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An immunological capacitive biosensor for calpastatin was developed, optimized and applied for the analysis of meat extract samples. Anti-calpastatin antibody was immobilized on a gold electrode modified with a self-assembled monolayer of mercaptoundecanoic acid and Protein A from Staphylococcus aureus, and the obtained immunosensor was inserted as the working electrode in an electrochemical cell
The aetiology of benign prostatic hyperplasia (BPH) remains unclear. The objective of the present study was to test the insulin, oestradiol and metabolic syndrome hypotheses as promoters of BPH. The design was a risk factor analysis of BPH in which the total prostate gland volume was related to endocrine and anthropometric factors. The participants studied were 184 representative men, aged 72-76 y
In diffusion MRI (dMRI), images are sensitised to water diffusion by the application of magnetic field gradients. Cell membranes hinder the diffusional motion and thereby contribute to the contrast in dMRI. Thus, the diffusion of water molecules is used a probe of tissue microstructure. Data from dMRI is often analysed using diffusion tensor imaging (DTI), which yields image biomarkers that reflecIn diffusion MRI (dMRI), images are sensitised to water diffusion by the application of magnetic field gradients. Cell membranes hinder the diffusional motion and thereby contribute to the contrast in dMRI. Thus, the diffusion of water molecules is used a probe of tissue microstructure. Data from dMRI is often analysed using diffusion tensor imaging (DTI), which yields image biomarkers that reflec
Our research group on paediatric haematology is focused on bleeding- and coagulation disorders in children, in particular on haemophilia and venous thrombosis. Haemophilia A and B are hereditary, X chromosomal recessive bleeding disorders caused by deficiency or absence of coagulation factors VIII (FVIII) or IX (FIX) in the blood. The general aim of this part of the research program is to improve Our research group on paediatric haematology is focused on bleeding- and coagulation disorders in children, in particular on haemophilia and venous thrombosis. Haemophilia A and B are hereditary, X chromosomal recessive bleeding disorders caused by deficiency or absence of coagulation factors VIII (FVIII) or IX (FIX) in the blood. The general aim of this part of the research program is to improve
The Urban Systems and Dynamics group, led by Prof. Nik, advances the boundaries of Building Physics to explore the complex interactions between buildings, urban systems, and climate. Our research focuses on designing and optimizing strategies for buildings and urban systems (with a big focus on energy systems) that drive the sustainable urban transition and enhance the built environment's resilien
The Parallel Systems Division brings together three distinct research groups. The Mathematical Insights into Algorithms for Optimization (MIAO), Embedded Systems Design Laboratory and Lund University Graphics Group (LUGG).
The study of entrepreneurship has become one of the most popular fields of research in the area of management over the last few decades. New and small businesses are seen collectively by politicians and decision-makers as the main contributors to the development of the economy and wealth creation in society. Sten K. Johnson Centre for Entrepreneurship conducts internationally renowned research wit
A shift in new venture creation can be observed from purely profit-oriented models to alternatives attempting to also answer social and environmental needs. Because of their nature, these alternatives face issues regarding their integration in traditional financial and business spheres. Shared Value Creation is a framework that attempts to analyse these ventures and those challenges. Blockchain te
Background: Previous studies have suggested that targeting the site of latest mechanical activation of the left ventricle (LV) results in improved cardiac resynchronization therapy (CRT) outcomes. It is not known whether these benefits are sustained over medium-term follow-up. Objective: To assess the clinical outcome of imaging-guided LV lead position. Methods: We sought to assess the medium-term
BACKGROUND: Hospital readmissions are common among older multimorbid patients, and hospitalisation is associated with functional decline and reduced quality of life. Identifying patient characteristics and risk factors for repeated hospital visits following an emergency department (ED) encounter is important for guiding targeted interventions to prevent future revisits.AIM: To characterise multimo
The Middle East in the Contemporary World (MECW) is a multi- and transdisciplinary strategic research area, hosted and supported by the Center for Middle Eastern Studies, comprising staff from five different faculties at Lund University.
Background: For patients investigated with radiopharmaceuticals, it is important to be able to perform valid calculations of the absorbed dose in organs and tissues. An internal dosimetry computer program, IDAC-Dose2.1, has been updated to be based on the ICRP specific absorbed fractions and computational framework of internal dose assessment for 12 adult and paediatric reference individuals given
The Division of IT is Lund University’s central IT function. It supports the university’s digitalisation by providing efficient, high-quality IT support. The Division of IT comprises four operational departments and one staff department. The Division of IT is responsible for the operation and development of both software applications and IT infrastructure. Prior to 1 January 2024, the organisation
