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Objective: The concentration of the complex between activated protein C (APC) and protein C inhibitor (PCI) is a measure of thrombin generation. We studied whether it can provide information useful for the diagnosis and treatment of arterial vascular disease. Methods: Blood was obtained from 429 vascular patients admitted consecutively during September 2004 to March 2005. The APC-PCI complex was m
Introduction: Depression is frequent in ankylosing spondylitis (AS) patients. However, epidemiological data about the potential increase in risk are lacking. This study compares the rate of doctor-diagnosed depression in a well defined cohort of AS patients to the general population seeking care. Methods: The Skane Healthcare Register comprises healthcare data of each resident in Region Skane, Swe
The four-kallikrein panel and the Prostate Health Index (PHI) have been shown to improve prediction of prostate cancer (PCa) compared with prostate-specific antigen (PSA). No comparison of the four-kallikrein panel and PHI has been presented.
Genome-wide association (GWA) studies represent a powerful strategy for identifying susceptibility genes for complex diseases in human populations but results must be confirmed and replicated. Because of the close homology between mouse and human genomes, the mouse can be used to add evidence to genes suggested by human studies. We used the mouse quantitative trait loci (QTL) map to interpret resu
To determine benefits and harms of arthroscopic knee surgery involving partial meniscectomy, debridement, or both for middle aged or older patients with knee pain and degenerative knee disease.
Eumusc.net (http://www.eumusc.net) is a European project supported by the EU and European League Against Rheumatism to improve musculoskeletal care in Europe.
Background More effective prevention of suicide requires a comprehensive understanding of sociodemographic, psychiatric and somatic risk factors. Previous studies have been limited by incomplete ascertainment of these factors. We conducted the first study of this issue using sociodemographic and out-patient and in-patient health data for a national population. Method We used data from a national c
In young active adults with an acute anterior cruciate ligament (ACL) rupture, do patient reported or radiographic outcomes after five years differ between those treated with rehabilitation plus early ACL reconstruction and those treated with rehabilitation and optional delayed ACL reconstruction?
Boronic acid affinity gels are important for effective separation of biological active cis-diols, and are finding applications both in biotech industry and in biomedical research areas. To increase the efficacy of boronate affinity separation, it is interesting to introduce repeating boronic acid units in flexible polymer chains attached on solid materials. In this work, we synthesize polymer brus
Cluttering is a fundamental problem in 3D city model visualization. In this paper, a novel method for removing cluttering by typification of linear building groups is proposed. This method works. in static as well as dynamic visualization of 3D city models. The method starts by converting building models in higher Levels of Details (LoDs) into LoD1 with ground plan and height. Then the Minimum Spa
Intensity-modulated radiation therapy (IMRT) has during the recent years become a frequently used technique in radiotherapy. Lately IMRT has also been combined with rotational beam delivery, with a simultaneously moving couch, a technique called tomotherapy. The great benefit with this treatment method is the ability to give highly conformal treatments, with high dose to the tumour, while sparing
The controversy of the Swedish arms trade is expressed in the Swedish parliament as well as in the media. With the increase in arms trade profits, Sweden is in 2011 the country with the highest rate of arms trade per capita in the world. The core of the debate is the conflict between the national security interests, and human rights. Guidelines prohibit arms exports to countries in battle, in spit
Our thesis is a single-case study in which we try to answer the question: Why didn?t the lobbygroup Eurogroup for Animals get enough support for their demands in the latest regulation regarding transport of animals? As an example of their cooperation with their memberorganisations, we have chosen the Swedish organisation Djurens Rätt. Through interviews with key-persons involved in the process and
The production of fast pyrolysis bio-oil (FPBO) from secondary biomass is a promising technique for the production of liquid biofuels. However, the resulting FPBO is often viscous and chemically unstable, requiring significant upgrading while also being difficult to work with. To overcome this issue, FPBO can be hydrotreated using slurry hydrotreatment, which has a long history as a processing tec
Incomplete reporting of microscopy methods undermines transparency, reproducibility, and data reuse. Despite recent initiatives, comprehensive, broadly endorsed, and accessible reporting guidelines are still lacking. Here, we present a bare minimal microscopy reporting requirements checklist that integrates human- and machine-readable input to provide clear, actionable guidance for researchers, re
