Filetype
This thesis is based on nine papers, all concerned with parameter estimation. The thesis aims at solving problems related to real-world applications such as spectroscopy, DNA sequencing, and audio processing, using sparse modeling heuristics. For the problems considered in this thesis, one is not only concerned with finding the parameters in the signal model, but also to determine the number of si
Background: A panel of four kallikrein markers (total, free, and intact prostate-specific antigen [PSA] and human kallikrein-related peptidase 2 [hK2]) improves predictive accuracy for Gleason score ≥7 (high-grade) prostate cancer among men biopsied for elevated PSA. A four-kallikrein panel model was originally developed and validated by the Dutch center of the European Randomized Study of Screeni
Hematocrit (HCT) measurements of blood from patients, blood donors and athletes are routinely performed on a daily basis. These measurements are often performed in centralized hospital labs by whole blood analyzers, which leads to long time-to-result. On site measurements, based on centrifugation can be done, but these assays require manual handling, are slow and can just measure HCT in contrast t
Based on small to moderate effect sizes for the wide range of symptomatic treatments in osteoarthritis (OA), and on the heterogeneity of OA patients, treatment guidelines for OA have stressed the need for research on clinical predictors of response to different treatments. A meta-analysis to quantify the effect modified by the predictors using individual patient data (IPD) is suggested. The initia
Background: In 2007, the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) issued recommendations on diet, physical activity, and weight management for cancer prevention on the basis of the most comprehensive collection of available evidence. Objective: We investigated whether concordance with WCRF/AICR recommendations is related to risk of death. Design: The
Metal joining remains an essential yet challenging process in manufacturing, particularly for components with small dimensions, multiplex, delicate geometries, or dissimilar metals, where conventional joining methods can be insufficient. Here, we introduce Gas Actuated Bonding (GAB), a novel joining method that employs gaseous melting-point-depressant (MPD) agents to induce a diffusion-active stat
Abstract The aim of my paper is to highlight on two works of woman –writers in yiddish literature, The memoirs of Glikl Hamel (1645-1741) and the lightly disguised auto-biographical novel, Deborah, by Esther Singer-Kreitman (1891-1954).The paper also describes the growth of the writers in strictly religious, Jewish families, Glikl´s in Germany, Esther´s in Poland. Personal crisis were starting-poi
Syftet med uppsatsen är att utforska och behandla statschefers rätt till immunitet vid grova folkrättsbrott. Den centrala frågan för uppsatsen är om statschefer idag kan begå brott mot folkrätten och ändå beviljas straffrihet. Immunitet för statschefer har utvecklats ur immuniteten för stater, som är baserad på att varje stat är suverän och likställd med andra stater. Fram till mitten av nittonhuThe aim of this thesis is to explore the status of the immunity afforded to heads of state for serious international crimes. The central question asked is whether heads of state at the present time can commit international crimes and still be granted impunity. The concept of head of state immunity developed from immunity afforded to states and is based on the principles of state-sovereignty and e
Omfattande behandlingsforskning har visat att mindfulnessbaserade interventioner är effektiva för att minska lidande hos smärtpatienter. Hur detta kan förklaras är dock ännu inte klarlagt. I den här kvasiexperimentella studien ville vi undersöka sambandet mellan mindfulnessförmåga, experentiellt undvikande och smärtupplevelse. Mer specifikt ville vi ta reda på om experentiellt undvikande kunde förExtensive research has shown that mindfulness-based interventions are effective when it comes to reducing experiences of pain in patients with chronic pain. However, the mechanisms behind the effect have not yet been fully clarified. The aim of this quasi-experimental study was to examine the correlation between mindfulness skills, experiential avoidance and the experience of pain. More specifical
Det finns olika teorier kring vem som bevisbördan ska falla på inom tvistemål när det råder oenighet kring huruvida ett visst rättsfaktum ligger för handen. Bevissäkringsteorin är en av dessa. Bevissäkringsteorin innebär att bevisbördan läggs på den som har haft det lättast för att säkra bevisning. Mot bevissäkringsteorin konkurrerar de materiella bevisteorierna. Dessa teorier förespråkar att beviThere are different theories regarding who should carry the burden of proof within civil cases when there is controversy regarding whether or not a certain fact is at hand. The theory of securing evidence is one of these. The theory of securing evidence states that the burden of proof should be placed on whomever has an easier time of securing evidence. The material theories of evidence compete wi
