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In Operando Locally-Resolved Photophysics in Perovskite Solar Cells by Correlation Clustering Imaging

The instability of metal halide perovskites limits the commercialization of solar cells despite their impressive efficiencies. This instability, driven by photo-induced ion migration, leads to material restructuring, defect formation, degradation, and defect healing. However, these same “unwanted” properties enable to propose Correlation Clustering Imaging (CLIM), a technique that detects local ph

High-impedance microwave resonators with two-photon nonlinear effects

Nonlinear effects play a central role in photonics as they form the foundation for most of the device functionalities such as amplification and quantum state preparation and detection. Typically the nonlinear effects are weak and emerge only at high photon numbers with strong drive. Here we present an experimental study of a Josephson junction -based high-impedance resonator. We show that by takin

Ovarian cancer linked to lynch syndrome typically presents as early-onset, non-serous epithelial tumors

Objective. Heredity is a major cause of ovarian cancer and during recent years the contribution from germline mismatch repair (MMR) gene mutations linked to Lynch syndrome has gradually been recognized. Methods. We characterized clinical features, tumor morphology and mismatch repair defects in all ovarian cancers identified in Swedish and Danish Lynch syndrome families. Results. In total, 63 epit

Functional integration of new hippocampal neurons following insults to the adult brain is determined by characteristics of pathological environment.

We have previously shown that following severe brain insults, chronic inflammation induced by lipopolysaccharide (LPS) injection, and status epilepticus, new dentate granule cells exhibit changes of excitatory and inhibitory synaptic drive indicating that they may mitigate the abnormal brain function. Major inflammatory changes in the environment encountering the new neurons were a common feature

Frequent mismatch-repair defects link prostate cancer to Lynch syndrome

BACKGROUND: A possible role for prostate cancer in Lynch syndrome has been debated based on observations of mismatch-repair defective tumors and reports of an increased risk of prostate cancer in mutation carriers. Potential inclusion of prostate cancer in the Lynch syndrome tumor spectrum is relevant for family classification, risk estimates and surveillance recommendations in mutation carriers.M

Suppressing Charge Recombination via Cu-Induced Hole Trap in CdS Nanorods for Enhanced Hydrogen Evolution

Solar-driven hydrogen production stores renewable energy chemically but suffers from efficiency limitations due to the slow hole transport-dominated recombination, which caused by high valence band degeneracy and hole effective mass. Targeted hole trap regulation is essential to minimize these losses and enhance photocatalytic H2 evolution performance for practical applications. This study address

Inclusion of eco-corona formation and biotransformation in regulatory nanomaterial ecotoxicity and fate testing : review and insights from the MISTRA environmental nanosafety project

Background: The eco-corona, consisting of environmental biomolecules formed around engineered nanomaterials (ENMs) when released to the environment, has gained increasing focus in the scientific literature and its role for ENM fate and toxicity is now widely acknowledged. The European chemicals legislation, REACH, entails reporting requirements when it comes to the transformation of nanoforms. Gui

Stable-wavelength perovskite nanoplatelet laser via mixed-phase engineering

Perovskites have attracted widespread attention for laser applications due to their excellent optoelectronic properties. However, perovskite lasers typically exhibit a wavelength shift as pump density increases. Here, we report a pump-induced wavelength shift-free laser achieved using a perovskite nanoplatelet with mixed orthorhombic and tetragonal phase. At 293 K, the tetragonal-phase perovskite

Sulfur-ligated iron(iv)-imido and iron(iv)-oxo complexes, which one is more reactive?

Mononuclear iron(iv)-oxo, iron(iv)-imido and iron(iv)-nitrido complexes are common catalytic cycle intermediates in enzymes, where the metal is typically linked to the protein through cysteinate or histidine sidechains. Enzymatic high-valent iron(iv)-imido and -nitrido intermediates have never been trapped and characterized; hence, there is uncertainty regarding their structure and function. Using

Regional differences in birth prevalence of cleft lip and/or palate in Sweden – a register study of all children born in Sweden between 2000 and 2020

The birth prevalence of cleft lip and/or palate (CL/P) varies globally, and regional differences have previously been observed within Sweden. Updated data on CL/P birth prevalence is needed and has been requested nationally and internationally. This study investigated regional differences and temporal trends in the birth prevalences of CL/P and specific cleft subtypes across Sweden’s six health ca

Bright Near-Infrared-Emitting Organic Nanoparticles Based on Small-Molecule Ionic Isolation Lattices

Near infrared (NIR) fluorescence imaging has received significant attention. However, it remains challenging to develop NIR emitters with a high brightness. Herein, we report a supramolecular approach to formulate NIR fluorescent molecular nanoparticles from cationic NIR fluorophores and cyanostar receptors using their charge-by-charge packing in small-molecule ionic isolation lattices (SMILES). F

Novel approaches to the stratified management of knee osteoarthritis

Knee osteoarthritis is a highly prevalent whole-joint disease that is associated with substantial morbidity. If step changes are to be made in the management of knee osteoarthritis, novel patient stratification approaches are needed to identify the most effective treatment for individual patients. Numerous methods for stratifying patients with knee osteoarthritis can be employed; clinical presenta

Atmospheric biogenic ice-nucleating particles link to microbial communities in the arctic marine environment in Western Greenland

Biogenic ice-nucleating particles (INPs) can significantly impact mixed-phase clouds by enhancing precipitation and reducing albedo. As Arctic sea ice diminishes, the exposure of open ocean may increase aerosolization rates of marine bioaerosols and INPs. We investigated INP concentrations and microbial communities in ambient marine air, sea bulk water (SBW), and sea surface microlayer (SML) along

Iron deficiency restrains short-term recovery in patients undergoing surgery for advanced ovarian cancer

BackgroundPatients with advanced ovarian cancer (AOC) who undergo primary and interval debulking surgery are often anemic at diagnosis, with iron deficiency being the most common cause. The aim was to investigate whether preoperative anemia and iron deficiency impact short-term recovery.MethodsThis retrospective cohort study included 262 patients with AOC who underwent surgery at Skane University

Short-Term Bienenstock-Cooper-Munro Learning in Optoelectrically-Driven Flexible Halide Perovskite Single Crystal Memristors

The transition to smart, wearable, and flexible optoelectronic devices that communicate with each other and perform neuromorphic computing at the edge, is a major goal in next-generation optoelectronics. These devices are expected to carry out their regular tasks while being supported by energy-efficient, in-memory computations. In this study, a lateral flexible device based on cesium lead tribrom

Interfaces in Epitaxially Grown Zn3P2 Nanowires and Their Composition-Dependent Optoelectronic Properties for Photovoltaic Applications

Epitaxially grown nanowires have shown promise for photovoltaic applications due to their nanophotonic properties. Moreover, the mechanical properties of nanowires can reduce crystallographic defect formation at interfaces to help enable new material combinations for photovoltaics. One material that stands to benefit from the nanowire morphology is zinc phosphide (Zn3P2), which, despite promising

Medial plica is associated with progression of medial meniscus extrusion in middle-aged persons with Kellgren–Lawrence grade 0 : data from the osteoarthritis initiative

Background: Medial plica is a structure with limited understanding of its pathology, but it may be related to the development of medial knee osteoarthritis (OA). We examined the association between medial plica and medial meniscus extrusion (MME), progression of MME, and the risk of early-stage knee OA development in middle-aged persons. Methods: A total of 340 subjects with tibiofemoral Kellgren–

Prevalence and common cardiovascular risk factors in aortic valve calcification in the middle-aged general population

Aims Aortic valve calcification (AVC) is an underlying pathophysiological mechanism for aortic stenosis that is common in the elderly, but less is known in younger individuals. The aim was to study the prevalence and associated characteristics of AVC in a middle-aged general population. Methods and results Data were obtained from the Swedish CArdioPulmonary bioImage Study (SCAPIS) comprising 30 15