Filetype
The retail sector is facing fundamental transformations in nearly every part of the value chain, affecting the need for competence development in many retail professions. As most learning at work is informal and there is a deficit of studies of how such learning takes place in specific professions, systematized work with competence development is hampered. We therefore investigated the informal le
Background: Magnetization transfer (MT) saturation reflects the additional saturation of the MRI signal imposed by an MT pulse and is largely driven by the saturation of the bound pool. This reduction of the bound polarization by the MT pulse is less efficient than predicted by the differential B1-square law of absorption. Thus, B1 inhomogeneities lead to a residual bias in the MT saturation maps
Brain tissue segmentation plays a crucial role in feature extraction, volumetric quantification, and morphometric analysis of brain scans. For the assessment of brain structure and integrity, CT is a non-invasive, cheaper, faster, and more widely available modality than MRI. However, the clinical application of CT is mostly limited to the visual assessment of brain integrity and exclusion of copat
Background: The air traffic management (ATM) system has historicallycoped with a global increase in traffic demand ultimately leading toincreased operational complexity.When dealing with the impact of this increasing complexity on systemsafety it is crucial to automatically analyse the losses of separation(LoSs) using tools able to extract meaningful and actionableinformation from safety reports.C
With the help of modern technologies and advances in communication systems, the functionality of Industrial control systems (ICS) has been enhanced leading toward to have more efficient and smarter ICS. However, this makes these systems more and more connected and part of a networked system. This can provide an entry point for attackers to infiltrate the system and cause damage with potentially ca
Hormone-sensitive lipase (HSL) is mainly present in adipose tissue where it hydrolyses diacylglycerol. Although expression of HSL has also been reported in the brain, its presence in different cellular compartments is uncertain, and its role in regulating brain lipid metabolism remains hitherto unexplored. We hypothesized HSL might play a role in regulating the availability of bioactive lipids nec
OBJECTIVES: The objectives of this exploratory study were to investigate the feasibility of multidimensional diffusion magnetic resonance imaging (MddMRI) in assessing diffusion heterogeneity at both a macroscopic and microscopic level in prostate cancer (PCa).MATERIALS AND METHODS: Informed consent was obtained from 46 subjects who underwent 3.0-T prostate multiparametric MRI, complemented with a
BACKGROUND: Patients presenting with peritoneal metastases (PM) of colorectal cancer (CRC) can be curatively treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Angiogenesis is under control of multiple molecules of which HIF1a, SDF1, CXCR4, and VEGF are key players. We investigated these angiogenesis-related markers and their prognostic value in patient
AIM: Twelve to 13% of patients with colorectal cancer (CRC) develop peritoneal carcinomatosis (PC), the majority of whom present with unresectable disease. This study aimed to document the actual response rate to and response characteristics of preoperative modern systemic chemotherapy in this patient group.METHOD: Patients underwent a positron emission tomography (PET)/CT scan, laparoscopy and pe
Doktorsavhandling i Gamla testamentets exegetik. I avhandlingen kartläggs vilka tolkningsstrategier som är tongivande i modern kommentarlitteratur av Psaltarens s.k. 'förbannelsepsalmer,' dvs. bibeltexter som vanligen utelämnas i modernt gudstjänstliv av innehållsliga skäl då de uttrycker den bedjandes önskan om hämnd och/eller våld gentemot fiender. En översikt av den exegetiska diskursen, så somDue to their calls for vengeance and violence the so called imprecatory psalms are generally considered ethically difficult and subsequently omitted from liturgy. This becomes particularly evident in breviaries, such as the Roman Catholic Church’s Liturgy of the Hours, where both entire psalms and individual verses have been omitted. The widespread omission of lament psalms (including imprecatory
International collaboration is clearly a key priority in higher education andresearch (HER) policy and practice. The competition for students and excellentresearch and teaching staff is now a global one and this is reflected inthe increasing salience of phenomena such as the Shanghai and Times HigherEducation Rankings for monitoring the performance of HER institutions. Thischapter takes its point
CHANGES resulting in altered antigenic properties of viruses nearly always occur on their surface and have been attributed to the substitution of residues directly involved in binding antibody. To investigate the mechanism of antigenic variation in foot-and-mouth disease virus (FMDV), variants that escape neutralization by a monoclonal antibody have been compared crystallographically and serologic
Background: The outcome in patients after surgery for acute type A aortic dissection without replacement of the part of the aorta containing the primary tear is undefined. Methods: Data of 1122 patients who underwent surgery for acute type A aortic dissection in 8 Nordic centers from January 2005 to December 2014 were retrospectively analyzed. The patients with primary tear location unfound, unkno
Background: There is insufficient knowledge available about the impact of paediatric palliative care at home on meeting family needs and ensuring the highest quality of care for the dying child. The aim of this study was to elucidate parents’ experiences of how and why home-based paediatric palliative care impacted the entire family during their child's final phase of life. Methods: The study used
AIMS: To report the results of standard therapy for peritoneal carcinomatosis of colorectal origin, which consists of conventional surgery and systemic chemotherapy.METHOD: In a prospective study 50 patients with proven peritoneal carcinomatosis of colorectal origin were treated with conventional surgery combined with 5-fluorouracil and leucovorin, or irinotecan in patients treated by 5-fluorourac
As radiotherapy using ultra-high dose rates has gained new interest, the dosimetric challenges arising at these conditions needs to be addressed. Ionization chambers suffer from a large decrease in ion collection efficiency due to ion recombination, making on-line dosimetry difficult. In this work we present experimental setups and dosimetric procedures for FLASH irradiation of cells, zebrafish em
Feedforward control can be considered as the most well-known control approach to deal with measurable disturbances. It started to be used almost 100 years ago, and since then it is being used in most industrial processes. It is a very simple technique that has been used typically as a complement to PID control, although it can be combined with any feedback controller. The feedforward control desig
