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The tourism sector has recommitted itself to be ‘climate neutral’ by 2050 through its 2021 Glasgow Declaration: A Commitment to a Decade of Tourism Climate Action. The declared ambition is consistent with the Paris Climate Agreement and net-zero emission targets; however, lacks specific actions by which such a transition might be achieved. The highly influential International Energy Agency (IEA) h
The fifth generation (5G) of mobile communications introduces improvements on many fronts when compared to its previous generations. Besides the performance enhancements and new advances in radio technologies, it also integrates other technological domains, such as cloud-to-things continuum and artificial intelligence. In this work, the 5G-DIVE Elastic Edge Platform (DEEP) is proposed as the linki
Phylogenetic reconstruction of cancer cell populations remains challenging. There is a particular lack of tools that deconvolve clones based on copy number aberration analyses of multiple tumor biopsies separated in time and space from the same patient. This has hampered investigations of tumors rich in aneuploidy but few point mutations, as in many childhood cancers and high-risk adult cancer. He
This report will discuss the influence of research into superfluid turbulence on my composition Der Rufer for percussion quartet. Written for Professor Olaf Tzschoppe, director of the Bremen Percussion Quartet, this work is the first result of a planned long-term collaboration with J.G. Weisend II, a Deputy Head of Accelerator Projects at the European Spallation Source (E.S.S.).
Äldreomsorgen är ett fält där det finns kolliderande rättigheter.Rätten till lika omsorg för alla kan vara svår att kombinera med kraven på ett förstå den enskildes behov och att erbjuda individanpassade insatser. Inte minst i frågan om rätten till att kunna utöva sin religion och leva enligt religiösa och kulturella traditioner på ett äldreboende ställs stora krav på både verksamheter och det lok
Many Gram-positive pathogenic bacteria employ ribosomal protection proteins (RPPs) to confer resistance to clinically important antibiotics. In Bacillus subtilis, the RPP VmlR confers resistance to lincomycin (Lnc) and the streptogramin A (SA) antibiotic virginiamycin M (VgM). VmlR is an ATP-binding cassette (ABC) protein of the F type, which, like other antibiotic resistance (ARE) ABCF proteins,
The stringent response is a global reprogramming of bacterial physiology that renders cells more tolerant to antibiotics and induces virulence gene expression in pathogens in response to stress. This process is driven by accumulation of the intracellular alarmone guanosine-5′-di(tri)phosphate-3′-diphosphate ((p)ppGpp), which is produced by enzymes of the RelA SpoT homologue (RSH) family. The Gram-
Identification of medical conditions using claims data is generally conducted with algorithms based on subject-matter knowledge. However, these claims-based algorithms (CBAs) are highly dependent on the knowledge level and not necessarily optimized for target conditions. We investigated whether machine learning methods can supplement researchers' knowledge of target conditions in building CBAs. Re
We have studied the accuracy of 16 different density functional theory methods to reproduce experimental data for bond lengths, angles, vibrational frequencies, as well as enthalpies and entropies for the binding of N2, H2, CO and hydride ions to various transition-metal complexes (with Fe, Ni, Cr, Mo andW) with relation to nitrogenase.We show that generalized gradient approximation functionals gi
Given the gaps between EU ambitions regarding energy community development and the current reality of clean energy communities in Europe, we explore a research framework enabling viable multi- and interdisciplinary research into new clean energy communities. We offer a definition of new clean energy communities, discuss their potential for wider dissemination and identify four factors that contrib
The over-arching aim of the access and benefit-sharing (ABS) of genetic resources is to enable fair distribution of benefits between the users (such as universities and biotech companies) and providers (such as biodiversity rich countries) so as to both open the doors for innovation and create incentives for biodiversity conservation. Access to genetic resources is crucial for research related to
An on-board measurement system has been developed that in real time identifies the probability for occurrence and also the exact location of severe wear in the wheelrail contact. Noise generated by the wheel-rail contact is a troublesome side effect both when railway vehicles negotiate curves and run on straight tracks. The concept behind this project is to use this noise as an indicator of the tr
Willow (Salix spp.) trees have been used commercially since the 1980s to produce renewable energy. Some benefits with these trees are that they can clean soil from heavy metals, reduce the risk of nutrient leakage and eutrophication. They could be an alternative to reduce carbon dioxide emissions from fossil fuel, but they are known to emit high rates of biogenic volatile organic compounds (BVOCs)
An economic model for determining the optimal automation level for discrete batch manufacturing is presented. The model describes how the costs of parts varies between manufacturing systems of different types at differing automation levels, the part costs often being highly dependent upon the automation level selected. The optimal automation level in a given case can be determined using a relative
Osteoarthritis (OA) is a leading cause of pain and disability which results in a reduced quality of life. Due to the avascular nature of cartilage, damaged cartilage has a finite capacity for healing or regeneration. To date, conservative management, including physical measures and pharmacological therapy are still the principal choices offered for OA patients. Joint arthroplasties or total replac
