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Objectives: Readily accessible human pancreatic beta cells that are functionally close to primary adult beta cells are a crucial model to better understand human beta cell physiology and develop new treatments for diabetes. We here report the characterization of EndoC-βH5 cells, the latest in the EndoC-βH cell family. Methods: EndoC-βH5 cells were generated by integrative gene transfer of immortal

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_scientific_reports.pdf - 2026-07-13

The scarab beetle Osmoderma eremita and its larval predator, the click beetle Elater ferrugineus, are threatened saproxylic beetles regarded as indicators of the species-richness of insect fauna of hollow deciduous trees. Male O. eremita produce the pheromone (R)-(+)-gamma-decalactone to attract conspecific females, and this compound is also utilized by E. ferrugineus as a kairomone, presumably fo

BACKGROUND: Inversions involving intron 22 (Inv22) of F8 are detected in approximately 45% of all severe hemophilia A patients. Diagnosis is complicated by the large size of the ~9.5 kb int22h repeated sequence which generates the inversions. Methods such as long-range PCR and inverse-shifting PCR are currently used diagnostically, but suffer from low PCR efficiencies and are difficult to standard

Nano-LEDs, with sizes smaller than 1 μm and close to sub-wavelengths, have received increasing attention because of their potential applications in next-generation self-emissive displays, visible light communication, optogenetics, maskless lithography, on-chip super-resolution microscopy, etc. In contrast to the top-down fabrication of nano-LEDs, where the efficiency drop caused by dry-etching rel

Urinary tract infections (UTI) are the most common infectious diseases in the world. It is becoming increasingly tough to treat because of emergence of antibiotic resistance. So, there is an exigency to develop novel anti-virulence therapeutics to combat multi-drug resistance pathogenic strains. Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) discovery has revolutionized the gen

This paper focuses on the development of 2-terminal CIGS-perovskite tandem solar cells by exploring a range of stack sequences and synthetic procedures for depositing the associated layers. In the end, we converged at a stack sequence composed of SLG/Mo/CIGS/CdS/i-ZnO/ZnO:Al/NiO/PTAA/Perovskite/LiF/PCBM/SnO2/ITO. With this architecture, we reached performances only about 1% lower than the correspo

The paper presents novel studies on the electrical-to-thermal energy deposition to gas at different phases of a spark. The experiments utilized a 10.9 milliliter custom-built spark calorimeter. The energy transfer efficiencies across spark phases—breakdown+arc, and glow are quantified, emphasizing their importance in ensuring robust ignition. An AC capacitive ignition system was considered in the

Alternative fuels have been proposed as a means for future energy-secure and environmentally sustainable transportation. This review and benchmarking show that several of the alternative fuels (e.g. methanol, ethanol, higher alcohols, RME, HVO, DME, and biogas/CNG) work well with several different engine concepts such as conventional SI, DICI, and dual fuel, and with the emerging concepts HCCI, RC

LAMiNATE (Language Acquisition, Multilingualism, and Teaching) är en tvärdisciplinär och fakultetsöverskridande forskningsplattform som sammanför forskning och forskare vid LU med inriktning på (multimodal) språkinlärning, flerspråkighet, språkundervisning och språktestning och bedömning. LAMiNATE syftar till att stärka, möjliggöra och initiera samarbeten; utveckla nya, innovativa forskningsinriktLAMiNATE (Language Acquisition, Multilingualism, and Teaching) is a cross-disciplinary and interdepartmental research platform that brings together researchers at Lund University working on all areas of (multimodal) language acquisition, multilingualism, and language teaching/assessment. LAMiNATE aims to strengthen, facilitate, and initiate collaborations; to develop new innovative research strand