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Perspectives on Care for Late-Stage Parkinson's Disease

In the late stage of Parkinson's disease (PD), there is an increasing disease burden not only for the patients but also for their informal caregivers and the health and social services systems. The aim of this study was to explore experiences of late-stage PD patients' and their informal caregivers' satisfaction with care and support, in order to better understand how they perceive the treatment a

The Calcium Channel Subunit Gamma-4 as a Novel Regulator of MafA in Pancreatic Beta-Cell Controls Glucose Homeostasis

Impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) are high-risk factors of diabetes development and may be caused by defective insulin secretion in pancreatic beta-cells. Glucose-stimulated insulin secretion is mediated by voltage-gated Ca2+ (CaV) channels in which the gamma-4 subunit (CaVγ4) is required for the beta-cell to maintain its differentiated state. We here aim to explo

Transcriptomic analysis of functional diversity of human umbilical cord blood hematopoietic stem/progenitor cells in erythroid differentiation

Hematopoietic stem cells (HSC) give rise to all types of blood lineages, including red blood cells (RBC). Hematopoietic stem/progenitor cells (HSPC) are known to be functionally diverse in terms of their self-renewal potential and lineage output. Consequently, investigation of molecular heterogeneity in the differentiation potential of HSPC is vital to identify novel regulators that affect generat

Impact of the first wave of the COVID-19 pandemic on healthcare use in osteoarthritis : A population register-based study in Sweden

Objective: To investigate whether the first wave of the COVID-19 pandemic impacted healthcare consultations (HCC) and hospitalization among people with and without osteoarthritis (OA).Methods: Using register data, we included individuals aged ≥35 years residing in Skåne region, Sweden, during 2009-2019 with (n ​= ​123,523) and without (n ​= ​552,412) a diagnosis of OA during January 1, 2009-Decemb

Performance and wear mechanisms of different PcBN tools when machining superalloy AD730

Nickel-based superalloys are known to be difficult to machine. These alloys are generally machined with cemented carbide tools under low productivity process conditions. Superhard polycrystalline cubic boron nitride (PcBN) tooling offers the possibility of increased production rates, however, a thorough understanding of the material performance and degradation is required before a transition from

Tolerance of metal halide perovskites to mechanical treatment enables the fabrication of patterned luminescence nano- and microstructures

Metal halide perovskites have shown a great performance in a broad range of optoelectronic devices. The variety of preparation methods makes perovskites especially attractive, yet preparation of complex nanostructures based on these materials remains challenging. Here we present a template assisted method allowing to achieve any pre-designed arrangement of methylammonium lead triiodide (MAPbI3) po

An aggregation inhibitor specific to oligomeric intermediates of Aβ42 derived from phage display libraries of stable, small proteins

The self-assembly of amyloid β peptide (Aβ) to fibrillar and oligomeric aggregates is linked to Alzheimer’s disease. Aβ binders may serve as inhibitors of aggregation to prevent the generation of neurotoxic species and for the detection of Aβ species. A particular challenge involves finding binders to on-pathway oligomers given their transient nature. Here we construct two phage–display libraries

Comparison of particle number size distribution trends in ground measurements and climate models

Despite a large number of studies, out of all drivers of radiative forcing, the effect of aerosols has the largest uncertainty in global climate model radiative forcing estimates. There have been studies of aerosol optical properties in climate models, but the effects of particle number size distribution need a more thorough inspection. We investigated the trends and seasonality of particle number

Role of solution concentration in formation kinetics of bromide perovskite thin films during spin-coating monitored by optical in situ metrology

Optoelectronic devices based on metal halide perovskites continue to show a improved performance, and solution-based coating techniques pave the way for large-area applications. However, not all parameters influencing the thin film formation process of metal halide perovskites are identified and entirely rationalised over their full compositional range, thus hampering optimised thin film fabricati

Microscopic model of spin flip-flop processes in crystals doped by rare-earth ions

Flip-flop processes due to magnetic dipole-dipole interaction between neighboring ions in crystals doped by rare-earth ions are one of the mechanisms of relaxation between hyperfine levels. Modeling of this mechanism has so far been macroscopic, characterized by an average rate describing the relaxation of all ions. Here, however, we present a microscopic model of flip-flop interactions between in

Exploring Factors Causing Disparity between Desired and Experienced Effects of Campus ERP Systems

Enterprise Resource Planning (ERP) systems have been used by organizations and companies the world throughout since 1990. Many universities have recently replaced their legacy systems with ERP systems to improve work efficiency. One solution available for universities by way of management information system is the Campus ERP system. The Campus ERP system helps universities incorporate all departme

Nämndemannasystemet ur ett rättssäkerhetsperspektiv

The focus of my thesis has been the Swedish lay judges. My purpose has been to examine the Swedish system of lay judges and furthermore study it in relation to legal certainty. My major problem statement has been: In accordance with legal certainty, what advantages and disadvantages can be seen with the system of lay judges? The Swedish lay judges participate primarily in district and appellate c

Immunity of Former High Ranking State Officials for International Crimes before Foreign National Courts

The purpose of the thesis is to examine to what extent former high ranking state officials are immune for international crimes before foreign national courts. Historically national courts have recognized absolute immunity, but this approach has gradually to some extent changed after the establishment of international tribunals and the International Criminal Court in which official capacity is irre

Yes we can - stop keystone pipeline

The aim of this thesis is to gather an understanding of the creation of unlikely alliances within the environmental movement as a social movement. This is done in turn done by looking at the resistance among the environmental movement as well as grassroots organizations that arose around the proposal to build a pipeline called Keystone XL made by the Canadian oil company TransCanada in 2008. The f

Too many calories, too few nutrients? : a systems approach to food and nutrition security in Guatemala

Obesity levels in developing countries are increasing at an alarming rate, while “old” problems such as hunger and undernutrition still persist, creating a paradoxical situation of a double burden of malnutrition. Intertwined with new sustainability challenges such as climate change and land degradation, food, health and sustainability are interconnected in a complex web of relationships, spanning

Reseavdrag och miljöpolitik

Reseavdraget – Motverkar det politiska spelet incitament som kan förbättra miljön? Reseavdraget, att vara berättigad till att dra av en del av kostnaderna som uppkommer till följd av resor till och från arbetsplatsen på skatten, har förundrat mig under flera år. Är reseavdraget rättvist utformat, belönar det ett samhällsekonomiskt olönsamt val eller kan det skapa incitament för arbetspendlare attIncome Tax-deduction for commuting expenses has been criticised and discussed for a long time without having reached any conclusions or reformations. Critical opinions in the debate are that a reformation would disfavour taxpayers living in the countryside with no options except car commuting and decreasing size of labour market regions. At the same time tax evasion is a huge problem because taxpa

UN vs OECD Model Tax Conventions - An alternative for development through formulary apportionment?

The purpose of this thesis is to evaluate the compatibility of the current dominant approach in international taxation for intragroup transactions, based on arm’s length principle, with international agreements on development. In this sense, the thesis aims to explore the viability of formulary apportionment as an alternative that could reduce contradictions between international tax law and devel

2015 vt konferens1

Microsoft Word - 2015 vt konferens[1].docx Konferens i Rättssociologi Välkomna till rättssociologistudenternas avslutande konferens Program den 17 mars 2015 Plats: LUX, nedre Tid: 9.30- 15.00   2   PROGRAM   SÄKERHET  VID  KRIMINALVÅRDEN   3   kl.  9.30-­‐10.00   EN  EVENTUELL  LEGALISERING  AV  SURROGATMÖDRASKAP   4   kl.  10.00-­‐10.30   KVINNORNA  I  IS   4   kl.  10.30-­‐11.00   LEXBASE   6  

https://www.soclaw.lu.se/sites/soclaw.lu.se/files/2015_vt_konferens1.pdf - 2026-05-19