Search results

The interactions between aerosols and clouds are still one of the largest sources of uncertainty in quantifying anthropogenic radiative forcing. To reduce this uncertainty, we must first determine the baseline natural aerosol loading for different environments. In the pristine and hardly accessible polar regions, the exact nature of local aerosol sources remains poorly understood. It is unclear ho

Introduction: Doxorubicin (DOX), a potent anthracycline, is widely used in cancer therapy, but its effect is limited by doxorubicin-induced cardiotoxicity (DIC). Increasing evidence suggests that DIC is associated with ferroptosis, a cell death characterized by the iron-dependent accumulation of lipid peroxides. Although aerobic exercise is recommended for chemotherapy-related cardiac dysfunction,

A spectrally and polarization-resolved wavefront detector can measure the spatio-temporal vector electric field of ultrashort laser pulses in a single shot.

The expansion of the electric vehicle industry is driving increased demand for lithium-ion batteries (LIBs), which in turn creates challenges in material availability and waste management that more durable LIBs could address. Electrode surface coating helps extend LIB lifespan, with atomic layered deposition (ALD) as the preferred method due to its precise thickness control and ability to coat var

The dispersion-scan technique (d-scan) is a well-established technique for the measurement of ultrashort laser pulses. While a single-shot version of d-scan is relatively easy to implement for sub-10 fs laser pulses, this becomes increasingly difficult as the pulse duration increases due to the need for a larger dispersion range, which scales quadratically with the Fourier transform limit (FTL). H

Insulin resistance (IR) contributes to atherogenic dyslipidemia and elevated ASCVD risk. Apolipoprotein A1 (ApoA1)-associated lipoproteins have diverse anti-atherogenic functions, but it is unclear whether IR drives adverse changes in their proteomic composition. We hypothesized that IR is associated with an atherogenic ApoA1 proteome and that insulin-sensitizing interventions would improve its co

Photonic topological insulators and self-induced nonreciprocity based on nonlinear effects in asymmetric structures have garnered increased attention due to their potential applications in quantum information technologies and advanced photonic integrated circuits. In this study, we combine these two fields and present asymmetric photonic crystal designs based on all-dielectric checkerboard structu

Objective Delivery of a small for gestational age (SGA) infant is a common pregnancy complication among women with SLE. Although disease activity and autoantibodies such as anti-Smith and anti-ribonucleoprotein associate with SGA, underlying pathological mechanisms remain unclear and reliable predictors are lacking. To address this, we applied a proteomic approach to identify proteins associated w

Background Preserved ratio impaired spirometry (PRISm) and restrictive spirometry pattern (RSP) are associated with increased morbidity and mortality, but the underlying mechanisms are unclear. Impulse oscillometry (IOS) measures small airway function more sensitively than spirometry. We aim to study the prevalence of abnormal IOS findings in relation to three spirometry patterns (obstructive, PRI

BACKGROUND: Cardiovascular calcification is a significant predictor and contributor to cardiovascular diseases. Vascular smooth muscle cell (SMC)-derived extracellular vesicles (EVs) play a crucial role in microcalcification formation. EVs can originate from the endosomal system, and PIKFYVE (1-phosphatidylinositol 3-phosphate 5-kinase), a lipid kinase, plays a key role in endomembrane maturation.

IntroductionSport-related concussion (SRC) is a pressing issue in Para sport, yet biomechanical mechanisms remain poorly understood. Athletes with visual impairment face elevated risks due to sport-specific demands, such as frequent collisions in blind football. This pilot study examined head acceleration responses in blind football players compared with non-disabled football players, and between

Introduction: It is well known that urinary tract infection (UTI) during pregnancy is associated with preterm birth, but information about the risk of preterm birth depending on gestational week of infection is sparingly described in the literature. Material and Methods: An observational study based on data from Swedish registers including women giving birth 2014–2020 (n = 684 595). Pregnant women

Objective: To describe longitudinal changes of Magnetic Resonance Imaging (MRI) features in the medial vs lateral tibiofemoral (TF) and patellofemoral (PF) compartments, in knees with no radiographic osteoarthritis (OA) at baseline. Design: In 340 individuals from the Osteoarthritis Initiative aged 45–55 years (51% women) with 430 knees at risk for OA and 250 not at risk, we assessed MRI scans of

Background: Pro-neurotensin (pro-NT) is the stable circulating precursor of neurotensin (NT), a neuropeptide expressed mainly in the central nervous system and small intestine that regulates key physiological processes like fatty acid absorption in the gut and suppresses appetite via central mechanisms. Studies in NT-deficient mice and humans implicate NT in obesity and insulin resistance, highlig

Hyperbolic phonon polaritons - hybridized modes arising from the ultrastrong coupling of infrared light to strongly anisotropic lattice vibrations in uniaxial or biaxial polar crystals - enable to confine light to the nanoscale with low losses and high directionality. In even lower symmetry materials, such as monoclinic (Formula presented.) -Ga2O3 (bGO), hyperbolic shear polaritons (HShPs) further

Aims: Testing insulin resistance could help improve physician assessment of patients’ risk of prediabetes or type 2 diabetes (T2D), even among normoglycemic individuals. Methods: The longitudinal study followed 16,333 normoglycemic participants in a nation-wide employer-sponsored health assessment program starting in August 2020 with a median follow-up time of 2.9 years for incident prediabetes or

Several factors contribute to the use, non-use, or inadequate use of personal protective equipment (PPE) in construction work. This study aimed to analyse correct usage of various PPE, such as helmet, ear protectors, goggles, respiratory mask, gloves, protective clothing, and a safety harness. Correct usage was assessed as guessability, which refers to human perceptions of how to don, adjust, use,

ObjectivesTo compare head acceleration between blind football players and non-disabled football players, and between anticipated and unanticipated conditions in blind football players.DesignLaboratory-based exploratory study.MethodsParticipants were ten football players (five blind football, five non-disabled; 80% female). Standardized head perturbations were applied in flexion, extension, lateral

Personal Protective Equipment (PPE) noncompliance has been addressed through various lenses. In current literature, there is a greater focus on improving training and safety culture. Improving PPE design to persuade PPE compliance is less explored, especially in sectors beyond healthcare. This study investigates the reasons behind PPE noncompliance across construction, maritime, and chimney sweepi