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Prevalence, trends, and inequality in noncommunicable diseases in Bangladesh : Evidence from Bangladesh Demographic and Health Surveys 2011 and 2017–2018

We investigated the change of the prevalence of noncommunicable diseases (NCDs) in Bangladesh from 2011 to 2018 across different socioeconomic groups as well as the factors associated with the changes in prevalence. We used the two waves of the Bangladesh Demographic and Health Surveys conducted in 2011 and 2017–2018. Modified Poisson regression model was used to estimate the prevalence rate and r

Effects of an interactive web-based support system via mobile phone on preference-based patient participation in patients living with hypertension - a randomized controlled trial in primary care

OBJECTIVE: To estimate the effects of an interactive web-based support system via mobile phone on preference-based patient participation in patients with hypertension treated in primary care (compared with standard hypertensive care only). DESIGN: A parallel group, non-blinded, randomized controlled trial, conducted October 2018-February 2021. Besides standard hypertensive care, the intervention

Reservoir simulation model for the design of irrigation projects

This chapter presents a simulation model for the optimization of a reservoir system that is being developed. Simulation studies were carried out, firstly to determine the best (and by how much) irrigation facilities to provide in the proposed new scheme, and secondly, to see the applicability of simulation in reservoir planning. A computer simulation model using MATLAB has been developed to analyz

Markers of imminent myocardial infarction

Myocardial infarction is a leading cause of death globally but is notoriously difficult to predict. We aimed to identify biomarkers of an imminent first myocardial infarction and design relevant prediction models. Here, we constructed a new case–cohort consortium of 2,018 persons without prior cardiovascular disease from six European cohorts, among whom 420 developed a first myocardial infarction

How can the findings of the EMAX trial on long-acting bronchodilation in chronic obstructive pulmonary disease be applied in the primary care setting?

This review addresses outstanding questions regarding initial pharmacological management of chronic obstructive pulmonary disease (COPD). Optimizing initial treatment improves clinical outcomes in symptomatic patients, including those with low exacerbation risk. Long-acting muscarinic antagonist/long-acting β2-agonist (LAMA/LABA) dual therapy improves lung function versus LAMA or LABA monotherapy,

Recurrence, fidelity and proximity to previously visited sites throughout the annual cycle in a trans-Saharan migrant, the common cuckoo

Most migratory birds return every year to the same breeding sites and some species show a similarly high fidelity to wintering grounds as well. Fidelity to stopover sites during migration has been much less studied and is usually found to be lower. Here, we investigate site fidelity and distance to previously visited sites throughout the annual cycle in the common cuckoo, a nocturnal trans-Saharan

Socio-demographic inequalities influence differences in the chemical exposome among Swedish adolescents

Relatively little is known about the relationship between socio-demographic factors and the chemical exposome in adolescent populations. This knowledge gap hampers global efforts to meet certain UN sustainability goals. The present work addresses this problem in Swedish adolescents by discerning patterns within the chemical exposome and identify demographic groups susceptible to heightened exposur

Longitudinal trajectories of cognitive decline and cerebral blood flow abnormalities in octogenarian men with normal global cognition

Aims: Cognitive and perfusion changes have been previously observed in older men with Mini Mental State Examination scores>24 points. We aimed to investigate time change in cognitive domains in a cohort of non-demented men between age 68 and 82, and how they are expressed in regional defects estimated by Cerebral Blood Flow (rCBF). Methods: 103 men at age 81 with MMSE scores >24 (mean 28.4 ± 1.7),

Associations between daily home blood pressure measurements and self-reports of lifestyle and symptoms in primary care : the PERHIT study

OBJECTIVE: To explore in a primary care setting the associations between patients' daily self-measured blood pressure (BP) during eight weeks and concurrent self-reported values of wellbeing, lifestyle, symptoms, and medication intake. We also explore these associations for men and women separately.DESIGN AND SETTING: The study is a secondary post-hoc analysis of the randomised controlled trial PE

On wear of TiAlN coated tools with and without NbN overlayer in machining titanium alloys

Finding a wear resistant coating for cemented carbide cutting tools in the machining of difficult to cut Ti alloys is a challenge due to their high strength and chemical reactivity. Tool manufacturers recommend physical vapor deposited (PVD) TixAl1-xN (x = 0.4–0.7), and an extra NbN overlayer has shown promising potential. This study explores wear mechanisms of PVD Ti0.45Al0.55N with and without N

Dietary intakes of dioxins and polychlorobiphenyls (PCBs) and mortality : EPIC cohort study in 9 European countries

Dioxins and polychlorinated biphenyls (PCBs) are toxic, endocrine disruptors and persistent chemicals for which the main exposure source is diet due to their bioaccumulation and biomagnification in food chains. Cohort studies in the general populations have reported inconsistent associations between these chemicals in serum/plasma and mortality. Our objective was to study the association between d

Limited beneficial effects of systemic steroids when added to standard of care treatment of seasonal allergic rhinitis

Intramuscular injections with methylprednisolone treating allergic rhinitis (AR) have a long history. Modern guidelines are designed to dissuade this treatment, but it´s frequently used, especially in primary care. This despite of concern for side effects and lack of modern placebo-controlled studies. This study was designed to evaluate if methylprednisolone, could significantly improve symptoms o

Prevalence and prognostic value of electrocardiographic abnormalities in hypokalemia: A multicenter cohort study

AbstractBackgroundHypokalemia is common in hospitalized patients and associated with ECG abnormalities. The prevalence and prognostic value of ECG abnormalities in hypokalemic patients are, however, not well established.MethodsThe study was a multicentered cohort study, including all ault patients with an ECG and potassium level <4.4 mmol/L recorded at arrival to four emergency departments in Denm

Beyond Average : a-Particle Distribution and Dose Heterogeneity in Bone Metastatic Prostate Cancer

a-particle emitters are emerging as a potent modality for disseminated cancer therapy because of their high linear energy transfer and localized absorbed dose profile. Despite great interest and pharmaceutical development, there is scant information on the distribution of these agents at the scale of the a-particle pathlength. We sought to determine the distribution of clinically approved [223Ra]R

Monkeypox virus-associated meningoencephalitis diagnosed by detection of intrathecal antibody production

Background: In the 2022 mpox-outbreak most patients presented with mild symptoms. Central nervous system (CNS) involvement has previously been described as a rare and severe complication of mpox; however, diagnostic findings in cerebrospinal fluid (CSF) analysis and neuroimaging studies have only been reported in one case previously. Case presentation: We report a previously healthy 37-year-old ma

Design of flexible lattice structures : a design for additive manufacturing perspective

Recent years has seen an unprecedented growth in emerging technologies like Additive manufacturing (AM), augmenting the manufacturing capabilities through a multitude of opportunities while also introducing unique constraints, such as support structures, and post-processing requirements. Taking full advantage of the potential of AM demands product designs to be optimised for both opportunities and

Pulmonary delivery systems for antimicrobial peptides

Bacterial infections of the respiratory tract cause millions of deaths annually. Several diseases exist wherein (1) bacterial infection is the main cause of disease (e.g., tuberculosis and bacterial pneumonia), (2) bacterial infection is a consequence of disease and worsens the disease prognosis (e.g., cystic fibrosis), and (3) bacteria-triggered inflammation propagates the disease (e.g., chronic

Patient reported symptoms and disabilities before and after neuroma surgery : a register-based study

Residual problems may occur from neuroma despite surgery. In a 12-month follow-up study using national register data, symptoms, and disabilities related to surgical methods and sex were evaluated in patients surgically treated for a neuroma. Among 196 identified patients (55% men; lower age; preoperative response rate 20%), neurolysis for nerve tethering/scar formation was the most used surgical m

Neuromas cause severe residual problems at long-term despite surgery

Pain, and disabilities after neuroma surgery, using patient reported outcome measurements (PROMs), were evaluated by QuickDASH and a specific Hand Questionnaire (HQ-8). The 69 responding individuals (response rate 61%; 59% women; 41% men; median follow up 51 months) reported high QuickDASH score, pain on load, cold sensitivity, ability to perform daily activities and sleeping difficulties. Individ

The molecular epidemiology of HIV-1 in Sweden 1996 to 2022, and the influence of migration from Ukraine

BackgroundThe global distribution of HIV-1 subtypes is evolving, which is reflected in the Swedish HIV cohort. The subtype HIV-1A6, which may be prone to developing resistance to cabotegravir, is the most common subtype in Ukraine.AimWe aimed to examine trends in HIV-1 subtype distribution in Sweden, with a special focus on HIV-1A6, and to describe the virology, demography and treatment of Ukraini