Filetype
Philadelphia (Ph) chromosome-positive leukemia is characterized by the BCR/ABL1 fusion protein that affects a wide range of signal transduction pathways. The knowledge about its downstream target genes is, however, still quite limited. To identify novel BCR/ABL1-regulated genes we used global gene expression profiling of several Ph-positive and Ph-negative cell lines treated with imatinib. Followi
Background: Symptoms have been identified as a core outcome domain for atopic eczema (AE) trials. Various instruments exist to measure symptoms in AE, but they vary in quality and there is a lack of standardization between clinical trials. Our objective was to systematically evaluate the quality of the evidence on the measurement properties of AE symptom instruments, thereby informing consensus di
Background: Preterm birth is known to constitute the major risk factor for development of germinal matrix-intraventricular hemorrhage (GM-IVH). Head position may affect cerebral hemodynamics and thus may be involved indirectly in development of GM-IVH. Turning the head toward one side may functionally occlude jugular venous drainage on the ipsilateral side while increasing intracranial pressure an
The planetary changes associated with the Anthropocene, including climate change and extinction of species, pose severe threats to civilization, humanity, and the natural world as we know it. They also pose special challenges to the human imagination. To meet these challenges, climate change communicators use narratives. Nonfiction books intended for a general audience employ two radically differe
Background Sirolimus-coated balloons (SCB) are a potential alternative to paclitaxel-coated balloons (PCB) in the context of percutaneous coronary intervention (PCI). However, comparative data between SCB and PCB remain limited. We aimed to compare the outcome of PCI with contemporary PCB or SCB in a real-world clinical setting. Methods The Swedish Coronary Angiography and Angioplasty Registry (SC
Genetic Contribution to the Divergence in Type 1 Diabetes Risk Between Children From the General Population and Children From Affected Families Genetic Contribution to the Divergence in Type 1 Diabetes Risk Between Children From the General Population and Children From Affected Families Markus Hippich,1 Andreas Beyerlein,1,2 William A. Hagopian,3 Jeffrey P. Krischer,4 Kendra Vehik,4 Jan Knoop,1 Ch
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-12/103%2005072019_679_103_MP162_Hippich_Diabetes_2019.pdf - 2026-07-09
Turbulent breakup in emulsification devices is a dynamic process. Small viscous drops undergo a sequence of oscillations before entering the monotonic deformation phase leading to breakup. The turbulence-interface interactions prior to reaching critical deformation are therefore essential for understanding and modeling breakup. This contribution uses numerical experiments to characterize the criti
Context: Medications may become inappropriate for patients in the last phase of life and may even compromise their quality of life. Objective: To find consensus on recommendations regarding deprescribing of medications for adult patients with a life expectancy of six months or less. Methods: Experts working in palliative care or other relevant disciplines were asked to participate in this internat
This study uses a novel approach to identifying local contextual conditions conducive, alone or in combination to far-right political violence. The studied case is asylum housing attacks occurring in Sweden 2015-16. Using a fuzzy-set qualitative comparative analysis of eighty-six Swedish municipalities, forty-two of which have experienced arson attacks against refugee housing facilities, we operat
Background: Some groups of migrants have increased vulnerability to Sexually Transmitted Infections (STI) and Human Immunodeficiency Virus (HIV) transmission partly due to a lower uptake of disease preventive activities targeting the general population in receiving country. Limited access to economic and social resources and poor language skills may exacerbate exposure to sexual risks and utilizat
Popular Abstract in Swedish Ta ett djupt andetag och tänk på vad du nu har i lungorna! Jo, det är luft, förstås, syre kväve och sådant. Men det är också något annat. I varje kubikcentimeter du andas in finns tusentals partiklar, alla för små för att kunna ses med blotta ögat. Om dessa partiklar handlar denna avhandling. Vi kallar luftburna partiklar för aerosoler, ett begrepp som innefattar allt Airborne particles are everywhere around us, and have always been. Particles generated by human activities has increased drastically since industrialization, and several epidemiological studies have shown that inhaled particles can cause adverse health effects. The concern about health effects have during the last decade shifted towards fine and ultrafine particles, not least due to the emerging f
Introduction: Planning cranioplasty (CPL) in patients with suspected or proven post-traumatic hydrocephalus (PTH) poses a significant management challenge due to a lack of clear guidance. Research question: This project aims to create a European document to improve adherence and adapt to local protocols based on available resources and national health systems. Methods: After a thorough non-systema
In light of the escalating global polycrisis—a convergence of environmental, social, and mental health crises—this paper explores the potential of mindfulness-based approaches for fostering human and planetary wellbeing and sustainability. We specifically investigate the linkages between Mindfulness-Based Stress Reduction (MBSR) and sustainability, and how they can be strengthened to support trans
INTRODUCTION: There is substantial heterogeneity in the reporting of outcomes in the global cranioplasty literature. This study aimed to establish a core outcome set (COS) for cranioplasty after decompressive craniectomy for stroke or traumatic brain injury.METHODOLOGY: The scope was defined according to the criteria recommended by the Core Outcome Measures in Effectiveness Trials (COMET) Initiati
Syftet med vår undersökning är att ge förslag på vad ansvariga på mansdominerade företag bör tänka på vid utformningen av sin interna- och externa kommunikation samt hur dessa kan samverka då mansdominerade företag önskar attrahera fler kvinnliga medarbetare. Vi har valt att använda oss av relevanta teorier som kopplar samman marknadskommunikation (intern- och extern kommunikation), rekrytering (a
MOS Variabellista inkl frekvenser - Halvtidskontroll (2018-06-13) Sida 1 av 50 Nr Name Format Variable label File Checked #B #BB Deltagare 1 lopnrMOS Numeric Löpnummer vid MOS baslinjeundersökning (Numerisk) MOS_Deltagare_halvtid.savAD 1326 1321 2 lopnrMOS_str8 String Löpnummer vid MOS baslinjeundersökning (Sträng, utan mellanstreck)MOS_Deltagare_halvtid.savAD 1326 1321 3 lopnrMOS_str9 String Löpn
