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Resolving the genetic basis of complex diseases like rheumatoid arthritis will require knowledge of the corresponding diseases in experimental animals to enable translational functional studies. Mapping of quantitative trait loci in mouse models of arthritis, such as collagen-induced arthritis (CIA), using F-2 crosses has been successful, but can resolve loci only to large chromosomal regions. Usi

To develop an innovative information and communication technology (ICT) tool intended to help older people in their search for optimal housing solutions, a first step in the development process is to gain knowledge from the intended users. Thus the aim of this study was to deepen the knowledge about needs and expectations about housing options as expressed and prioritized by older people, people a

Context. The Milky Way nuclear star cluster (MWNSC) is located in the Galactic centre, together with the Milky Way nuclear stellar disc (MWNSD), and they dominate the gravitational potential within the inner 300 pc. However, the formation and evolution of the two systems and their possible connections are still under debate. Aims. We reanalysed the low-resolution KMOS spectra in the MWNSC with the

Background: Approximately 15% of Canadian adults live with two or more chronic diseases, many of which are obesity related. The degree to which Canadian obesity treatment guidelines are integrated into chronic disease management is unknown. Methods: We conducted a 12-min online survey among a non-probability sample of 2506 adult Canadians who met at least one of the following criteria: 1) BMI ≥30

Background and aim: Repeat hepatectomy is increasingly performed for the management of recurrent colorectal liver metastases (CRLM). The aim of this study was to evaluate longterm functional liver volume (FLV) after a second hepatic procedure and to measure survival outcome. Methods: In this retrospective cohort study, patients treated for recurrent CRLM in the years 2005-2015 at two liver centers

BackgroundThere is a need for the development of accurate, accessible and efficient screening instruments, focused on early-stage detection of neurocognitive disorders. The Geras Solutions cognitive test (GSCT) has showed potential as a digital screening tool for cognitive impairment but normative data are needed.ObjectiveThe aim of this study was to obtain normative data for the GSCT in cognitive

The Parkinson's disease (PD) home diary is frequently used in clinical trials to measure efficacy of medical treatments for motor fluctuations in advanced PD. This prospective study in fluctuating PD patients examines the validity of the diary for quantification of motor states in comparison to direct clinical observation. 51 patients (median age: 65 years, disease duration: 11 years) completed th

The implementation of circular initiatives requires certain capabilities and knowledge that traditional business models often lack, requiring new perspectives and external collaborations. This paper explores the competency needs and partnership dynamics of established companies collaborating for business model innovation for circularity through a case study of a gap exploiter business model, a com

Jonason och Webster (2011) fann att narcissism är relaterat till särskilda taktiker för att påverka andra människors beteenden. Denna studie undersöker det omvända förhållandet: vad lockar narcissister att hjälpa andra? 41 studenter fyllde i Narcissistic Personality Inventory (NPI; Raskin & Terry, 1988), varpå de tittade på ett videoklipp föreställande en person som tyst tittar in i kameran. D

Ett patent är en immateriell rättighet som medför en ensamrätt för patenthavaren att dra affärsmässig nytta av en viss uppfinning under en begränsad tidsperiod. Den som kränker patenthavarens ensamrätt gör sig skyldig till patentintrång. Vid patentintrång tillhandahåller den svenska patentlagen (1967:837) ett antal olika sanktionsmöjligheter. De primära civilrättsliga sanktionsformerna utgörs av pA patent is a kind of intellectual property right that grants the patent holder an exclusive right to profit from a certain invention for a limited time period. Anyone who violates the patent holder's exclusive right is guilty of patent infringement. In cases of patent infringement the Swedish Patent Act (patentlag 1967: 837) provides a number of different sanction options. The primary civil s

Due to the world becoming increasingly more ambiguous and uncertain, some concepts may consequently become more relevant when evaluating ways to cope with this change. One such concept that has historical indications of being a significant factor in people’s ability to successfully cope with a changing environment is what is called the need for closure. Developed and researched by Arie W. Kruglans

Syftet med denna uppsats är att utreda vilka motiv fastighetsföretag har med sina avskrivningar. Studien undersöker vilka överväganden som kan behöva göras för att upprätthålla dessa motiv vid övergången till K3 och komponentavskrivningar. Studien är genomförd utifrån kvalitativ forskningsmetod. Som en del av den kvalitativa metoden har vi genomfört intervjuer med ekonomiansvariga på fastighetsför

The Danish scholar Johannes Munck proposed a connection between Paul's collection for Jerusalem and prophetic texts that envisage a pilgrimage of Gentiles to Zion in the end times. Nonetheless, Munck's seminal theory on the collection for Jerusalem has been contested in recent times. This article argues that the Pauline Epistles contain some textual evidence of this link between the two events and

Iridium dioxide (IrO2), ruthenium dioxide (RuO2), and their solid solutions (Ir1-xRuxO2) are very active electrocatalysts for the oxygen evolution reaction (OER). Efficient and facile synthesis of nanosized crystallites of these materials is of high significance for electrocatalytic applications for converting green energy to fuels (power-to-X). Here, we use in situ X-ray scattering to examine rea

Introduction: Airway management is a critical component of out-of-hospital cardiac arrest (OHCA) resuscitation. The primary aim of this study was to describe pre-hospital airway management in adult patients post-OHCA. Secondary aims were to investigate whether tracheal intubation (TI) versus use of supraglottic airway device (SGA) was associated with patients’ outcomes, including ventilator-free d