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A people-centred approach for designing large-scale built-up spaces necessitates systematic anticipation of user’s embodied visuo-locomotive experience from the viewpoint of human-environment interaction factors pertaining to aspects such as navigation, wayfinding, usability. In this context, we develop a behaviour-based visuo-locomotive complexity model that functions as a key correlate of cognit

The age-specific incidence of traumatic brain injury in older adults is rising in high-income countries, mainly due to an increase in the incidence of falls. The severity of traumatic brain injury in older adults can be underestimated because of a delay in the development of mass effect and symptoms of intracranial haemorrhage. Management and rehabilitation in older adults must consider comorbidit

Aim: Target temperature management (TTM) at 32-36 °C is recommended in unconscious survivors of cardiac arrest. This study reports awakening in the TTM-trial. Our predefined hypotheses were that time until awakening correlates with long-term neurological outcome and is not affected by level of TTM. Methods: Post-hoc analysis of time until awakening after cardiac arrest, its association with long-t

Introduction: In Sweden, head computed tomography (CT) is commonly used for prediction of neurological outcome after cardiac arrest, as recommended by guidelines. We compare the prognostic ability and interrater variability of routine and novel CT methods for prediction of poor outcome. Methods: Retrospective study including patients from Swedish sites within the Target Temperature Management afte

Background: Communication with patients and families about serious illness impacts quality of life and helps facilitate decision-making.Objective: To elucidate the pattern of communication about serious illness for patients who have died in an inpatient setting.Design: Three hundred patients from the Swedish Registry of Palliative Care 2015-2017 were randomly selected for manual chart review.Setti

The individual wishes and priorities of patients with advanced disease are too often neglected, making a deck of cards with statements reflecting potential wishes and priorities a useful conversation tool. However, in the most ill patients, the card selection and sorting process may be too strenuous. The aims of this study were to explore the wishes and priorities of patients receiving palliative

The use of digital technologies to deliver primary health care has increased over the past decade. While some technologies have been shown to be medically effective and efficient, the effects of digital primary care on the policy goal of equality in the use of such types of care have not been studied using large register data. The aim of this study was to analyse how digital contacts differ from o

Earlier treatment of breast cancer results in better survival. Screening enables this through detection of tumors before they cause symptoms. On the negative side, some tumors if not detected through screening would not cause symptoms, leading to overdiagnosis. Improvements in image quality allow even earlier detection and diagnosis of even smaller tumors at an even earlier stage. This study aims

Recent years have brought new directionality to university’s work with innovation – increasing the focus on addressing societal challenges and contributing to much broader frames for impact. Working with complex challenges, where no one actor can do everything by themselves, requires collaboration across actor groups (private sector, academia, public sector, civil society), industrial sectors, dis

Oath-taking during Roman Antiquity constitutes a telling example of how words and matter interplay and relate to one another. Ancient Latin literature provides a myriad of representations of oaths sworn, both fictive and supposedly historical, where matter somehow figure in the procedure. In this study, a selection of personal oaths from Roman literature are explored in terms of materiality and ag

More than ever, Machine Learning (ML) as a subfield of Artificial Intelligence (AI) is on the rise and is finding its way into safety-critical software applications. However, when it comes to quality assurance (QA) and trustworthiness, integrating ML models into software comes with challenges that may not be apparent at first glance. The European Union (EU) aims to tackle this problem with new reg

The market for ready-to eat vegetables is increasing, but unfortunately so do the numbers of food-borne illness outbreaks related to these products. A previous study has identified bacterial strains suitable for biocontrol of leafy green vegetables to reduce the exposure to pathogens in these products. As a tentative safety evaluation, five selected strains (Rhodococcus cerastii MR5x, Bacillus coa

Purpose/Objective(s): To report the efficacy and utility of PSMA-based molecular targeted imaging in localized prostate cancer using 111In-J591 SPECT and 89Zr-J591 immuno-PET.Materials/Methods: Initiated in 2010, two sequential phase 0 prospective studies were performed on a total of 19 patients evaluating the roles of 111In-J591 SPECT and 89Zr-J591 immuno-PET. All patients had a baseline MRI foll

• The Arctic is continuing to warm faster than any other region on Earth, but key uncertainties remain in our knowledge of the Arctic carbon cycle. • We review the most current knowledge pertaining to estimates of arctic greenhouse gas components and discuss uncertainties associated with these measurements and models. • While the Arctic Ocean is consistently estimated as a carbon sink, we have yet

The existence of impartial and independent courts is a cornerstone of the success of the European project. The recent renaissance of “illiberal States” jeopardises the application of the rule of law and risks destroying the foundations of the EU legal order. In 2018, the Court of Justice of the European Union (CJEU) began developing two new lines of case-law. Firstly, the CJEU found itself to be c

In upholstery applications, it is common to use polyurethane (PUR) foam when flexibility is desired. However, as PUR is a carbon-based material produced using toxic isocyanates, it is environmentally beneficial to replace PUR with bio-based alternatives. The challenge, however, lies in finding suitable bio-based replacement materials, capable of mimicking the foam-like functionality of PUR since m