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BACKGROUND: The clinically significant antigens of the Duffy (Fy [FY]) blood group system are expressed on the red cell form of the FY glycoprotein, a promiscuous chemokine receptor and also a receptor for malarial parasites. After the cloning of cDNA coding for FY glycoprotein, the molecular basis of the three major alleles (Fya/Fyb/Fy) has been established. Because of the mistyping of the silent
"Foreword: The durability of building materials, especially the corrosion of reinforcement in concrete structures, has been a main research area in Scandinavia during the last decades. Results from many laboratories in the Scandinavian countries, and outside of Scandinavia, indicate that there are certain relationships between the service life and different concrete parameters, such as the water/b
Low molecular weight protein tyrosine phosphatase (LMW-PTP) dimerizes in the phosphate-bound state in solution with a dissociation constant of K-d = 1.5(+/-0.1) mM and an off-rate on the order of 10(4) s(-1).H-1 and N-15 NMR chemical shifts identify the dimer interface, which is in excellent agreement with that observed in the crystal structure of the dimeric S19A mutant. Two tyrosine residues of
Sodium stearoyl-2 lactylate (SSL) lipid surfactant molecules specifically bind partially hydrolysed oat proteins in aqueous medium and significantly enhance the dispersion stability of oat cereal preparations. The proposed complexation is composition dependent and a greater understanding of the role of both oat proteins and lipid surfactant in the effect was gained with data from high performance
The cellular and molecular pathways initiated by traumatic brain injury (TBI) may compromise the function and structural integrity of mitochondria, thereby contributing to cerebral metabolic dysfunction and cell death. The extent to which TBI affects regional mitochondrial populations with respect to structure, function, and swelling was assessed 3 hours and 24 hours after lateral fluid-percussion
Background: ABO genotyping is complicated by the remarkable diversity at the ABO locus. Recombination or gene conversion between common alleles may lead to hybrids resulting in unexpected ABO phenotypes. Furthermore, numerous mutations associated with weak subgroups and nondeletional null alleles should be considered. All known ABO genotyping methods, however, risk incorrect phenotype predictions
The determination of elemental abundances plays an important role inunderstanding the atmospheric processes that lead to anomalies inspectra of chemically peculiar stars. Ongoing study of the HgMn star χ Lupi has defined much of the elemental abundance distribution but progress is dependent upon the availability and accuracy of the atomic data. Here we present experimentally determined wavelengths
The first ESR spectroscopic evidence of a bimolecular homolytic substitution (SH2) reaction in a 77 K solid phase was presented, where radicals were substituted for the CH3 group of methylsilane and methylgermane (CH3XD3, X = Si, Ge). The radicals were generated by in situ UV-photolysis of CD3I in the solid CH3XD3 in an ESR cavity at 77 K. Using the selectively deuterium labeled compounds, it was
In 1999, seven dark-bellied brent geese Branta bemicla bemicla were followed during spring migration from western Europe to Arctic Russia using satellite telemetry. For six of the birds we were also able to monitor their summer stay at the Taymyr Peninsula, and for five birds part of their autumn migration was recorded. In this article, we report on site use during summer and spring/autumn migrati
Inversion recovery (T-1) and microwave power saturation studies have been performed, between 4 and 25 K, on the EPR signal from the stable tyrosyl radical, Y-D(.), in photosystem II core complex preparations from higher plants. Measurements are reported from the dark stable S-1 and first turnover S-2 states of the photosystem catalytic Mn cluster and in two cryoprotectant regimes; sucrose and ethy
Studies were conducted to elucidate co-receptor spectrum and function of the inflammatory receptor, CMKLR1/ChemR23, which was recently identified as the receptor for the cystatin-like chemoattractant, TIG2, also named chemerin. An infection model was applied based on stably transfiected NP-2.CD4 host cells expressing various co-receptor constructs and exposed to panels of HIV-1, HIV-2 and SIV prim
BACKGROUND: Pin-site infection and pin loosening are complications that can cause discomfort to the patients. The purpose of present study was to evaluate pin-site infection, pain, and the use of medications using the XCaliber pin (Orthofix) with optimized thread and tip design, and the commonly used standard pin (Orthofix) during the procedure of hemicallotasis osteotomy (HCO). MATERIAL AND METHO
Cathepsin D is a lysosomal protease implicated in cancer metastasis. Its concentration in breast tumours has also been shown to be of prognostic importance, although to what extent this is subject to lymph node status, the use of adjuvant therapy and menopausal status has not been clearly evaluated. At a cut-off level of 45 pmol/mg protein (61% of the 623 samples were classified as high cathepsin
To compare gender-related normal limits for left ventricular (LV) ejection fraction (EF), end-diastolic and end-systolic volumes (EDV and ESV), obtained using two myocardial perfusion-gated single photon emission computed tomography (SPECT) quantification methods. A total of 185 patients were retrospectively selected from a consecutive series of patients examined for coronary artery disease (CAD)
Expressions for first-order induced electronic transition matrix elements are derived within the coupled-cluster response theory framework. When combined with electric-dipole and spin-orbit operators, these matrix elements allow the calculation of radiative transition probabilities between singlet ground and triplet excited states. An implementation employing an atomic mean-field representation of
Antibody inhibition and alpha6beta1 ligand binding experiments indicate that the egg integrin alpha6beta1 functions as a receptor for sperm during gamete fusion; yet, eggs null for the alpha6 integrin exhibit normal fertilization. Alternative integrins may be involved in sperm-egg binding and fusion and could compensate for the absence of alpha6beta1. Various beta1 integrins and alphav integrins a
