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A series of recent studies have provided initial evidence about the role of specific intra-molecular interactions in maintaining proteins in their soluble state and in protecting them from aggregation. Here we show that the amino acid sequence of the protein monellin contains two aggregation-prone regions that are prevented from initiating aggregation by multiple non-covalent interactions that fav
Many scholars and philosophers inspired by Antiquity, have commented upon a transformation of lived religion and a changing picture and technology of the Self during Late Antiquity. The Nag Hammadi Library contains a diverse body of thought and it is here argued that these texts are found in the epicentre of Late Antique conversion of religion and Self, containing important illustrations of new em
In temperate regions, many vector-borne parasites maximise their transmission prospects by adjusting reproduction to seasonal cycles of host susceptibility and vector availability. Nevertheless, in these regions there are areas where environmental conditions are favourable throughout the year, so that parasites could benefit from a year-round transmission strategy. We analysed how different transm
Through genome-wide association meta-analyses of up to 133,010 individuals of European ancestry without diabetes, including individuals newly genotyped using the Metabochip, we have increased the number of confirmed loci influencing glycemic traits to 53, of which 33 also increase type 2 diabetes risk (q < 0.05). Loci influencing fasting insulin concentration showed association with lipid levels a
Few epidemiological studies have examined the association between dietary trans fatty acids and weight gain, and the evidence remains inconsistent. The main objective of the study was to investigate the prospective association between biomarker of industrial trans fatty acids and change in weight within the large study European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.
The health impact of dietary replacement of carbohydrates with protein for patients with type 2 diabetes is still debated. This study aimed to investigate the association between dietary substitution of carbohydrates with (animal and plant) protein and 5-year weight change, and all-cause and cardiovascular (CVD) mortality risk in patients with type 2 diabetes.
The purpose of this study is to compare the value of statistical life (VSL) estimates for traffic, drowning, and fire accidents. Using a choice experiment in a mail survey of 5,000 Swedish respondents we estimated the willingness to pay for risk reductions in the three accidents. In the experiment respondents were asked a series of questions, whether they would choose risk reducing investments whe
Background-Although metabolic risk factors are known to cluster in individuals who are prone to developing diabetes mellitus and cardiovascular disease, the underlying biological mechanisms remain poorly understood. Methods and Results-To identify pathways associated with cardiometabolic risk, we used liquid chromatography/mass spectrometry to determine the plasma concentrations of 45 distinct met
Among foreign-born women there is a significant employment gap compared to native women as well as foreign-born men. At the same time public institutions have been deemed as unable to deliver labor market integration efforts that are adapted to the needs of foreign-born women, which has been pointed out as a necessity. In this context, civil society-municipal partnerships have been recognized as a
Analys av hjältinnan utifrån ett feministiskt perspektiv. En jämförelse mellan Jane Austens hjältinna Elizabeth Bennet i Pride and Prejudice och Suzanne Collins hjältinna Katniss Everdeen i The Hunger Games.Analysis of the heroine from a feminist perspective. A comparison between Jane Austen's heroine Eliabeth Bennet in Pride and Prejudice and Suzanne Collins' heroine Katniss Everdeen in The Hunger Games.
This thesis deals with the enforcement of intellectual property rights as an abuse of dominance. In particular after refusal to license a patent, which is essential for a standardized technology. Seeking for injunction relief may in some circumstances violate applicable competition law. The analysis will provide a hint, whereas patent holder who is dominating in particular market can or should be
The role of the museum within society today is significantly different from how it used to be. The last five decades have seen an increase in focus on pedagogy, accessibility and outreaching activities within the museums, and it has had an effect on both how the museum is viewed from the public eye, as well as how the work within the organisations is carried out, by the increasing amount of differ
Today’s working life is becoming increasingly flexible, which is a consequence of and enabled by the technological development that is constantly affecting organizations around the world. According to a Swedish study from 2013 almost half (47 %) of the jobs on the Swedish labor market can be described as partly or even completely unregulated. But the question is whether this flexibility affects th
The aim of this study was to investigate how women reason about, and experience what it is like to live in Sweden in the months following the autumn of #metoo the year 2017. In utilizing interpretative phenomenological analysis (IPA) the accounts of three women can make an academic footprint in our society. Could a mostly digital aspect of a social movement influence how people think about themsel
Indonesia has a history of hundreds of years revolving around the racism against its 3% Chinese ethnic minority—who are also known as Tionghoa. This circumstance engenders the racial-social order that has been shaping the attitudes and behaviours of the Chinese, both individually and collectively, in social, cultural, and political realms. The Chinese have become self-controlled and self-regulated
Den här uppsatsen undersöker Europadomstolens praxis gällande utvisningar av personer som har begått brott, som hävdar att deras utvisning strider mot Artikel 8 av Europakonventionen. Uppsatsen undersöker hur domstolen har använt sig av den nationella beslutsprocessens kvalitet som ett argument för att komma fram till sin slutsats i sådana fall. Uppsatsen utgår från premissen att utvisningar som bThis thesis examines the practice of the European Court of Human Rights to decide expulsion cases implicating migrants with criminal record under Article 8 of the European Convention on Human Rights by use of process-based review. It departs from the premise that such expulsions do not violate absolute rights but constitute interferences with a qualified right, which allows for infringements neces
Uppsatsen syftar till att söka förståelse till varför tvister mellan fackförbund om vem som ska teckna kollektivavtal uppstår. Arbetsmarknadernas parter är i allmänhet ense om att det som regel bör finnas ett kollektivavtal på varje avtalsområde. Kollektivavtalets speciella rättsverkningar gör det viktigt för fackförbunden att vara avtalspart i ett kollektivavtal. Kollektivavtalet sätter i stor utThe aim of this essay is to seek understanding about why conflicts appear between trade unions regarding which one of them should sign the collective agreement in the workplace. The labour market parties are in general in an agreement that there should only be one applicable collective agreement in every area of work. The unique effects of the collective agreement make it crucial for the trade uni
