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Multimorbidity, i.e., two or more non-communicable diseases (NCDs), is an escalating challenge for society. Venous thromboembolism (VTE) is a common cardiovascular disease and it is unknown which multimorbidity clusters associates with VTE. Our aim was to examine the association between different common disease clusters of multimorbidity and VTE. The study is an extended (1997–2015) cross-sectiona
Solid-liquid interfaces are at the heart of a wide variety of phenomena. Their investigation requires experimental techniques with surface sensitivity such scanning probe microscopy and nonlinear optical techniques. In recent years, solid-liquid interfaces have been investigated with a novel approach based on the generation of high frequency acoustic and optical phonons. Due to the sensitivity of
The development of high-brilliance X-ray sources, such as the fourth-generation diffraction-limited storage rings and X-ray free-electron lasers, have opened up new possibilities for X-ray imaging and pushed the temporal resolutions of imaging techniques to unprecedented levels. Capturing fast dynamics in two-dimensional (2D), three-dimensional (3D), and even four-dimensional (4D, 3D + time) beyon
Quantum thermal machines can generate steady-state entanglement by harvesting spontaneous interactions with local environments. However, using minimal resources and control, the entanglement is typically weak. Here, we study entanglement generation in a two-qubit quantum thermal machine in the presence of a continuous feedback protocol. Each qubit is measured continuously and the outcomes are used
Background: Telomere length (TL) and mitochondrial function expressed as mitochondrial DNA copy number (mtDNAcn) are biomarkers of aging and oxidative stress and inflammation, respectively. Methylmercury (MeHg), a common pollutant in fish, induces oxidative stress. We hypothesized that elevated oxidative stress from exposure to MeHg decreases mtDNAcn and shortens TL. Methods: Study participants ar
Background and objective: We investigated whether adding 4Kscore as a reflex test to prostate-specific antigen (PSA) could improve the screening algorithm for prostate cancer (PC). Methods: In the GÖTEBORG-2 PC screening trial, 38 000men (50–60 yr) were invited to PSA testing and, if elevated, followed by magnetic resonance imaging (MRI). For 571 men with PSA ≥3.0 ng/ml and evaluable outcomes, 4Ks
Nano-scale chemical inhomogeneity in surface oxide films formed on a V- and N-containing martensite stainless steel and tempering heating induced changes are investigated by a combination of synchrotron- based hard X-ray Photoelectron emission spectroscopy (HAXPES) and microscopy (HAXPEEM) as well as microscopic X-ray absorption spectroscopy (μ-XAS) techniques. The results reveal the inhomogeneity
We explore the potential of nanocrystals (a term used equivalently to nanoparticles) as building blocks for nanomaterials, and the current advances and open challenges for fundamental science developments and applications. Nanocrystal assemblies are inherently multiscale, and the generation of revolutionary material properties requires a precise understanding of the relationship between structure
Background: The recent guidelines from the European Society of Cardiology recommends using high-sensitivity cardiac troponin (hs-cTn) in either 0/1-h or 0/2-h algorithms to identify or rule out acute myocardial infarction (AMI). Several studies have reported good diagnostic accuracy with both algorithms, but few have compared the algorithms directly. Objective: We aimed to compare the diagnostic a
Severe chronic rhinosinusitis with nasal polyposis (CRSwNP) is a disabling airway disease that significantly impacts patients’ lives through the severity of symptoms, the need for long-term medical treatment and the high risk of recurrence post-surgery. Biological agents targeting type 2 immune responses underlying the pathogenesis of CRSwNP have shown effectiveness in reducing polyp size and eosi
Fourteen guests from all over Europe and editors of Chemistry Europe journals met for two days to discuss trends and challenges in publishing and to get to know each other during networking breaks and a social evening. The third Chemistry Europe Early Career Researchers Meeting was held on invitation by the Chemistry Europe societies at the Wiley-VCH offices in Weinheim, Germany. It was a great su
BACKGROUND: Type 2 diabetes (T2D) is a major risk factor for carpal tunnel syndrome (CTS) and trigger finger (TF), but less is known regarding the risk of developing T2D after being diagnosed with CTS or TF. CTS and TF could be early signs of preclinical T2D, and early detection of T2D is crucial to prevent complications and morbidity. Therefore, we investigate the association between CTS/TF and T
Background/objectives: Patients with Alzheimer’s disease (AD) are at present treated with galantamine without actual knowledge of plasma concentration levels. The aim of this presentation is to analyse the relationship between galantamine plasma concentration, dose, demographics and body mass index (BMI). Methods: A total of 84 AD patients recruited at the Memory Clinic in Malmö, Sweden, treated w
Research on human emotions towards large carnivores is often based on self-reported emotions. This study aimed to investigate physiological and behavioral responses to feared animals among people who say that they are fearful or not fearful of brown bear and wolf. Participants were recruited to be bear fearful only (n=8), fearful of both bear and wolves (n=15), or fearful of neither carnivore (n=1
