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Systolic inter-arm blood pressure difference and subclinical atherosclerosis : a population-based cohort study of 29921 individuals

Inter-arm blood pressure differences (IABPDs) can be caused by atherosclerosis. We investigated 29921 men and women aged 50–64years from the nationwide population-based Swedish CArdio Pulmonary bioImage Study (SCAPIS) to evaluate if IABPD is related to risk factors for atherosclerosis and can be used as a marker of atherosclerosis as evaluated by coronary artery calcium score, arterial segment inv

Therapies leading to coronary atherosclerosis plaque regression : a scientific statement of the European Association of Preventive Cardiology, the European Association of Cardiovascular Imaging of the ESC, the ESC Working Group on Atherosclerosis and Vascular Biology, and the ESC Working Group on Cardiovascular Pharmacotherapy Part 1: Atherosclerosis Pathophysiology and Imaging Evaluation

Coronary artery disease is one of the leading causes of mortality worldwide. While early identification and treatment of major cardiovascular risk factors are crucial, recent data suggest the possibility of non-invasively detecting early stages of coronary atherosclerosis and potentially stabilizing or even reversing the burden of atherosclerosis with innovative and existing treatments. Moreover,

Innate-like T Cell Biology in the Tumor Microenvironment Implications for Cancer Immunotherapy

Innate-like T cells (ILTCs) link innate immune responses with adaptive immune functions. This group includes invariant natural killer T (iNKT) cells, mucosa-associated invariant T (MAIT) cells, and γδ T cells. ILTCs detect transformed or stressed cells via non-classical antigen presentation pathways. For example, iNKT cells recognize CD1d-presented glycolipids, MAIT cells respond to MR1-presented

What we thought we knew about TNF-And what we now must re-learn

Tumor necrosis factor (TNF) was long cast as a hematopoiesis villain, driving bone marrow and hematopoietic stem cell (HSC) suppression. We now see that TNF's effects are cell type-, context-, and time-dependent. Rather than being simply "bad," TNF can prune progenitors while transiently reprogramming HSCs without sacrificing long-term regenerative capacity.

Prediction of Risk for Myeloid Malignancy in Clonal Hematopoiesis

BACKGROUND Clonal hematopoiesis of indeterminate potential (CHIP) and clonal cytopenia of undetermined significance (CCUS) are defined by somatic mutations in genes associated with myeloid neoplasms (MN) at a variant allele fraction (VAF) of 0.02 or greater in the absence and presence of cytopenia, respectively. CHIP/CCUS is highly prevalent in adults, and defining predictors of MN risk would aid

Threshold-Based Overlap of Breast Cancer High-Risk Classification Using Family History, Polygenic Risk Scores, and Traditional Risk Models in 180,398 Women

Background: Breast cancer polygenic risk scores (PRS) and traditional risk models (e.g., the Gail model [Gail]) are known to contribute largely independent information, but it is unclear how the overlap varies by ancestry, age, disease type (invasive breast cancer, DCIS), and risk threshold. Methods: In a retrospective case–control study, we evaluated risk prediction performance in 180,398 women (

Patched controls cell cycle and tissue architecture in C. elegans gonad.

Hedgehog (Hh) signaling is essential for embryonic development and tissue homeostasis in organisms. However, Caenorhabditis elegans lacks canonical Hh signaling due to the absence of key components, such as smoothened (SMO) and obvious Hh ligands. Despite this, C. elegans retains Patched homologs, ptc-1 and ptc-3, which have specialized independent functions. Although ptc-1 is predominantly ex

Association between habitual dietary taurine intake and the risk of metabolic dysfunction-associated steatotic liver disease : a prospective cohort study

Taurine, an amino sulfonic acid abundant in seafood and meat, has been proposed to have a potential role in the prevention of metabolic dysfunction-associated steatotic liver disease (MASLD) due to its antioxidant and anti-inflammatory properties. However, the association between dietary taurine intake and MASLD remains unclear in human populations. Also, data on dietary taurine intake among adult

Incidence and prevalence of autoimmune disease in the Swedish National Patient Register

Background: Standardized definitions of autoimmune disease (AD) are lacking. Therefore, we aim to propose a definition of AD for register-based research and estimate the burden of AD in Sweden as registered in the National Patient Register (NPR) from 1980 to 2023. Methods: Leveraging the NPR, we defined AD as having at least two relevant International Classification of Diseases (ICD) codes represe

Medical Aspects of Abdominal Aortic Aneurysm

An abdominal aortic aneurysm (AAA) is defined as aortic diameter ≥30 mm measured by ultrasound. AAA prevalence increases with age and is higher in men, but has decreased during the last decades, related to lower smoking rates. Tobacco smoking, concomitant atherosclerosis, arterial hypertension, and family history are the most common risk factors. AAA has atherosclerotic, inflammatory, apoptotic, a

Circle of light the impact of the led lifecycle mespom 2016

Circle of Light The impact of the LED Lifecycle Savannah Carr-Wilson, Elizabeth Drachenberg, Gabrielle Freeman, Ritika Jain, Robyn Kotze, Malgorzata Lekan, Sunanda Mehta, Dann Moreno, Darja Mihailova, Brayton Noll, Sandeep, Sai Siddhartha Nandamuri, Marula Tsagkari, Rongyu Veneta Tzeng Partly funded by: Research by: Cover page designed by Malgorzata Lekan This publication should be cited as: Inter

https://www.iiiee.lu.se/sites/iiiee.lu.se/files/circle_of_light_the_impact_of_the_led_lifecycle_mespom_2016.pdf - 2026-05-08

Tapong sylvester

LUMES 2001/2002 LLUUMMEESS 22000011//22000022 IInntteerrnnaattiioonnaall mmaasstteerr’’ss pprrooggrraamm iinn eennvviirroonnmmeennttaall sscciieennccee--LLUUMMEESS EEnnvviirroonnmmeennttaallllyy bbaasseedd ttrreeaattmmeenntt ooff ssoolliidd wwaassttee iinn uurrbbaann aanndd sseemmii uurrbbaann aarreeaass ooff CCaammeerroooonn BByy TTaappoonngg SSyyllvveesstteerr EEmmaaiill:: ttaappoonnggssyyllvvee

https://www.lumes.lu.se/sites/lumes.lu.se/files/tapong_sylvester.pdf - 2026-05-08

Cfewp20

CFE wp- Nr 20 1EU Treaty Reform in Theoretical Perspective EU Treaty Reform in Theoretical Perspective An Empirical Exploration of Liberal Intergovern- mentalism and Historical Institutionalism Björn Arvidsson bjorn.arvidsson.763@student.lu.se 2 CFE Working paper series no. 20 CENTRE FOR EUROPEAN STUDIES AT LUND UNIVERSITY: Box 52 Phone: +46 (0)46-222 88 99 SE-221 00 LUND Fax: +46 (0)46-222 40 06

https://www.cfe.lu.se/en/sites/cfe.lu.se.en/files/2020-12/cfewp20.pdf - 2026-05-08

Handbok För Hantering Av Brandfarliga Och Explosiva Varor

Handbok för brandskyddsarbete Sida 1 av 78 Lunds universitet, LU Byggnad, Box 117, 221 Lund LU Byggnad Brandskyddssamordnare HANDBOK Diarienummer V 2024/2054 Datum 2024-10-03 Rev. 2026-03-23 Handbok för hantering av brandfarliga och explosiva varor Lunds universitet Version 5 Lunds universitet, LU Byggnad, Box 117, 221 Lund Innehållsförteckning 1. Inledning ........................................

https://www.hr-webben.lu.se/sites/hr-webben.lu.se/files/2026-04/Handbok%20f%C3%B6r%20hantering%20av%20brandfarliga%20och%20explosiva%20varor.pdf - 2026-05-08

Common Susceptibility Loci for Male Breast Cancer

BackgroundThe etiology of male breast cancer (MBC) is poorly understood. In particular, the extent to which the genetic basis of MBC differs from female breast cancer (FBC) is unknown. A previous genome-wide association study of MBC identified 2 predisposition loci for the disease, both of which were also associated with risk of FBC.MethodsWe performed genome-wide single nucleotide polymorphism ge

Clinical Isolates of Acinetobacter spp. Are Highly Serum Resistant Despite Efficient Recognition by the Complement System

Gram-negative bacteria from the genus Acinetobacter are responsible for life-threating hospital-related infections such as pneumonia, septicemia, and meningitis, especially in immunocompromised patients. Worryingly, Acinetobacter have become multi- and extensively drug resistant (MDR/XDR) over the last few decades. The complement system is the first line of defense against microbes, thus it is hig

Effects of Probiotic Bacteria Lactobacillaceae on the Gut Microbiota in Children With Celiac Disease Autoimmunity : A Placebo-Controlled and Randomized Clinical Trial

Disturbances of the gut microbiota may influence the development of various autoimmune diseases. This study investigated the effects of supplementations with the probiotic bacteria, Lactiplantibacillus plantarum HEAL9 and Lacticaseibacillus paracasei 8700:2, on the microbial community in children with celiac disease autoimmunity (CDA). The study included 78 genetically predisposed children for cel