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The paper presents a new global modeling tool, Stratospheric Chemical Transport Model 2. It has been developed for effective three-dimensional multiyear stratospheric chemistry studies, featuring an extensive chemistry scheme, heterogeneous processing on sulfate aerosols, and some polar stratospheric cloud processes. The transport algorithm maintains sub-grid-scale distributions and connects verti
This paper analyses structural economic forces contributing to the current undersupply of affordable housing in Sweden’s third-largest city, Malmö. It operationalizes Anwar Shaikh’s theory of relative prices to analyzethe political economy of housing shortage. The paper argues that existing policy recommendations at the municipal level are primarily informed by a microeconomic approach to price fo
This paper analyses structural economic forces contributing to the current undersupply of affordable housing in Sweden’s third-largest city, Malmö. It operationalizes Anwar Shaikh’s theory of relative prices to analyze the political economy of housing shortage. The paper argues that existing policy recommendations at the municipal level are primarily informed by a microeconomic approach to price f
With population aging, more adults across Europe face competing demands of working for pay and caring for elderly family members. Associated tradeoffs are expected to be negative, gendered, and vary across contexts with different levels of gender equality, public support for eldercare, and work-family balance. Using SHARE data from 2004–20, this study investigates how unpaid caregiving to independ
Developing high-performance, low-cost oxygen evolution reaction (OER) catalysts is crucial for advancing anion exchange membrane water electrolysis (AEMWE) in large-scale industrial green hydrogen production. Herein, We report a glucose-mediated spray pyrolysis method for synthesizing amorphous NiFe bimetal oxide hollow microspheres (A-NiFeOx) with controlled crystallinity, hierarchical porosity,
Hazardous situations involving radioactive, chemical, and other dangerous materials pose significant risks to emergency responders. In such situations, robots can support civil forces in reconnaissance and mitigation. However, this requires the development of robotic systems with novel AI-based assistance functions, operation procedures, and raises new ethical and legal questions. To address these
This paper presents a search for a new Z′ resonance decaying into a pair of dark quarks which hadronise into dark hadrons before promptly decaying back as Standard Model particles. This analysis is based on proton-proton collision data recorded at s = 13 TeV with the ATLAS detector at the Large Hadron Collider between 2015 and 2018, corresponding to an integrated luminosity of 139 fb−1. After sele
Background: Ageing-in-place policies have increasingly shifted elder care responsibilities onto family members. Among older cohabiting couples, one’s partner’s illness significantly impacts the other’s daily life and well-being.Aim: To explore the responsibilities and strategies of caregiving partners in older cohabiting couples from the perspectives of cohabiting caregivers.Methods: A qualitative
We present the design of the vacuum chamber for the LNLS 2T Hybrid Wiggler. The chamber is a 3m long, 1.2mm thick 316L SS tube, which was mechanically pressed into an elliptical shape from an originally round tube. In order to provide the necessary mechanical tolerances, the rather flexible tube is welded to lateral supports that run the complete length of the chamber. Special care has been given
In the 20th century, the scientific community recognized global climate change as a preeminent challenge facing our planet. The primary driver of this predicament was identified as the substantial reliance on fossil fuels, constituting approximately 80% of the world's energy consumption. The combustion of these fossil fuels, particularly those rich in carbon, led to the emission of greenhouse gase
BACKGROUND: The NextFood Project ( www.nextfood-project.eu) started work in 2018 to identify 'Categories of Skills' that students should be equipped with to address the upcoming global challenges within agrifood and forestry disciplines, and involved concepts such as sustainability, technological adaptation and networking. This study is based on the initial skills and competencies mapping, but tak
Introduction: Rimegepant is an oral small-molecule calcitonin gene-related peptide receptor antagonist approved in several countries for acute treatment of migraine and preventive treatment of episodic migraine in adults. This review summarizes the evidence, published to date, for the use of rimegepant as an acute or preventive treatment of migraine. Areas covered: A brief overview of migraine, th
Different rights regarding poor relief – a comparison between the level of reasonable living standards for financial support for the elderly and financial assistanceIn 2003, financial support for the elderly (ÄFS) was introduced in Sweden, which shifted the responsibility for older people in need of financial support from the municipalities to the state. Prior to the reform, the target group recei
Introduction: Evidence-based clinical practice guidelines drive optimal patient care and facilitate access to high-quality treatment. Creating guidelines for rare diseases such as haemophilia, where evidence does not often come from randomized controlled trials but from non-randomized and well-designed observational studies and real-world data, is challenging. The methodology used for assessing av
Introduction: The 2024 ISTH clinical practice guideline (CPG) for treatment of congenital haemophilia, the NBDF-McMaster Guideline on Care Models for Haemophilia Management, and ASH ISTH NBDF WFH guidelines on the diagnosis and management of VWD all utilised GRADE methodology. Aim: Discuss missed opportunities and the methodological approach of the ISTH Guideline in contrast to how GRADE was previ
High-order interactions associated with non-small cell lung cancer (NSCLC) survival may elucidate underlying molecular mechanisms and identify potential therapeutic targets. Our previous work has identified a three-way interaction among pack-year of smoking (the number of packs of cigarettes smoked per day multiplied by the number of years the person has smoked) and two DNA methylation probes (cg0
OBJECTIVES: Small extracellular vesicles (EVs) contain various signaling molecules, thus playing a crucial role in cell-to-cell communication and emerging as a promising source of biomarkers. However, the lack of standardized procedures impedes their translation to clinical practice. Thus, we compared different approaches for high-throughput analysis of small EVs transcriptome.METHODS: Small EVs w
