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Extending the Lund-Malmö creatinine-based GFR equation to cystatin C–validation results from the European Kidney Function Consortium (EKFC) cohort of children and adults

The aim of the present study was to extend the creatinine-based Lund-Malmö GFR equation for use with rescaled cystatin C (r-LMRCys) and validate it against measured GFR (mGFR) in the EKFC cystatin C cohort of children (n = 2,293) and adults (n = 7,727). Rescaling was obtained by dividing each biomarker by a Q-value, representing the population-specific median biomarker level among healthy individu

Internal marketing in changing times - Supporting personnel meeting customers in physical retail stores

Abstract NRWC 2024 Internal marketing in changing times - Supporting personnel meeting customers in physical retail storesUlf Johansson, Lund School of Economics and management, Center for retail studies at Lund universityKristina Bäckström, Campus Helsingborg, Lund university, Center for retail studies at Lund universityA lot has been written about the change of retail in later years (Berman, 201

Clinical significance of a new diagnosis of atrial fibrillation in patients with vascular disease

Background: The Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) trial enrolled patients with vascular disease but excluded patients requiring oral anticoagulation. Objective: We aimed to explore the clinical significance of a new diagnosis of atrial fibrillation (AF) during follow-up. Methods: New AF was identified from hospitalization, study drug discontinuation, and

Prognostic Testing for Prostate Cancer—A Cost-Effectiveness Analysis Comparing a Prostatype P-Score Biomarker Approach to Standard Clinical Practice

Background: The Prostatype score (P-score) is a prognostic biomarker that integrates a three-gene (IGFBP3, F3, and VGLL3) signature derived from prostate biopsy samples, with key clinical parameters, including prostate-specific antigen (PSA) levels, Gleason grade, and tumor stage at diagnosis. The test has demonstrated superior predictive accuracy for prostate cancer outcomes compared with traditi

Sun Exposure and Type 2 Diabetes Mellitus : A Prospective Follow-up Cohort Study from Southern Sweden

Background/Aim: An inverse association exists between type 2 diabetes mellitus (T2DM) and both plasma vitamin D levels and sun exposure, but vitamin D supplementation does not reduce the incidence. We sought to assess whether there is a dose-dependency in the association between sun exposure and T2DM. Patients and Methods: The melanoma in Southern Sweden (MISS) cohort is comprised of one thousand

Successful prevention of organic solvent induced disorders : history and lessons

In this discussion paper, we describe the history of the science and societal action resulting in the mitigation of neurotoxic disorders from exposure to organic solvents at the workplaces in Sweden. When alkyd paints were introduced in large scale in construction painting in the 1960s and 1970s, Scandinavian unions voiced increasing concern as members reported symptoms like headache and vertigo,

Spatiotemporal coupling of attosecond pulses

Attosecond pulses in the extreme ultraviolet (XUV) spectral range are today routinely generated via high-order harmonic generation (HHG), when intense ultrashort laser pulses are focused into a gaseous generation medium. The effect is most easily understood in a semi-classical picture [1]. An electron can tunnel ionize from the distorted atomic potential, pick up kinetic energy in the laser field,

Health locus of control and all-cause, cardiovascular, cancer and other cause mortality : A population-based prospective cohort study in southern Sweden

The aim was to investigate associations between health locus of control (HLC) and all-cause, cardiovascular (CVD), cancer and other cause mortality. A public health postal questionnaire was distributed in the autumn of 2008 to a stratified random sample of the 18–80 year old adult population in Scania in southernmost Sweden. The participation rate was 54.1%, and 25,517 participants were included i

Extreme variation in recombination rate and genetic diversity along the Sylvioidea neo-sex chromosome

Recombination strongly impacts sequence evolution by affecting the extent of linkage and the efficiency of selection. Here, we study recombination over the Z chromosome in great reed warblers (Acrocephalus arundinaceus) using pedigree-based linkage mapping. This species has extended Z and W chromosomes (“neo-sex chromosomes”) formed by a fusion between a part of chromosome 4A and the ancestral sex

Effects of Infant Massage : A Systematic Review

Infant massage is performed in various international contexts. There is a need for an updated literature review on this topic. The purpose of the current review was to investigate the effects of infant massage. A systematic literature review was conducted to investigate the effects of infant massage on the following outcomes: pain relief, jaundice, and weight gain. The inclusion criteria were infa

HIV self-testing for men who have sex with men in Sweden. A cross-sectional study concerning interest to use HIV self-tests

Background: HIV self-testing (HIVST) has been found to have high acceptability among men who have sex with men (MSM) internationally and might contribute to increase testing frequencies, but many countries, including Sweden, lack policies for using HIVST. Objective: To examine interest to use and willingness to pay for HIVST, and associated factors, among MSM attending HIV testing venues in Sweden

Water Chemistry beneath Graphene : Condensation of a Dense OH-H2O Phase under Graphene

Room temperature oxygen hydrogenation below graphene flakes supported by Ir(111) is investigated through a combination of X-ray photoelectron spectroscopy, scanning tunneling microscopy, and density functional theory calculations using an evolutionary search algorithm. We demonstrate how the graphene cover and its doping level can be used to trap and characterize dense mixed O-OH-H2O phases that o

Performance, Analysis, and Modeling of III-V Vertical Nanowire MOSFETs on Si at Higher Voltages

Heterostructure engineering in III-V vertical nanowire (VNW) MOSFETs enables tuning of transconductance and breakdown voltage. In this work, an InxGa 1−x As channel with a Ga-composition grading ( x= 1–0.4) in the channel and drain region, combined with field plate engineering, enables breakdown voltage above 2.5 V, while maintaining transconductance of about 1 mS/ μm , in VNW MOSFETs. The field p

The association between serum estradiol levels and sperm DNA integrity

In men from the general population, BMI has been associated with a lower sperm DNA fragmentation index (DFI). We wondered whether this could be due to estradiol, which is associated with BMI and reported important for sperm function. Our objective was to investigate the association between estradiol and DFI. In 2008–2010, we recruited 284 young men from the general population to deliver samples of

LEVELS OF IL-6 AND OTHER INFLAMMATORY PROTEINS IN EARLY RA PREDICT JOINT DAMAGE PROGRESSION OVER 5 YEARS

Background Joint damage in rheumatoid arthritis (RA) remains a significant problem. Identification of biomarkers associated with joint destruction can improve our understanding of underlying disease processes and future management.Objectives To evaluate inflammatory proteins as potential predictors of radiographic progression of joint damage.Methods Consecutive early RA patients (symptom duration

PREDICTORS OF EROSION AND JOINT SPACE NARROWING PROGRESSION IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS

Background: Joint damage in rheumatoid arthritis (RA) includes erosions and joint space narrowing (JSN). Predictors of these processes, and the underlying mechanisms, require further study1.Objectives: To investigate the relation between patient characteristics at RA diagnosis and progression of erosions and JSN, over 5 years. Methods: Consecutive early RA patients (symptom duration Results: 233 e