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Background & aims: We have previously reported that the serum levels of gut-derived tryptophan metabolite indole-3-propionic acid (IPA) are lower in individuals with liver fibrosis. Now, we explored the transcriptome and DNA methylome associated with serum IPA levels in human liver from obese individuals together with IPA effects on shifting the hepatic stellate cell (HSC) phenotype to inactiv
Random access codes are a type of communication task that is widely used in quantum information science. The optimal average success probability that can be achieved through classical strategies is known for any random access code. However, only a few cases are solved exactly for quantum random access codes. In this paper, we provide bounds for the fully general setting of n independent variables,
Shared entanglement can significantly amplify classical correlations between systems interacting over a limited quantum channel. A natural avenue is to use entanglement of the same dimension as the channel because this allows for unitary encodings, which preserve global coherence until a measurement is performed. Contrasting this, a distributed task based on a qubit channel is demonstrated, for wh
BACKGROUND: Insufficient knowledge among assistant nurses (ANs) in nursing homes (NHs) on medicines and drug-related problems (DRPs) in older people causes difficulties in acknowledging the side effects of medications, which can be harmful to the individual and endangers patient safety. The aim of this study was to explore the ANs' thoughts on their professional role in preventing DRPs in NH resid
The quantum prepare-and-measure scenario has been studied under various physical assumptions on the emitted states. Here, we first discuss how different assumptions are conceptually and formally related. We then identify one that can serve as a relaxation of all others, corresponding to a limitation on the one-shot accessible information of the state ensemble. This motivates us to study the optima
Background: Psychiatric disorders have been associated with venous thromboembolism (VTE). However, to our knowledge, no nationwide study has examined the familial association between VTE and psychiatric disorders. Objectives: We took a pedigree-based approach and examined the risk of psychiatric disorders in offspring from extended pedigrees according to the densities of VTE in pedigrees. Methods:
Background: Community-acquired pneumonia (CAP) was one of the most common causes of death in the European Union in 2017. Severity and mortality of CAP increase with age and an aging European population will require increased planning for prevention, control, and management of CAP. The purpose of this study was to provide an updated population-based estimate of the incidence of CAP requiring hospit
Background: The aging of the world’s population and the increase in sedentary lifestyles are leading to an increase in walking impairments at older ages. Here, we aimed to comprehensively discuss walking in the context of an aging population; and identify and agree on a list of future research priorities and policy actions. Methods: We followed a participatory approach and held a multidisciplinary
The modern food industry faces the challenge of catering to diverse consumer preferences while maintaining efficiency and profitability. Rapid shifts in consumer trends, emerging technologies, and evolving regulations make it difficult for companies to keep pace, often resulting in inefficiencies and lost opportunities. The vast amount of data generated across production, supply chains, and market
PURPOSE: This observational study examined the relationship between self-reported dietary patterns-omnivore, pescatarian, vegetarian, and vegan-and iron status among Swedish teenage girls. Additionally, we compared the consumption of various food groups in relation to iron status.METHODS: Data were collected from 475 female high school students in Malmö and Lund, Sweden, using questionnaires on di
This paper deals with numerical investigations of cross laminated timber (CLT) beams. Previous investigations have revealed discrepancies between experimental test results and suggested design methods regarding shear force capacity of such beams. To gain further understanding of the failure behaviour and the shear force capacity, nonlinear finite element analyses have been performed, using a cohes
We show that bipartite bound entangled states make possible violations of correlation inequalities in the prepare-and-measure scenario. These inequalities are satisfied by all classical models as well as by all quantum models that do not feature entanglement. In contrast to the known Bell inequality violations from bound entangled states, we find that the violations in the prepare-and-measure scen
The statistics of transmitted photons in microwave cavities play a foundational role in microwave quantum optics and its technological applications. By utilizing quantum mechanical phase-space methods, we here develop a general theory of the photon counting statistics in Gaussian bosonic networks consisting of driven cavities with beamsplitter interactions and two-mode-squeezing. The dynamics of t
High-dimensional systems are an important frontier for photonic quantum correlation experiments. These correlation tests commonly prescribe measurements with many possible outcomes but they are often implemented through many individual binary-outcome measurements that use only a single-detector. Here, we discuss how this binarization procedure for multioutcome measurements can open a loophole, unl
Synthesis of molecularly imprinted polymer microspheres using precipitation polymerization was first reported in 1999 in Lund. The synthetic approach attracted great interest for molecular imprinters worldwide due to its simplicity. Following the initial demonstration of feasibility for material synthesis, imprinted polymer microspheres were found to exhibit good colloidal stability qualifying for
Objective To date, the major pathways contributing to cardiovascular disease among night shift workers remain poorly understood. MicroRNAs (miRNAs) have been identified as novel regulators of cardiovascular risk factors and are estimated to control more than 30 candidate miRNAs among night shift workers.Materials and Methods RNA was extracted from plasma samples of 110 night and 90day shift worker
Objectives: Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) libraries have limited capabilities for identification of Streptococcus bovis/Streptococcus equinus-complex (SBSEC) subspecies. The objective was to develop and validate novel MALDI-TOF MS libraries adapted to diagnostic culturing and sampling conditions for improved identification of SBSEC subs
A common type of inhalation medicine uses a dry powder formulation where the active pharmaceutical ingredient (API) is attached on the surface of carrier particles, often in combination with additional components. The spatial distribution of the API on the carrier particle is critical for the release into the lungs and thus for the efficacy of the drug. In this work, we use ToF-SIMS imaging in com
