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A new Key Environmental Performance Indicators (KEPIs) approach has been developed considering the perspective of a designer who may like to improve the environmental performance of the products but has limited resources and understanding of complex environmental issues. This approach empowers the designer with indicators like the area of PWB, the amount of precious metals etc which account for th

The transmembrane protein Dystroglycan is a central element of the dystrophin-associated glycoprotein complex, which is involved in the pathogenesis of many forms of muscular dystrophy. Dystroglycan is a receptor for multiple extracellular matrix (ECM) molecules such as Laminin, agrin and perlecan, and plays a role in linking the ECM to the actin cytoskeleton; however, how these interactions are r

The rapid pace of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; COVID-19) pandemic presents challenges to the real-time collection of population-scale data to inform near-term public health needs as well as future investigations. We established the COronavirus Pandemic Epidemiology (COPE) consortium to address this unprecedented crisis on behalf of the epidemiology research comm

Background: Health-related quality of life (HRQoL) has been reported for out-hospital (OHCA) and in-hospital cardiac arrest (IHCA) separately, but potential differences between the two groups are unknown. The aim of this study is therefore to describe and compare HRQoL in patients surviving OHCA and IHCA. Methods: Patients ≥18 years with Cerebral Performance Category 1–3 included in the Swedish Re

In temperate regions, many vector-borne parasites maximise their transmission prospects by adjusting reproduction to seasonal cycles of host susceptibility and vector availability. Nevertheless, in these regions there are areas where environmental conditions are favourable throughout the year, so that parasites could benefit from a year-round transmission strategy. We analysed how different transm

The speed and intensity of modern sports puts the athlete at risk for impacts to the head, or to the body when the impact force is transmitted to the head. Rapid head rotation caused by these impact forces may lead to a sports-related concussion (SRC), defined as a mild traumatic brain injury, typically resulting in short-lived disturbance of the central nervous system function. The diagnosis of S

Health care is moving toward integrated services where care and rehabilitation are provided at home rather than in institutions. This, together with the requirement that care must be person-centered, has proven to be a considerable challenge. Older adults living with complex health conditions such as stroke are vulnerable to change when their responsibility for care and rehabilitation becomes exte

This paper presents a practical risk analysis method for critical, large-scale IT systems in an organisation. The method is based on reliability block diagram modelling and was adapted to fit the requirements of governmental organisations and to reduce the effort required to capture complex failure behaviour. Through the use of different failure categories the risk analysis can be simplified, the

Since the 1980’s, additive manufacturing (AM) has gradually advanced from rapid prototyping applications towards fabricating end consumer products. Many small companies may prefer accessing AM technologies through service providers offering production services as result-oriented Industrial Product-Service System (IPSS) rather than investing in their own production line. This study investigated pot