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The dendritic cell (DC) lineage encompasses a diverse population of cells with unique subtype-specific functions. In peripheral blood, four DC subsets have been identified based on their distinct expression of CD1c, CD141, CD16, and CD123, and these subpopulations exhibit functional properties in immune responses. However, their respective roles in allergic diseases, such as rhinitis, are unclear.
OBJECTIVES: Implementing environmental surveillance for poliovirus circulating from wastewater.METHODS: Six wastewater samples were collected from each final site within a wastewater collection system in Armenia, Quindío. Virus was extracted and concentrated by a method using polyethylenglycol and sodium chloride as concentrating agent. Polioviruses were identified by polymerase chain reaction ass
Production of propionic acid by fermentation of glycerol as a renewable resource has been suggested as a means for developing an environmentally-friendly route for this commodity chemical. However, in order to quantify the environmental benefits, life cycle assessment of the production, including raw materials, fermentation, upstream and downstream processing is required. The economic viability of
Smooth muscle cell (SMC)-specific deletion of transforming growth factor beta (TGF-beta) signaling would help elucidate the mechanisms through which TGF-beta signaling contributes to vascular development and disease. We attempted to generate mice with SMC-specific deletion of TGF-beta signaling by mating mice with a conditional ("floxed") allele for the type 11 TGF-beta receptor (tgfbr2(flox)) to
https://www.lu.se/evenemang/guided-tour-coin-cabinet - 2026-07-10
Abstract Due to the finite nature of fossil resources and their environmental impact, such as greenhouse gases and climate change, the bio-based production of chemicals, materials and fuels is the subject of extensive research in industrial biotechnology. Biotransformation and fermentation are considered to be mild, “green” processes that make use of effective and reliable biocatalysts to provide
Vår forskning fokuserar på personer med allvarlig och långvarig psykisk sjukdom och deras livssituation i samhället. De omfattande omstruktureringarna av det psykiatriska vård- och stödsystemet har inneburit långtgående krav på en utveckling av nya kunskapsbaserade vård- och stödinsatser. Detta för att främja hälsa och ett meningsfullt liv i samhället för den här gruppen och deras anhöriga. Många Our research focuses on individuals with severe and long-lasting mental illness and their situation in society. The extensive restructuring of the mental health and support systems towards community-based service systems brings forth far-reaching requirements for developing new knowledge-based health and support interventions. Such efforts are needed to favour and support health and a meaningful l
Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody preparations may trigger effects ranging from enhanced pro-inflammatory activity to increased anti-inflammatory activity. In contrast, reduction of IgG gly
Optical mapping by direct visualization of individual DNA molecules, stretched in nanochannels with sequence-specific fluorescent labeling, represents a promising tool for disease diagnostics and genomics. An important challenge for this technique is thermal motion of the DNA as it undergoes imaging; this blurs fluorescent patterns along the DNA and results in information loss. Correcting for this
