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Plasma Protein Profile Associated With a Family History of Early-Onset Coronary Heart Disease

BACKGROUND: – Proteins linked to heritable coronary heart disease (CHD) could uncover new pathophysiological mechanisms of atherosclerosis. We report on the protein profile associated with a family history of early-onset CHD and whether the relation between proteins and coronary atherosclerotic burden differs according to family history status, as well as inferences from Mendelian randomization. M

Being done with “it” : forensic psychiatric patients’ experiences with the development and treatment for co-occurring substance use disorders and mental disorders

Background: Co-occurring substance use disorders, and mental disorders are associated with significant suffering, high risks of violent reoffending and relapse in both substance use and psychotic episodes. Treatment for co-occurring substance use disorders in forensic mental health settings would benefit from incorporating patients’ understanding of their disorders. Method: Using an interpretative

Sex differences in the prevalence and risk factors for aortic valve calcification in the general population

Background Aortic valve calcification (AVC) is a disease process driven by inflammation and lipid infiltration, serving as a precursor to aortic stenosis. While male sex has been implicated as a risk factor for AVC, sex-specific differences, particularly among younger individuals in the general population, are not well characterised. Methods The Swedish CArdioPulmonary BioImage Study was used, com

Monitoring time-to-detection of recurrent atrial fibrillation in patients with transient new-onset atrial fibrillation detected initially during hospitalization for noncardiac surgery or medical illness

Background Approximately one-third-of patients with transient new-onset atrial fibrillation (AF) during hospitalization for noncardiac surgery or medical illness will have recurrent AF within 1 year when assessed using two 14-day ECG monitors. The proportion of patients that would be diagnosed with recurrent AF with less monitoring is unknown. Methods We used data from a prospective cohort of part

A systematic review of measures of emotion regulation in forensic settings

Background: The study of emotion regulation (ER) has gained traction in forensic psychological and psychiatric research as a correlate of antisocial and aggressive behavior as well as for its relevance to psychopathology. However, conceptual and definitional ambiguity persists. Methods: This pre-registered systematic review aimed to investigate how ER is conceptualized and measured in forensic pop

European Code Against Cancer, 5th edition – outdoor and indoor air pollution and cancer

Most European Union (EU) residents live in areas where outdoor air pollution levels exceed the 2021 World Health Organization (WHO) air quality guidelines for fine particles and nitrogen dioxide. Outdoor air pollution is classified as carcinogenic to humans, and both outdoor and indoor air contain established human carcinogens, including diesel exhaust particulates, benzo(a)pyrene [B(A)P] and benz

European Code Against Cancer, 5th edition – occupational exposures and cancer

Occupational exposure to cancer-causing agents is a major, yet preventable, contributor to cancer in Europe and globally. In the European Union (EU), cancer is responsible for nearly half of all work-related deaths, underscoring the critical need for prevention measures. Effective strategies typically involve regulatory and workplace measures aimed at reducing or eliminating exposure risks. Raisin

European Code Against Cancer, 5th edition – ultraviolet radiation, radon and cancer

The European Code Against Cancer (ECAC) provides evidence-based recommendations to help individuals reduce their cancer risk. For the 5th edition (ECAC5), recommendations on ultraviolet radiation (UVR) and indoor radon exposures were updated, and complementary recommendations for policymakers were introduced. UVR and radon are classified as carcinogenic to humans (group 1 carcinogens) in the Inter

Agreement between ultrasonic bubble grades using a handheld self-positioning Doppler product and 2D cardiac ultrasound

(Plogmark O, Hjelte C, Ekström M, Frånberg O. Agreement between ultrasonic bubble grades using a handheld self-positioning Doppler product and 2D cardiac ultrasound. Diving and Hyperbaric Medicine. 2022 December 20;52(4):281−285. doi: 10.28920/dhm52.4.281-285. PMID: 36525686.) Introduction: Intravascular bubble load after decompression can be detected and scored using ultrasound techniques that me

Host shift and natural long-distance dispersal to an oceanic island of a host-specific parasite

Parasite dispersal and host-switching may be better understood by knowing when they occurred. We estimated when the ancestor of a parasite of great reed warblers (Acrocephalus arundinaceus) dispersed to the Seychelles and began infecting the endemic Seychelles warbler (A. sechellensis). We used mitochondrial genomes and published molecular divergence rates to estimate the date of divergence betwee

Longitudinal change in cerebro-placental ratio (CPR) between 37 and 40 weeks of pregnancy is associated with non-reassuring fetal status and increased risk of cesarean section

Objective: To evaluate in low-risk pregnancies if longitudinal change in cerebro-placental ratio (CPR) between 37 and 40 weeks of pregnancy is associated with cesarean section (CS) for non-reassuring fetal status (NRFS) during labor. Methods: This is a prospective observational study of women with singleton low-risk pregnancies who underwent an ultrasound scan at 36 + 0 to 37 + 6 and 39 + 0 to 41

Arterial stiffness and subclinical atherosclerosis in the coronary arteries at different stages of dysglycaemia

Aim: Our aim was to investigate in a large population-based cohort study whether increased arterial stiffness and subclinical atherosclerosis in the coronary arteries differ at different stages of dysglycaemia. Methods: Data were obtained from SCAPIS, a population-based cohort of participants 50–64 years. The study population of 9379 participants was categorised according to glycaemic status: norm

EULAR recommendations for the management of ANCA-associated vasculitis : 2022 update

Background: Since the publication of the EULAR recommendations for the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in 2016, several randomised clinical trials have been published that have the potential to change clinical care and support the need for an update. Methods: Using EULAR standardised operating procedures, the EULAR task force undertook a systema

Cognitive decline and risk of dementia in older adults after diagnosis of chronic obstructive pulmonary disease

Cognitive screening has been proposed for older adults diagnosed with chronic obstructive pulmonary disease (COPD). Therefore, we examined the change over time in cognitive function and the risk of incident dementia in older adults after COPD diagnosis. A sample of 3,982 participants from the population-based cohort study Good Aging in Skåne was followed for 19 years, and 317 incident COPD cases w