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Background & Purpose: Radiation therapy is an essential treatment for cancer patients with the ultimate goal to deliver radiation doses to the tumour with precision while minimizing exposure to surrounding healthy tissues. Treatment verification is crucial to ensure the accuracy of radiation delivery, for instance by measuring the radiation dose distribution. Among various dosimetry techniques
Syftet med denna uppsats är att undersöka hur EU:s reglering av mellanhand-sansvar och de nya processuella skyldigheter som åläggs medieplattformar förhåller sig till det yttrandefrihetsrättsliga skydd som finns i Europakonvent-ionen (EKMR) och EU-stadgan. Uppsatsen innehåller en analys av det grund-läggande skyddet för yttrande- och informationsfriheten som stadgas i artikel 10 EKMR och artikel 1The aim of this study is to examine how the European Union’s regulation of intermediary liability and the new procedural obligations imposed on media platforms relate to the protection of freedom of expression contained in the European Convention on Human Rights (ECHR) and the European Union Charter. The present paper embarks on an analysis of the foundational protection of freedom of expression a
Det har visat sig att fysisk aktivitet minskar risken för en rad olika sjukdomar. Studien syftade till att undersöka fysisk aktivitet i olika kontexter och på olika nivåer för att bidra med ny kunskap om eventuella hälsofördelar med fysisk aktivitet. Då det är betydelsefullt för organisationens effektivitet och produktivitet att de anställda mår bra är det också viktigt att organisationen arbetar Physical activity has been shown to reduce the risk of several illnesses. The study aimed to investigate physical activity in different contexts and on different levels to contribute with new knowledge about possible health benefits linked to physical activity. Since the health of the employees is crucial for the organization’s efficiency and productivity it is important that organizations promote
ABB has identified a potential in decreasing their levels of capital employed and in particular net working capital, NWC. To release tied up capital from the balance sheet, a decision was taken to start an initiative with focus on NWC. The focus area is to reduce NWC as percentage of revenues and to reduce the levels of overdues. The objective of this report is to describe a methodology for decrea
Entreprenadavtal avser i allmänhet omfattande och långvariga arbeten som inbegriper flera olika parter. Det är relativt vanligt förekommande att parterna har olika åsikt gällande hur ett specifikt avtalsvillkor ska tolkas. Det finns ingen entreprenadrättslig lagstiftning. Företrädare för BKK, Byggandets Kontraktskommitté, har framförhandlat standardkontrakt. Standardkontrakten har en stark ställniConstruction contracts generally refer to extensive and long-term projects involving several different parties. It is relatively common for the parties to have different opinions regarding how a specific contractual term should be interpreted. There is no construction contract law in the area. Hereby representatives of the BKK, the Construction Contracts Committee, have negotiated standard contrac
Background and purpose - Childhood fractures are associated with lower peak bone mass (a determinant of osteoporosis in old age) and higher adult fracture risk. By examining time trends in childhood fracture epidemiology, it may be possible to estimate the vector of fragility fracture risk in the future. Patients and methods - By using official inpatient and outpatient data from the county of Skån
Objectives Osteoarthritis (OA) is the most prevalent form of arthritis and accounts for substantial morbidity and disability, particularly in older people. It is characterised by changes in joint structure, including degeneration of the articular cartilage, and its aetiology is multifactorial with a strong postulated genetic component. Methods A meta-analysis was performed of four genome-wide asso
Community screening to guide preventive interventions for acute aortic disease has been recommended in high-risk individuals. We sought to prospectively assess risk factors in the general population for aortic dissection (AD) and severe aneurysmal disease in the thoracic and abdominal aorta.
A method for probing the temporal evolution of ultra-fast carrier generation and recombination processes in wide-bandgap semiconductors, e.g. diamond, is described. Two extreme ultraviolet (pump) pulses produced by high-order harmonic generation in Argon gas (with a photon energy of 32 eV) are superimposed on a sample with a small angle between them, inducing periodic changes in the refractive ind
Approaches exploiting trait distribution extremes may be used to identify loci associated with common traits, but it is unknown whether these loci are generalizable to the broader population. In a genome-wide search for loci associated with the upper versus the lower 5th percentiles of body mass index, height and waist-to-hip ratio, as well as clinical classes of obesity, including up to 263,407 i
Phosphodiesterase-5 (PDE5) inhibitors are suggested to have anti-tumor effects and to inhibit surgery-induced immunosuppression. We aimed to explore whether post-diagnostic use of PDE5 inhibitors was associated with a better prognosis among male patients with colorectal cancer (CRC) and the role of open surgery in the association. Here we show that post-diagnostic use of PDE5 inhibitors is associa
Background: Nine mRNA transcripts associated with acute cellular rejection (ACR) in previous microarray studies were ported to the clinically amenable NanoString nCounter platform. Here we report the diagnostic performance of the resulting blood test to exclude ACR in heart allograft recipients: HEARTBiT. Methods: Blood samples for transcriptomic profiling were collected during routine post-transp
Recent advances in high-throughput sequencing technologies uncovered widespread RNA modifications on coding and non-coding RNAs collectively refer to as the epitranscriptome. However, we are only now starting to appreciate the impact of the epitranscriptome in regulating cell biology. Among more than 150 RNA modifications, I focused on pseudouridine (Ψ) the most abundant single-nucleoside RNA modi
The ability of new neurons to promote repair of brain circuitry depends on their capacity to re-establish afferent and efferent connections with the host. In this review article, we give an overview of past and current efforts to restore damaged connectivity in the adult mammalian brain using implants of fetal neuroblasts or stem cell-derived neuronal precursors, with a focus on strategies aimed t
