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Ptychographic Nano-Analytical Microscope (PtyNAMi) at PETRA III : Signal-to-background optimization for imaging with high sensitivity

The X-ray scanning microscope PtyNAMi at beamline P06 of PETRA III at DESY in Hamburg, Germany, is designed for high-spatial-resolution 3D imaging with high sensitivity. Besides optimizing the coherent ux density on the sample and the precision mechanics of the scanner, special care has been taken to reduce background signals on the detector. The optical path behind the sample is evacuated up unti

Cellular alterations identified in pluripotent stem cell-derived midbrain spheroids generated from a female patient with progressive external ophthalmoplegia and parkinsonism who carries a novel variation (p.Q811R) in the POLG1 gene

Variations in the POLG1 gene encoding the catalytic subunit of the mitochondrial DNA polymerase gamma, have recently been associated with Parkinson's disease (PD), especially in patients diagnosed with progressive external ophthalmoplegia (PEO). However, the majority of the studies reporting this association mainly focused on the genetic identification of the variation in POLG1 in PD patient prima

Circular RNAs to predict clinical outcome after cardiac arrest

Background: Cardiac arrest (CA) represents the third leading cause of death worldwide. Among patients resuscitated and admitted to hospital, death and severe neurological sequelae are frequent but difficult to predict. Blood biomarkers offer clinicians the potential to improve prognostication. Previous studies suggest that circulating non-coding RNAs constitute a reservoir of novel biomarkers. The

Clinical insights into small cell lung cancer : Tumor heterogeneity, diagnosis, therapy, and future directions

Small cell lung cancer (SCLC) is characterized by rapid growth and high metastatic capacity. It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority of SCLCs exhibit neuroendocrine features, an important subset of tumors lacks these properties. Genomic profiling of SCLC reveals genetic instability, almost universal inactivation of the tumor suppressor genes TP5

Comparison of four clinical risk scores in comatose patients after out-of-hospital cardiac arrest

Background and aims: Several different scoring systems for early risk stratification after out-of-hospital cardiac arrest have been developed, but few have been validated in large datasets. The aim of the present study was to compare the well-validated Out-of-hospital Cardiac Arrest (OHCA) and Cardiac Arrest Hospital Prognosis (CAHP)-scores to the less complex MIRACLE2- and Target Temperature Mana

Recommendations for Deprescribing of Medication in the Last Phase of Life : An International Delphi Study

Context: Medications may become inappropriate for patients in the last phase of life and may even compromise their quality of life. Objective: To find consensus on recommendations regarding deprescribing of medications for adult patients with a life expectancy of six months or less. Methods: Experts working in palliative care or other relevant disciplines were asked to participate in this internat

Familial risks in nervous system tumors

We used the nationwide Swedish Family-Cancer Database to analyze the risk for nervous system tumors in offspring through parental and sibling probands. Among 0-68-year-old offspring, close to 11000 patients with a nervous system tumor were identified in years 1961 to 2000, among whom 199 had a parent diagnosed with a nervous system tumor. Brain tumors constituted 86% of all tumors, and astrocytoma

Second primary cancers after sporadic and familial colorectal cancer

Second cancers were studied among 68,104 cases of colorectal cancer (CRC) from the Swedish Family-Cancer Database. A total of 1,113 patients received a diagnosis of second CRC; 25 of them had a family history of CRC. Cases of second CRC with a family history were diagnosed up to 10 years before sporadic cases. The relative risk (RR) of all second CRCs was 2.21 compared with the first CRC. Familial

Recurrence, fidelity and proximity to previously visited sites throughout the annual cycle in a trans-Saharan migrant, the common cuckoo

Most migratory birds return every year to the same breeding sites and some species show a similarly high fidelity to wintering grounds as well. Fidelity to stopover sites during migration has been much less studied and is usually found to be lower. Here, we investigate site fidelity and distance to previously visited sites throughout the annual cycle in the common cuckoo, a nocturnal trans-Saharan

The CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation

Background: The CTLA-4 blocking antibody ipilimumab has demonstrated substantial and durable effects in patients with melanoma. While CTLA-4 therapy, both as monotherapy and in combination with PD-1 targeting therapies, has great potential in many indications, the toxicities of the current treatment regimens may limit their use. Thus, there is a medical need for new CTLA-4 targeting therapies wit

Artificial intelligence together with mechanical imaging in mammography

Artificial intelligence (AI) applications are increasingly seeing use in breast imaging, particularly to assist in or automate the reading of mammograms. Another novel technique is mechanical imaging (MI) which estimates the relative stiffness of suspicious breast abnormalities by measuring the distribution of pressure on the compressed breast. This study investigates the feasibility of combining

GFAp and tau protein as predictors of neurological outcome after out-of-hospital cardiac arrest : A post hoc analysis of the COMACARE trial

Aim: To determine the ability of serum glial fibrillary acidic protein (GFAp) and tau protein to predict neurological outcome after out-of-hospital cardiac arrest (OHCA). Methods: We measured plasma concentrations of GFAp and tau of patients included in the previously published COMACARE trial (NCT02698917) on intensive care unit admission and at 24, 48, and 72 h after OHCA, and compared them to ne

GATA2 at the mitosis-to-G1 transition is critical for definitive hematopoiesis

In mitosis, transcription factors (TFs) and RNA polymerase disperse across the cytoplasm leading to transcriptional silencing, but some TFs are retained on condensed chromatin and mark genomic sites, a mechanism termed mitotic bookmarking. In pluripotent and differentiated cells this mechanism is important for pluripotency maintenance, cell reprogramming and lineage inheritance. However, the role

Expectations and Sensemaking : Older People and Care Robots

We do not yet know how the robotization of eldercare will unfold, but one thing is clear: technology mediates human practices and experiences [1]. As such, care robots will co-shape the actions of care givers and older people and influence the perceptions and experiences of old age. The robotization of eldercare means that it is essential for developers, policy makers, and researchers to become in

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Senast ändrad 1/10 2024 1 Litteratur och kunskap Nationell ämneskonferens i Lund 2–3/10 2024 ONSDAG 2/10 9.00–10.00 REGISTRERING, entréhallen, Språk- och litteraturcentrum 10.00–11.00 VÄLKOMST OCH KEYNOTE, sal 104 (hörsalen) 10.00–10.15 Konferenskommittén hälsar välkommen 10.15–11.00 Christian Benne (Köpenhamns universitet): No ledge. Thoughts on the poetics of knowledge 11.00–11.15 PAUS 11.15–12.

https://www.sol.lu.se/fileadmin/user_upload/sol/aemnen/sektion2/amneskonferens/KONFERENSSCHEMA_2024_%E2%80%93_rev._1_okt.pdf - 2026-05-16

Lungsjukdom avslöjas med nanopartiklar

Lungsjukdom avslöjas med nanopartiklar Hoppa till huvudinnehåll Vi använder cookies och andra spårningsteknologier för att förbättra användarupplevelsen på vår webbplats, för att visa dig personligt innehåll och riktade annonser och för att analysera vår webbplatstrafik. Läs mer om cookies. Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera och kan inte stängas

https://www.lth.se/article/lungsjukdom-avsloejas-med-nanopartiklar/ - 2026-05-16

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Department of Construction Sciences Solid Mechanics ISRN LUTFD2/TFHF10/5154-SE(1-54) ELASTO-PLASTICITY IN FEM INTEPERETED AS A DAE SYSTEM Master Thesis by Eric Borgqvist SUPERVISOR DOCENT MATHIAS WALLIN, DIV. OF SOLID MECHANICS EXAMINER PROF. MATTI RISTINMAA, DIV. OF SOLID MECHANICS Copyright c© 2010 by Div. of Solid Mechanics and Eric Borgqvist Printed by Media-Tryck, Lund ,Sweden For information

https://www.solid.lth.se/fileadmin/hallfasthetslara/utbildning/examensarbete/TFHF5154.pdf - 2026-05-16

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LUNDS UNIVERSITET Sida 1 av 8 HUMANISTISKA OCH TEOLOGISKA FAKULTETERNA PROTOKOLL Diarienummer STYR 2026/597 Sammanträdesdatum 2026-03-11 kl 09.15 -12.00 Fakultetsstyrelsens arbetsutskott Arbetsutskottets sammanträde 2026-03-11 Ledamöter Närvarande Anamaria Dutceac Segesten, universitetslektor, prodekan Alexander Maurits, universitetslektor, prodekan Johannes Persson, professor, dekanus, ordförande

https://www.ht.lu.se/fileadmin/user_upload/ht/dokument/Fakulteterna/protokoll/AU/Protokoll_AU260311_justerat.pdf - 2026-05-16