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Molecular Epidemiology and Transmission Dynamics of the HIV-1 Epidemic in Ethiopia : Epidemic Decline Coincided With Behavioral Interventions Before ART Scale-Up

Background: Ethiopia is one of the sub-Saharan countries hit hard by the HIV epidemic. Previous studies have shown that subtype C dominates the Ethiopian HIV-1 epidemic, but the evolutionary and temporal dynamics of HIV-1 in Ethiopia have not been closely scrutinized. Understanding the evolutionary and epidemiological pattern of HIV is vital to monitor the spread, evaluate and implement HIV preven

Experimental Verification of the Work Fluctuation-Dissipation Relation for Information-to-Work Conversion

We study experimentally work fluctuations in a Szilard engine that extracts work from information encoded as the occupancy of an electron level in a semiconductor quantum dot. We show that as the average work extracted per bit of information increases toward the Landauer limit Formula Presented, the work fluctuations decrease in accordance with the work fluctuation-dissipation relation. We compare

Religious service attendance and mortality: A population-based prospective cohort study in southern Sweden

AimsThe aim is to investigate associations between attendance in religious service during the past year and all-cause, cardiovascular (CVD), cancer and other cause mortality.Study designProspective cohort study.MethodsA public health survey with three reminders was sent to a stratified random sample of the adult 18–80 population in southernmost Sweden in 2008. The response rate was 54.1%, and 24,8

Midnight salivary cortisol secretion associated with high systolic blood pressure in type 1 diabetes

Objective: To explore associations between high midnight salivary cortisol (MSC) secretion and high blood pressure (BP) in type 1 diabetes (T1D). Methods: Cross-sectional study of 196 adult patients with T1D (54% men). Associations between high MSC (≥9.3 nmol/L) and high systolic BP (>130 mmHg), and high diastolic BP (>80 mmHg) were explored for all patients, users and non-users of antihypertensiv

Second asymptomatic carotid surgery trial (ACST-2) : a randomised comparison of carotid artery stenting versus carotid endarterectomy

BACKGROUND: Among asymptomatic patients with severe carotid artery stenosis but no recent stroke or transient cerebral ischaemia, either carotid artery stenting (CAS) or carotid endarterectomy (CEA) can restore patency and reduce long-term stroke risks. However, from recent national registry data, each option causes about 1% procedural risk of disabling stroke or death. Comparison of their long-te

Association of Circulating Long Noncoding 7S RNA with Deep Vein Thrombosis

Mitochondrial dysfunction is a recognized factor in the pathogenesis of deep vein thrombosis (DVT). The role of 7S RNA, a long noncoding RNA that plays an important role in mitochondrial function, in DVT remains unclear. In this study, we aimed to investigate the potential use of 7S RNA as a biomarker in DVT. Plasma samples were obtained from 237 patients (aged 16-95 years) with suspected DVT recr

A EUFOREA comment on a lost comorbidity of asthma

“Epidemiology of comorbidities and their association with asthma control” (Tomisa, G., Horváth, A., Sánta, B. et al. Epidemiology of comorbidities and their association with asthma control. Allergy Asthma Clin Immunol 17, 95 (2021). https://doi.org/10.1186/s13223-021-00598-3) is an interesting paper reflecting data collection from more than 12,000 asthmatic patients in Hungary regarding their cond

Comorbidity in incident osteoarthritis cases and matched controls using electronic health record data

Background: Comorbidities are common in patients with osteoarthritis (OA). This study aimed to determine the association of a wide range of previously diagnosed comorbidities in adults with newly diagnosed OA compared with matched controls without OA. Methods: A case–control study was conducted. The data were derived from an electronic health record database that contains the medical records of pa

Leisure-time physical activity, desire to increase physical activity, and mortality : A population-based prospective cohort study

The aim was to investigate associations between leisure-time physical activity (LTPA) and mortality, and associations between desire to increase LTPA and mortality within the low LTPA group. A public health survey questionnaire was sent in 2008 to a stratified random sample of the population aged 18-80 in southernmost Sweden, yielding a 54.1% response rate. Baseline 2008 survey data with 25,464 re

Mental distress in relation to police reporting among adolescent victims of robbery : A population-based study in southern Sweden

•Robberies as well as mental distress have increased among adolescents in Sweden.•This study on school students in southern Sweden was population-based with a high response rate.•Half of the robbed adolescents abstained from police reporting.•Non-reporters had poorer mental health than victims who reported the robbery.•Non-reporters were also an overall more disadvantaged group.

Understanding the urban ecosystem : interactions between plants, animals, and people

Cities are the pinnacle of human change to the environment, creating unique types of ecosystems which present many challenges to local organisms: habitat fragmentation, introduced species, and various pollutants. Being crucibles of anthropogenic effects, urban ecosystems offer opportunities to understand how humans impact nature. Moreover, since a majority of the world’s population resides in citiCities are the pinnacle of human change to the environment, creating unique types of ecosystems which present many challenges to local organisms: habitat fragmentation, introduced species, and various pollutants. Being crucibles of anthropogenic effects, urban ecosystems offer opportunities to understand how humans impact nature. Moreover, since a majority of the world’s population resides in citi

Trust in regional politicians and mortality : A population-based prospective cohort study

The aim was to study associations between trust in regional politicians responsible for the healthcare system and mortality in survival analyses. A public health survey in southern Sweden with a 54.1% response rate based on a postal questionnaire and three postal reminders was conducted in 2008. The baseline survey was linked to 8.3-year follow-up all-cause, cardiovascular (CVD), cancer and other

Evaluation of an Injectable Biphasic Calcium Sulfate/Hydroxyapatite Cement for the Augmentation of Fenestrated Pedicle Screws in Osteoporotic Vertebrae : A Biomechanical Cadaver Study

Cement augmentation of pedicle screws is one of the most promising approaches to enhance the anchoring of screws in the osteoporotic spine. To date, there is no ideal cement for pedicle screw augmentation. The purpose of this study was to investigate whether an injectable, bioactive, and degradable calcium sulfate/hydroxyapatite (CaS/HA) cement could increase the maximum pull-out force of pedicle