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Remarks on the Sceptical Turn in the Historiography of the Haitian Revolution : Lessons from the Art of Abstraction

One of the major arguments made in the current boom in Haitian revolutionary studies connects today’s conditions of possibility for modern democracy and human rights to the abolition of slavery during the Haitian Revolution (1791–1804). During the last decade, however, this connection between the Haitian Revolutionary period and our own age has been questioned by an increasing number of scholars:

Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis

People with kidney disease are disproportionately affected by atherosclerosis for unclear reasons. Soluble urokinase plasminogen activator receptor (suPAR) is an immune-derived mediator of kidney disease, levels of which are strongly associated with cardiovascular outcomes. We assessed suPAR’s pathogenic involvement in atherosclerosis using epidemiologic, genetic, and experimental approaches. We f

Metabolite-induced in vivo fabrication of substrate-free organic bioelectronics

Interfacing electronics with neural tissue is crucial for understanding complex biological functions, but conventional bioelectronics consist of rigid electrodes fundamentally incompatible with living systems. The difference between static solid-state electronics and dynamic biological matter makes seamless integration of the two challenging. To address this incompatibility, we developed a method

Adipocyte size and function in the epididymal and inguinal fat depots

Nearly 60% of the worlds adult population is projected to be overweight or obese by 2030. The prevalence of obesity- related diseases, such as type 2 diabetes (T2D), has increased markedly in the past decades. The adipose tissue plays an important role in disease progression of T2D. Adipocyte insulin sensitivity, adipose tissue’s ability to expand, and accumulation of subcutaneous rather than visc

Novel oral anticoagulant use in adults with congenital heart disease : a single-center experience report

Background: Adults with congenital heart disease (ACHD) are a group with an increased risk of thromboembolic complications and arrhythmias. Vitamin K antagonists are the most commonly used thromboprophylaxis therapy in this population. Studies on the efficacy and safety of novel oral anticoagulants (NOAC) are scare in ACHD. A retrospective study on ACHD patients on NOAC treatment registered in the

Off-design performance investigation of a low calorific gas fired two-shaft gas turbine

Gas turbine systems are predominantly designed to be fuelled with gaseous fuels within a limited Wobbe index range (typically HHV=45-55 MJ/Nm3 or 1200-1480 Btu/scf). When low calorific fuel gases are fired, the engine will be forced to operate outside its design envelope. The added mass flow will typically raise the cycle pressure ratio and in two-shaft designs also raise the gas generator shaft s

Sanning och konsekvens för svenska vattenledningar

Detta arbete kick-startar AI (artificiell intelligens) för ledningsunderhåll i VA-branschen i Sverige. Arbetet med befintliga VA-nät är idag främst reaktivt; man reparerar läckor vartefter man blir varse dem, ibland till stora kostnader om läckan är omfattande och akut. Med denna artikel vill vi sätta fokus på proaktivt arbete med ledningsnät och diskutera riskanalys inom området. En ANN-modell soThis work kick-starts AI (artificial intelligence) for pipe management among Swedish water utilities. The current work with pipe management is mainly reactive; leaks are repaired after they are detected, sometimes with large costs if the leakage is extensive and critical. With this article, we want to focus on proactive pipe network management and discuss risk analysis in the field. A previously d

Chemogenetic modulation of cholinergic interneurons reveals their regulating role on the direct and indirect output pathways from the striatum

The intricate balance between dopaminergic and cholinergic neurotransmission in the striatum has been thoroughly difficult to characterize. It was initially described as a seesaw with a competing function of dopamine versus acetylcholine. Recent technical advances however, have brought this view into question suggesting that the two systems work rather in concert with the cholinergic interneurons

Long-term inpatient disease burden in the Adult Life after Childhood Cancer in Scandinavia (ALiCCS) study : A cohort study of 21,297 childhood cancer survivors

Background: Survivors of childhood cancer are at increased risk for a wide range of late effects. However, no large population-based studies have included the whole range of somatic diagnoses including subgroup diagnoses and all main types of childhood cancers. Therefore, we aimed to provide the most detailed overview of the long-term risk of hospitalisation in survivors of childhood cancer. Metho

Developing a Code of Ethics for the Swedish audit profession 1923 to 1994 - Juxtaposing the internal and external role of the Code

The purpose of this paper is to conduct an analysis of how the Code of Ethics has been used by FAR as a strategy in the history of the professionalization project of Swedish auditors from 1923-1994. Acknowledging the differences between professional development in the Anglo-Saxon countries and Continental Europe, the study contributes to nuance the theory of profession and deepen our knowledge of The paper presents an analysis of context within which FAR, the Swedish professional association representing accountants has developed and revised the Code of Ethics from 1923 to 1995. The purpose is to enhance our understanding of the choices made as to what ethical rules were verbalized or codified and the motivations behind the codification. Building on Birkett and Evans’ (2005) model for orga

Survival Options, Processes of Change and Structural Transformation : Livelihood diversification among smallholder households in rural Sub-Saharan Africa

The overall objective of this thesis is to understand the role of diversification at household level, its patterns, determinants and effects on rural smallholder farmers in SSA, as well as its implications for the process of structural transformation in SSA. In the thesis, I use a mixed methodology and combine different types of data on rural smallholders in SSA to answer the objectives a review o

Decreased platelet size is associated with platelet activation and anti-phospholipid syndrome in systemic lupus erythematosus

Objectives: . SLE is an autoimmune disease with increased cardiovascular morbidity and platelet activation. In the general population, increased platelet size predicts platelet reactivity and cardiovascular disease. The aim of this study was to investigate whether platelet size related to platelet activation and cardiovascular disease in SLE.Methods: . Fresh blood samples from SLE patients ( n = 1

Neurotrophic Factor Receptors in the Normal and Injured Visual System : Focus on Retinal Ganglion Cells

The focus of this thesis is the life and death of adult retinal ganglion cells (RGCs). RGCs are neurons that convey visual information from the retina to higher centers in the brain. If the optic nerve is transected (ONT), adult RGCs die by a form of cell death called apoptosis, and a general hypothesis is that neurotrophic factors can support the survival of injured neurons.With the intention to The focus of this thesis is the life and death of adult retinal ganglion cells (RGCs). RGCs are neurons that convey visual information from the retina to higher centers in the brain. If the optic nerve is transected (ONT), adult RGCs die by a form of cell death called apoptosis, and a general hypothesis is that neurotrophic factors can support the survival of injured neurons. With the intention to

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

BACKGROUND. Understanding the genetic architecture of cardiac structure and function may help to prevent and treat heart disease. This investigation sought to identify common genetic variations associated with inter-individual variability in cardiac structure and function. METHODS. A GWAS meta-analysis of echocardiographic traits was performed, including 46,533 individuals from 30 studies (EchoGen

Violence : Situation, Speciality, Politics, and Storytelling

This book considers how the concept of violence has been interpreted, used, defined, and explored by social researchers and thinkers. It does not provide a final answer to the question of what violence is or how it should be explained (or prevented), and instead offers a variety of useful ways of thinking about and theorising the phenomenon, mainly from a sociological standpoint. It outlines four This book considers how the concept of violence has been interpreted, used, defined, and explored by social researchers and thinkers. It does not provide a final answer to the question of what violence is or how it should be explained (or prevented), and instead offers a variety of useful ways of thinking about and theorising the phenomenon, mainly from a sociological standpoint. It outlines four