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The paper deals with the notion of stability for thermo-elastoplastic materials undergoing large strains. The stability analysis is performed by using the perturbation approach applied to a comprehensive material model derived in a thermodynamic format. As the main contribution of this paper a stability condition for a material model incorporating geometrical and material non-linearities under ful
Creating software tools that address the needs of a wide range of decision-makers requires the inclusion of differing perspectives throughout the development process. Software tools for biodiversity conservation often fall short in this regard, partly because broad decision-maker needs may exceed the toolkits of single research groups or even institutions. We show that participatory, collaborative
High-spin states in 154Dy have been studied using the TESSA2 γ-rays spectrometer following the 110Pd(48Ca,4n)154Dy reaction at a beam energy of 210 MeV. States up to 44+ and 37- have been observed. Below spin 30 the data display regular rotational behaviour which can be interpreted in terms of the cranked shell model. Above spin 30, sequences of levels connected by stretched E2 transitions, which
This paper describes an application of instant messaging to support extended online participatory workshops. We describe the development and application of Participatory Instant Messaging (PIM) within the context of two projects in Sweden, which both aimed to integrate migrant experiences into policy dialogues and societal awareness. The projects brought together artistic practice, research tradit
I en tid när bilder och videor dominerar sociala medieflöden har visuellt material blivit ett av de mest kraftfulla verktygen för att sprida desinformation. Rapporten Bildkunnighet och beredskap visar hur detta skifte förändrar både informationsmiljön och demokratiska förutsättningar. Med generativ AI blir det allt enklare att skapa verklighetstrogna, men helt fabricerade, bilder och filmer vilket
Background: The transient receptor potential melastatin 3 (TRPM3) ion channel has been implicated in sensory modulation and pain transmission and may contribute to migraine pathophysiology through calcitonin gene-related peptide (CGRP) release in the trigeminovascular system. This study aimed to investigate TRPM3 activation and its role in CGRP release, vasodilatory responses, and migraine-relevan
Epileptic seizure prediction holds the potential to enhance the quality of life for individuals with epilepsy by enabling the possibility of timely administration of medication and first aid, as well as preventing subsequent accidents. In this paper, we consider the well-established Heart Rate Variability (HRV) and Lorenz features, and augment them with the electrocardiogram (ECG) multifractality
In this article, I identify a key trend for demarcating the “secular” as a Western, Christian achievement. I analyze how the New Testament story often known as “Render unto Caesar” is referenced as a source for the secular West, particularly in writings by European and American conservative thinkers in the 1990s and early 2000s. My argument is that these references to “Render unto Caesar” constitu
In recent decades, a significant advancement in the Global Navigation Satellite System (GNSS) has been adopting the vector tracking (VT) technique, particularly in environments where stable and reliable positioning is essential. It facilitates rapid reacquisition and continuous tracking of GNSS signals by linking the data processing and signal processing modules. In challenging environments affect
Objectives ‒ Chronic pain is a major global public-health issue. In Sweden, 20% adults report moderate to severe chronic pain, with 7% continuously seeking healthcare. Shortcomings in treatment, accessibility, and knowledge in healthcare for chronic pain have previously been reported. A generic treatment structure from primary to specialized care and rehabilitation was missing. This study aims to
The use of CRISPR-Cas bacterial adaptive immunity system components for targeted DNA changes has opened broad prospects for programmable genome editing of higher organisms. The most widely used gene editors are based on the Cas9 effectors of the type II CRISPR-Cas systems. In complex with guide RNAs, Cas9 proteins are able to directionally introduce double-stranded breaks into DNA regions that are
The electromagnetic performance of the soft magnetic core in manufactured electric machines is known to deviate significantly from datasheet values for the material used in the core. We quantify the discrepancy in permeability and losses between datasheet and physical units by calculating build factors for a typical hairpin IPM traction machine design. The derived build factors for losses are typi
Starting with the lead compound roquinimex, a selection of 3-quinolinecarboxamide derivatives were synthesized and evaluated for the treatment of the autoimmune disease multiple sclerosis. Structure-activity relationships were established in animal studies and from these, laquinimod was chosen as the drug candidate due to its superior potency and toxicological profile as compared to roquinimex. Ho
Additive manufacturing (AM) is revolutionizing industrial production by enabling the fabrication of complex, customized components with reduced material waste. However, the scheduling of AM machines presents significant challenges in terms of optimizing both time-related performance and energy consumption. This paper introduces a novel multi-objective mixed-integer linear programming (MILP) model
Objectives: Studies have reported promising results regarding artificial intelligence (AI) as a tool for improved mammographic screening interpretive performance. We analyzed AI malignancy risk scores from two versions of the same commercial AI model. Materials and methods: This retrospective cohort study used data from 117,709 screening examinations performed in BreastScreen Norway 2009–2018. The
