Filetype
The current study empirically demonstrates the widely discussed gap between copyright law and social norms. Theoretically founded in the sociology of law, the study uses a well-defined concept of norms to quantitatively measure changes in the strength of social norms before and after the implementation of legislation. The ‘IPRED law’ was implemented in Sweden on 1 April 2009, as a result of the EU
Strategies for expanding hematopoietic stem cells (HSCs) include coculture with cells that recapitulate their natural microenvironment, such as bone marrow stromal stem/progenitor cells (BMSCs). Plastic-adherent BMSCs may be insufficient to preserve primitive HSCs. Here, we describe a method of isolating and culturing human BMSCs as nonadherent mesenchymal spheres. Human mesenspheres were derived
Hydrogen energy plays a pivotal role in the sustainable energy transition. Methanol steam reforming offers an efficient route for decentralized hydrogen production, yet catalyst limitations persist. This work employs entropy engineering to design lanthanide perovskite catalysts via sol-gel synthesis. Structural analyses reveal entropy-driven lattice distortion, enhanced disorder, and elevated oxyg
Using a mixed-methods approach, we assessed understanding of risks from exposure to the non-threshold carcinogen hexavalent chromium (Cr(VI)) among workers (n = 113) and occupational health and safety managers (n = 13) at 14 worksites with potential exposure to Cr(VI). We found that 55% of the workers had a measurable concentration of inhalable Cr(VI), with 19% exceeding 1 µg/m3, a level that corr
Background: Gaming disorder is a recently recognized psychiatric condition and a growing public health concern, particularly among adolescents. Despite this, there is limited research on what kind of treatment they need. Existing studies are mostly quantitative and offer limited insight into adolescents' lived experiences.Aim: The aim of this qualitative study is to explore how adolescent patientsBackground: Gaming disorder is a recently recognized psychiatric condition and a growing public health concern, particularly among adolescents. Despite this, there is limited research on what kind of treatment they need. Existing studies are mostly quantitative and offer limited insight into adolescents’ lived experiences. Aim: The aim of this qualitative study is to explore how adolescent patient
Climate change is already impacting our environment and health, with rising sea levels, extreme weather, and higher temperatures. Greenhouse gas levels are at their highest in three million years, making climate-related health risks increasingly urgent. Heatwaves, wildfires, and floods lead to mortality, trauma, and non-communicable diseases both in the short and long term. Climate change also alt
We study correlations in the prepare-and-measure scenario when quantum communication is constrained by photon-number statistics. Such constraints are natural and practical control parameters for semi-device-independent certification in optical platforms. To analyse these scenarios, we show how semidefinite programming relaxations for noncommutative polynomial optimization can be used to bound the
Objectives There is a lack of knowledge about whether occupational exposures increase the risk of emphysema, especially in never-smokers. Our objective was to determine if occupational exposures are associated with emphysema and impaired diffusing capacity. Methods In the Swedish CArdioPulmonary bioImage Study (SCAPIS), persons from the general population aged 50–64 answered a questionnaire and un
ORIGINAL ARTICLE Efficient transduction of neurons using Ross River glycoprotein-pseudotyped lentiviral vectors J Jakobsson, T Tolstrup Nielsen, K Staflin, B Georgievska and C Lundberg Department of Experimental Medical Research, Section for Neuroscience, Wallenberg Neuroscience Center, Lund University, Lund, Sweden Lentiviral vectors are promising tools for CNS gene transfer since they efficientl
https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/3302701.pdf - 2026-05-24
doi:10.1016/j.ijmedinf.2006.12.003 i n t e r n a t i o n a l j o u r n a l o f m e d i c a l i n f o r m a t i c s 7 7 ( 2 0 0 8 ) 58–67 journa l homepage: www. int l .e lsev ierhea l th .com/ journa ls / i jmi Trans-Atlantic data harmonization in the classification of medicines and dietary supplements: A challenge for epidemiologic study and clinical research Susan Moyers ∗, Rachel Richesson, Jef
https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_05_moyers_ijmi_2008.pdf - 2026-05-24
Parkinson’s disease (PD) is the most com- mon cause of movement disorder and has a median age-of-onset of ~55 years. It presents with a classical triad of motor symptoms: akinesia, rigidity and tremor. Many patients also suffer from non-motor symptoms, including disturbances of autonomic func- tions and deterioration of cognition1. The aetiology and pathogenetic mechanisms that cause PD remain eni
https://www.wnc.lu.se/sites/wnc.lu.se/files/brundin_et_al_nature_rev_neurosci_2008.pdf - 2026-05-24
Introduction: Observational studies have shown that glycated haemoglobin (HbA(1c)) is related to mortality, but the shape of the association is less clear. Furthermore, disease duration and medication may modify this association. This observational study explored the association between HbA(1c) measured in stored erythrocytes and mortality. Secondly, it was assessed whether disease duration and me
Human bone marrow (BM) contains a rare population of nonhematopoietic mesenchymal stromal cells (MSCs), which are of central importance for the hematopoietic microenvironment. However, the precise phenotypic definition of these cells in adult BM has not yet been reported. In this study, we show that low/negative expression of CD140a (PDGFR-α) on lin(-)/CD45(-)/CD271(+) BM cells identified a cell p
Aims: TCF7L2 variants have been associated with type 2 diabetes, body mass index (BMI), and deficits in proinsulin processing and insulin secretion. Here we sought to test whether these effects were apparent in high-risk individuals and modify treatment responses. Methods: We examined the potential role of the TCF7L2 rs7903146 variant in predicting resistance to weight loss or a lack of improvemen
Purpose The purpose of this study is to better understand online anonymity in the global file-sharing community in the context of social norms and copyright law. The study describes the respondents in terms of use of Virtual Private Networks (VPNs) or similar services with respect to age, gender, geographical location, as well as analysing the correlation with file-sharing frequencies. Design/me
Increased levels of cardio-enriched microRNAs (miRNAs) have been described in patients with myocardial infarction (MI). We wanted to evaluate the diagnostic and prognostic potential of cardio-enriched miRNAs in patients presenting with a suspected acute coronary syndrome (ACS).
Background: Neighborhood walkability has been associated with physical activity in several studies. However, as environmental correlates of physical activity may be context specific, walkability parameters need to be investigated separately in various countries and contexts. Furthermore, the mechanisms by which walkability affects physical activity have been less investigated. Based on previous re
The association between exposure to perfluorinated compounds (PFCs) and attention deficit hyperactivity disorder (ADHD) diagnosis has been sparsely investigated in humans and the findings are inconsistent.
Background: Overweight and obesity during pregnancy raise the risk of gestational diabetes and birth complications. Lifestyle factors like physical activity may decrease these risks through beneficial effects on glucose homeostasis. Here we examined physical activity patterns and their relationships with measures of glucose homeostasis in late pregnancy compared to non-pregnant women. Methods: Nor
