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The optimal operative protocol to accomplish CO2-EVAR resulting from a prospective interventional multicenter study

Objectives: Carbon dioxide (CO2) angiography for endovascular aortic repair (CO2-EVAR) is used to treat abdominal aortic aneurysms (AAAs), especially in patients with chronic kidney disease or allergy to iodinated contrast medium (ICM). However, some technical issues regarding the visualization of the lowest renal artery (LoRA) and the best quality image through angiographies performed from pigtai

Environmental, geographical and time-related impacts on avian malaria infections in native and introduced populations of house sparrows (Passer domesticus), a globally invasive species

Aim: The increasing spread of vector-borne diseases has resulted in severe health concerns for humans, domestic animals and wildlife, with changes in land use and the introduction of invasive species being among the main possible causes for this increase. We explored several ecological drivers potentially affecting the local prevalence and richness of avian malaria parasite lineages in native and

Impact of trigeminal nerve and/or olfactory nerve stimulation on activity of human brain regions involved in the perception of breathlessness

Breathlessness is a centrally processed symptom, as evidenced by activation of distinct brain regions such as the insular cortex and amygdala, during the anticipation and/or perception of breathlessness. Inhaled L-menthol or blowing cool air to the face/nose, both selective trigeminal nerve (TGN) stimulants, relieve breathlessness without concurrent improvements in physiological outcomes (e.g., br

Arterial stiffness and subclinical atherosclerosis in the coronary arteries at different stages of dysglycaemia

Aim: Our aim was to investigate in a large population-based cohort study whether increased arterial stiffness and subclinical atherosclerosis in the coronary arteries differ at different stages of dysglycaemia. Methods: Data were obtained from SCAPIS, a population-based cohort of participants 50–64 years. The study population of 9379 participants was categorised according to glycaemic status: norm

EULAR recommendations for the management of ANCA-associated vasculitis : 2022 update

Background: Since the publication of the EULAR recommendations for the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in 2016, several randomised clinical trials have been published that have the potential to change clinical care and support the need for an update. Methods: Using EULAR standardised operating procedures, the EULAR task force undertook a systema

Cognitive decline and risk of dementia in older adults after diagnosis of chronic obstructive pulmonary disease

Cognitive screening has been proposed for older adults diagnosed with chronic obstructive pulmonary disease (COPD). Therefore, we examined the change over time in cognitive function and the risk of incident dementia in older adults after COPD diagnosis. A sample of 3,982 participants from the population-based cohort study Good Aging in Skåne was followed for 19 years, and 317 incident COPD cases w

Reference equations for breathlessness during incremental cycle exercise testing

Background Exertional breathlessness is commonly assessed using incremental exercise testing (IET), but reference equations for breathlessness responses are lacking. We aimed to develop reference equations for breathlessness intensity during IET. Methods A retrospective, consecutive cohort study of adults undergoing IET was carried out in Sweden. Exclusion criteria included cardiac or respiratory

The gold standard program (GSP) for smoking cessation : a cohort study of its effectiveness among smokers with and without cancer

BACKGROUND: Smoking cessation treatment is an important prognostic factor for survival after a cancer diagnosis, especially for tobacco-related cancers. After being diagnosed with lung cancer, approximately 50% of patients continue smoking or frequently relapse after a quit attempt. Given the importance of smoking cessation treatment for cancer survivors, the objective was to compare the effective

Assessing erythroferrone and iron homeostasis in preeclamptic and normotensive pregnancies : A retrospective study

Introduction: Preeclampsia (PE) is a pregnancy-related disorder associated with maternal hypertension and placental dysfunction. A significant micronutrient during pregnancy is iron, which is important in cellular functions. While iron absorption increases in pregnancy, little is known about the exact mechanisms regulating maternal iron levels and transfer through the placenta in normal and compli

Low-level HIV viraemia during antiretroviral therapy : Longitudinal patterns and predictors of viral suppression

OBJECTIVES: Our objective was to characterize longitudinal patterns of viraemia and factors associated with viral suppression in people with HIV and low-level viraemia (LLV) during antiretroviral therapy (ART).METHODS: We included people with HIV in the EuResist Integrated Database with LLV following ART initiation after 2005. LLV was defined as two or more consecutive viral load (VL) measurements

Nanoscale X-ray Imaging of Composition and Ferroelastic Domains in Heterostructured Perovskite Nanowires : Implications for Optoelectronic Devices

Metal halide perovskites (MHPs) have garnered significant interest as promising candidates for nanoscale optoelectronic applications due to their excellent optical properties. Axially heterostructured CsPbBr3-CsPb(Br(1-x)Clx)3 nanowires can be produced by localized anion exchange of pregrown CsPbBr3 nanowires. However, characterizing such heterostructures with sufficient strain and real space reso

Fetal Aortic Isthmus and Descending Aorta

Doppler evaluation of the aortic isthmus, located between the left subclavian artery and the ductus arteriosus, can provide important information on fetal hemodynamic adaptation/deterioration related to intrauterine hypoxia. The aortic isthmus acts as a shunt deviating part of the blood flow from ductus arteriosus to the cranial circulation to maintain a normal oxygen delivery to the fetal brain.

Rates of Progression in Patients with Alzheimer’s Disease Depending on Apolipoprotein E Genotype and Concomitant Medications.

Background: The apolipoprotein E (APOE) ε4 allele is associated with higher cholesterol levels, and an increased risk of developing Alzheimer’s disease (AD) and amyloid-related imaging abnormalities after initiation of amyloid-modifying therapies. A worse cognitive response to cholinesterase inhibitor (ChEI) treatment and longitudinal outcome in APOE ε4-carriers has been observed. Based on these c

Diagnostic reliability of monitoring for premature atrial and ventricular complexes

Aims Short-term ambulatory electrocardiogram (ECG) monitoring is often used to assess premature atrial complex (PAC) and premature ventricular complex (PVC) frequency, but the diagnostic reliability is unknown. The objective of this study was to study the day-to-day variability of PAC and PVC frequency. Methods We used 14-day full-disclosure mobile cardiac telemetry recordings without atrial fibri

Exploratory rasch analysis of a static-99R clinical cohort assessment

Modern test theory supplements the more prevalent classic methods for assessing test properties. However, such an assessment of the commonly used sexual recidivism risk assessment instrument, Static-99R, has yet to be attempted. This study evaluated the psychometric properties of said instrument using Rasch analysis. The clinical cohort assessed consisted of individuals with mental disorders convi

Contextualizing supply chain risk governance in critical infrastructure sectors : insights from the Swedish food system

PurposeCritical infrastructure (CI) sectors and their resilience are vital for societies to function. In many countries, vital societal functions (VSFs) and CIs depend on inter-organizational and international supply chains (SCs) which combine public and private actors with often competing interests and unclear responsibilities that create discontents. While collaborative supply chain risk managem

Cross-border and Multi-modal Cold Chain Risk Assessment: Applying FMECA on a new Thai-Laos route

Cross-border multi-modal and railway transportation often faces different risks and problems creating delays, sometimes driven by technical or administrative discontents between countries. For cold supply chains, the risks of such delays get even more important to understand and handle, due to the perishable characteristics of the goods. While some previous research has dealt with risk assessment