in

Paul McMillan Lund Observatory, Box 43 SE-221 00 Lund, Sweden +46 46 22 27312 paul@astro.lu.se EDUCATION University of Leicester, Department of Physics and Astronomy 2003-2006 PhD in Theoretical Astrophysics, awarded 2007 Thesis title: Numerical simulations of galaxy interaction Supervisor: Prof Walter Dehnen Included three-month Marie Curie fellowship at Observatoire de Marseille, Université d

https://www.astro.lu.se/sites/astro.lu.se/files/2022-06/McMillan_CV_and_PublicationList_0.pdf - 2026-06-01

THEIA_Malbet_Lund_2023-v2 Theia : MicroArcsecond Astrometric Observatory From Earth-like Planets to Cosmology: The New Astrometry Frontier Fabien MALBET IPAG / Univ. Grenoble Alpes Astrometry Roadmap Workshop - Lund 2023 Theia - MicroArcsecond Astrometric Observatory Astrometry Roadmap Workshop - Lund 2023 Theia core team 2 Europe Antonio Amorim (Universidade de Lisboa, CENTRA, Portugal) Guillem A

https://www.astro.lu.se/sites/astro.lu.se/files/2023-07/THEIA_Malbet_Lund_2023-v2_0.pdf - 2026-06-01

1 Research School in Medical Science MEFMV1F, 13.5 hp Examiner: Jan Lexell 2 1. Introduction Welcome to the Research School in Medical Science at the Faculty of Medicine, Lund University! We offer a course package to provide the basics in scientific theory, methods, statistics, and ethics, as well as skills for communicating science. Together the aim of the research school is to help you achieve t

https://www.intramed.lu.se/en/sites/intramed.lu.se.en/files/2023-09/Study%20guide,%20Research%20School%20in%20Medical%20Sciences%2013,5%20credits,%20rev.%202023-09-08-REV.pdf - 2026-06-01

1 Research School in Medical Science MEFMV1F, 14.5 hp Examiner: Jan Lexell 2 1. Introduction Welcome to the Research School in Medical Science at the Faculty of Medicine, Lund University! We offer a course package to provide the basics in scientific theory, methods, statistics, and ethics, as well as skills for communicating science. Together the aim of the research school is to help you achieve t

https://www.intramed.lu.se/en/sites/intramed.lu.se.en/files/2023-11/Study%20guide,%20Research%20School%20in%20Medical%20Sciences%2014,5%20credits,%20rev.%202023-11-30.pdf - 2026-06-01

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https://www.ht.lu.se/media/utbildning/dokument/kurser/LATK01/20182/V_lkomstbrev_LATK01.pdf - 2026-04-24