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Background: Relapse of hepatitis C virus (HCV) infection after liver transplantation (LT) is universal. Tolerance for treatment with pegylated-interferon (peg-IFN) and ribavirin (RBV) is suboptimal and withdrawals due to adverse events frequent. We sought to improve tolerance for treatment to improve outcome. Methods: We used concentration-guided RBV dosing to achieve an intended 10 mu mol/L conce

Strut-based structures, such as lattices, produced using additive manufacturing (AM) offer significant potential for applications requiring lightweighting and structural compliance. However, conventional Design for AM (DfAM) approaches often assume idealised material behaviour, which can be misleading for thin strut-based structures where geometric parameters and process-induced effects significan

The rapid progression of the electrification of road transport in many countries urges the need to make informed decisions on the location and size of the required charging infrastructure. This paper’s main contribution is a novel method to position fast-charging stations based on the transportation energy demand and to evaluate the performance of such charging infrastructure. Depending on their r

Over the past decade, there has been increasing interest in the use of grounded theory in information systems research. Grounded theory is a qualitative research method that seeks to develop theory that is grounded in data systematically gathered and analysed. The purpose of this paper is to suggest guidelines for grounded theory studies in information systems. Our guidelines are based on a framew

In recent years, researchers worldwide have become increasingly interested in the phenomenon of code-switching in the multilingual classroom. The paper aims to try to understand when and why teachers in Swedish for Immigrants (SFI) schools code-switch in their classrooms. It analyses the methods and reasons for teachers’ code-switching in the SFI classroom. A case study was conducted by means of a

This thesis examines the extent to which the judgment of the Court of Justice of the European Union in Commission v Belgium (C-524/23), regarding Belgium’s failure to comply with the Directive by failing to correctly transpose Article 8(7) of the Anti-Tax Avoidance Directive (ATAD) into its domestic legal framework, impacts the Dutch transfer pricing rules under Article 8b of the Corporate Income

Objectives To assess the performance of the ALL IN TRIPLEX rapid antigen-based test for SARS-CoV-2, influenza A, influenza B, and respiratory syncytial virus. We focus on the potential of the test to be used in acute clinical settings as a marker of infectiousness, by determining the sensitivity at different real-time PCR cycle threshold (Ct) levels, as well as the quantity of absorbed viral RNA n

Families living with a person with mental illness can experience distress requiring therapeutic interventions. Web-based mindfulness interventions have shown beneficial health outcomes for both clinical and healthy populations, and may help families cope and overcome barriers that can otherwise hinder a help-seeking process. Aims: To develop and assess outcomes of a web-based mindfulness intervent

Ultrasound optical tomography enables noninvasive characterization of tissue and lesions up to 5 cm below the skin surface, by enhancing diffuse optical tomography with ultrasound focusing resolution and an increased number of measurement points. For optimal clinical imaging, it is essential to be able to reconstruct tissue optical properties in real time during in vivo measurements, and therefore

This article explores the complex relationship between performance programs in higher music education and the evolving demands of current and future professional music scenes. Drawing upon career anchor theory and enactive cognitive science, it introduces a workshop-based framework to support students in reflecting on future working life. The framework decenters ideas of entrepreneurship and marke

In the post-World War II era, international lawyers have occupied the front seat in the study of international organisations (IOs). During the past decade, this disciplinary hierarchy has grown to feel increasingly unsatisfying. This chapter offers an anthropological take on the study of IOs building both on the past decade of anthropological work and my ethnography at the UN Human Rights Committe

With two centuries of forestry, natural forests in boreal Sweden are rare and strongly fragmented. Hence, restoration aiming to improve conditions for forest biodiversity is needed. However, to ensure landscape connectivity – where to restore is a critical concern.Our study objective was to identify connectivity forest that through restoration support connectivity and biodiversity. The study area

Repair entails the fixing of one or several specific malfunctions or performance issues in order to return a product to proper condition or functioning. Issues requiring repair can be cosmetic (e.g., a scratch or dent), functional (e.g., the product does not turn on), or both (e.g., the product’s screen is broken). For every product that is successfully repaired instead of replaced, the need to ma

The case company under study has conducted a continuous process of business model innovation for sustainability since 2007, but is suffering from barriers present in the process. The limited amount of literature on business model innovation for sustainability provides little guidance on barriers. Therefore, this research aims to contribute to the literature by identifying what barriers are present

Denna studie syftar till att undersöka hur lärande för hållbar utveckling (LHU) kan implementeras på arbetsplatsen. Detta med bakgrund i att vi idag genomgår en klimatkris och att det krävs en total omställning av samhällets alla sektorer för att hålla den globala temperaturökningen under 1.5 grader. Uppsatsen syftar till att synliggöra vikten av att LHU blir ett systematisk inslag på arbetsplatse

By the end of the 1960s there was a growing environmental concern all around the globe. As a part of an answer to this challenge the need was recognized for a reorientation of the education processes towards developing knowledge, attitudes and skills for resolving the issues. This was the birth of the concept of Environmental Education (EE). However, this notion is far from being static as it went

In the European Union there are special schemes in Value Added Tax that Member States may adopt. Those rules are set out in the VAT Directive. Two of those special schemes are the special scheme for small enterprises and the common flat-rate scheme for farmers. Along to the provisions of the VAT Directive there is also some case law from the CJEU that clarifies the application of the schemes. Ger