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Mangroves, as unique coastal wetlands with numerous benefits, are endangered mainly due to the coupled effects of anthropogenic activities and climate change. Therefore, acquiring reliable and up-to-date information about these ecosystems is vital for their conservation and sustainable blue carbon development. In this regard, the joint use of remote sensing data and machine learning algorithms can
BACKGROUND: Women living in the Bolivian Andes are environmentally exposed to arsenic, yet there is scarce information about arsenic-related effects in this region. Several biomarkers for telomere length and oxidative stress (mitochondrial DNA copy number, mtDNAcn; 8-Oxo-2'-deoxyguanosine, 8-oxo-dG; and 4-hydroxy nonenal mercapturic acid, 4-HNE-MA) have been previously linked to arsenic, and some
Metastatic castration-resistant prostate cancer is today incurable. Conventional imaging methods have limited detection, affecting their ability to give an accurate outcome prognosis, and current therapies for metastatic prostate cancer are insufficient. This inevitably leads to patients relapsing with castration-resistant prostate cancer. Targeting prostate-specific antigens whose expression is c
The EU’s fiscal rules, set out in the Maastricht Treaty of 1993 and the Stability and Growth Pact of 1997, are anchored to GDP. The debt ceiling and the deficit threshold are set to 60 percent and 3 percent of GDP, respectively. Recently, prominent economists and policymakers, have argued that that the debt ceiling should be raised due to falling bond yields. By extension, this argument suggests a
Governmental policies and business models are considered key elements for a transition to a circular economy. In current literature, there is a lack of understanding on how these two elements interact and how this understanding is used to accelerate the realisation of a circular economy. We shed light on this issue by conducting a systematic review of the literature in combination with a literatur
Background: Although housing accessibility is associated with important health outcomes in other populations, few studies have addressed this in a Parkinson’s disease population. Aim: To determine the most severe environmental barriers in terms of housing accessibility problems and how these evolved over 3 years among people with Parkinson’s disease. Material and Methods: 138 participants were inc
Within the grand sandstone quarries of Gebel el-Silsila is a vast amount of unique symbolic representations; stylized iconographic and pseudo-scripted signs and marks that to some extent signify deities and their protection against demons, evil and mishaps. Like written protective formulae, these marks were placed within the quarries to symbolically safe-keep the quarry workers, and for expressing
The development of process parameters and scanning strategies for bulk metallic glass formation during additive manufacturing is time-consuming and costly. It typically involves trials with varying settings and destructive testing to evaluate the final phase structure of the experimental samples. In this study, we present an alternative method by modelling to predict the influence of the process p
BACKGROUND: Phaeochromocytoma is sometimes not diagnosed before surgery and may present as an adrenal incidentaloma. The aim of this study was to investigate differences in clinical presentation and perioperative outcome in patients with subclinical and symptomatic phaeochromocytoma, and in patients operated with and without preoperative α-blockade. METHODS: This was a retrospective observational
Unlike misfolding in neurodegenerative diseases, aggregation of functional amyloids involved in bacterial biofilm, e.g. CsgA (E. coli) and FapC (Pseudomonas), is carefully regulated. However, it is unclear whether functional aggregation is inhibited by chaperones targeting pathological misfolding and if so by what mechanism. Here we analyze how four entirely different human chaperones or protein m
A system we denote Seg2Pose is presented which converts pixel coordinate tracks, represented by instance segmentation masks across multiple video frames, into world coordinate pose tracks, for road users seen by static surveillance cameras. The road users are bound to a ground surface represented by a number of 3D points and does not necessarily have to be perfectly flat. The system works with one
Transport energy conservation research in urban transport systems dates back principally to the Organization of the Petroleum Exporting Countries’ (OPEC) “Arab Oil Embargo” (1973–1974) and the Iranian revolution (1979), when global oil supplies became threatened and costs rose steeply. Two subsequent Gulf Wars (1991 and 2003) highlighted the dangerous geo-political dimensions of Middle-Eastern oil
Estimation or measurement of glomerular filtration rate (GFR) is generally required for optimal treatment of patients. Plasma creatinine has been used for estimation of GFR since 1926 and plasma cystatin C since 1979. The creatinine level is strongly dependent upon muscle mass and as the average muscle mass of dif- ferent populations may vary, creatinine-based GFR-estimating equations have since 1
The electrification of road bound transport is to some extent limited by the large cost of the energy storage required on-board the vehicles, i.e., the cost of the battery. One way of reducing the required capacity of the on-board energy storage is to enable the possibility to supply the vehicles with electrical energy while it is moving, also called dynamic charging. The energy transfer is usuall
PURPOSE: To compare two aflibercept treatment regimens and the electrophysiological outcome concerning cone and rod function in age-related macular degeneration (nAMD) over 18 months.METHODS: 41 patients with treatment-naïve nAMD were randomized 1:1 to either arm 1 or 2. Arm 1 received three consecutive monthly aflibercept injections, followed by bimonthly treatment until week 52. Thereafter, a tr
We present a novel, global 30 arc seconds (∼1 km at the equator) population projection dataset covering each year from 2010 to 2100 that is consistent with both country level population and gridded urban fractions from the Coupled Model Intercomparison Project 6 (CMIP6). While IPCC population projections until 2100 are available at country level for Socio-Economic Pathways (SSPs), land cover (incl
p53 is a transcription factor that participates in cell cycle checkpoint processes and apoptosis. The protein product of the murine double minute gene 2 (mdm-2) plays a central role in the regulation of p53. In response to DNA-damaging agents, the wild-type p53-activated fragment 1 (WAF1 also known as p21) is an important downstream effector in the p53-specific growth arrest pathway. In breast can
The retail sector is facing fundamental transformations in nearly every part of the value chain, affecting the need for competence development in many retail professions. As most learning at work is informal and there is a deficit of studies of how such learning takes place in specific professions, systematized work with competence development is hampered. We therefore investigated the informal le
