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Popular Abstract in Swedish Sedan kartläggningen av det mänskliga genomet, har mer fokus lagts på dess produkt, proteomet, som definieras som de proteiner som uttrycks i en cell vid en viss tidpunkt. Proteomets dynamiska egenskaper gör det till en fantastisk källa för så kallade biomarkörer, det vill säga molekyler som genom deras koncentrationsmönster kan användas för att särskilja sjuka och frisMultiplex protein quantification, proteomics, is essential for uncovering new biomarkers and understanding biology. Liquid chromatography coupled to mass spectrometry (LC-MS) is the predominant technique for these measurements. In this thesis, optimization and quality control strategies for different phases of the LC-MS pipeline have been developed. Due to the inherent complexity and dynamic rang

A simple analytical model for the link loss between two very low profile wireless body area network transceivers located at the same level on the human torso is presented. The model is based on the attenuation of the creeping waves on an elliptical approximation of the human torso. A good agreement between the model and the FDTD simulations on realistic heterogeneous phantoms of different age and

Scoliosis is an S-shaped sideways curvature of the spine leading to the shape change of the torso Idiopathic scoliosis is one form of this disease with unknown aetiology. 300 children out of 100 000 need treatment. Treatment duration is till the end of the patient’s growth age (till the ossification of the skeleton) and the brace should be worn 23 hours a day. Problems with brace are: heat, moist,

Popular Abstract in Swedish Partikelfysiken är studien av naturens minsta beståndsdelar --- De så kallade \emph{elementarpartiklarna}. All materia i universum består av elementarpartiklar. Den teori som beskriver vilka partiklar som finns och hur de uppför sig heter \emph{Standardmodellen}. Teorin har historiskt sett varit mycket framgångsrik. Den har gång på gång förutspått existensen av nya partThis thesis documents my work in the luminosity and supersymmetry groups of the ATLAS experiment at the Large Hadron Collider. The theory of supersymmetry and the concept of luminosity are introduced. The ATLAS experiment is described with special focus on a luminosity monitor called LUCID. A data-driven luminosity calibration method is presented and evaluated using the LUCID detector. This method

This paper presents three mathematical formulations for designing robust two-layer networks carrying elastic traffic. The formulations differ by the way flow reconfiguration is performed in the case of link failures. An iterative algorithm to solve the problems is given and an extensive numerical study is provided comparing the effectiveness of the three reconfiguration approaches. The formulation

The innovation process is a challenge for companies trying to achieve better outcomes through new ideas or products. The related literature discusses the importance of innovation as a learning process, underlined by a design perspective. Supported by design, the innovation process combines multidisciplinary aspects of creativity and dynamism, mainly for end-user oriented industries. For other indu

A highly optimized Monte Carlo (MC) code package for simulating light transport is developed on the latest graphics processing unit (GPU) built for general-purpose computing from NVIDIA - the Fermi GPU. In biomedical optics, the MC method is the gold standard approach for simulating light transport in biological tissue, both due to its accuracy and its flexibility in modelling realistic, heterogen

A uniplanar-compact electromagnetic band-gap (UC-EBG) structure is implemented at 60 GHz on a conventional PTFE (polytetrafluoroethylene) substrate. The structure surrounds a stacked microstrip antenna with gridded parasitic patch. The UC-EBG implementation results in about 5 dB decrease in the antenna E-plane normalized radiation pattern for angles along the substrate. The measured antenna gain i

The university programmes are basically nationally based, developed from the historical needs of specific need of a society. The Bologna process is challenging the educational market mainly at post-graduate level. The exchange of students is still limited to a reduced number of curious and ambitious persons, many with a high interest for cultural exchange – the ‘exotic dimension’. Individual caree

Although ethnic conflicts are an acute international problem, researchers in international relations have conducted surprisingly little research in this area. The aim with this study is to analyze one aspect of ethnic conflicts, how the elites representing ethnic groups act to make the great powers legitimize their own demands, and delegitimize the demands of the enemy by adducing to norms. In the

Plug-and-Produce (with the meaning that devices can be plugged in without any manual configurations needed) is an attractive paradigm for manufacturing systems, and in particular for Small and Medium Enterprises (SMEs) that do not have the expertise of system integrators but do need to be able to reconfigure their systems by themselves. One approach for loosely (in terms of timing) coupled devices

Summary of key messages for policy makers • Systemic approach is critical Climate change and natural resource depletion continues to be driven not least by unsustainable levels and patterns of consumption. There is growing recognition that the shift required to achieve sustainable consumption and production is a momentous paradigm shift in Western culture. Due to the holistic nature of shifting c

Antibody-based microarrays have emerged as an established proteomic technology allowing multiplexed and sensitive profiling of complex proteomes, in a high-throughput and miniaturized manner. Recently, numerous applicative efforts have been pursued generating disease-associated protein signatures that now could be further explored for improved disease diagnostics, prognostics and classification.

In the present study, different model order reduction methods were compared in terms of their effects on the dynamic characteristics of individual building components. A wide variety of methods were employed in two numerical examples, both being models of wooden floor structures, in order to draw conclusions regarding their relative efficiency when applied to models of such structures. It was obse