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Abstract in Norwegian Leukotriener syntetiseres fra arakidonsyre. De er potente proinflammatoriske mediatorer og bidrar til hyperreaktivitet i luftveiene. Antileukotriener er en ny gruppe medikamenter ved astma, og Zafirlukast, en leukotrienreseptorantagonist, er nå registrert for behandling av mild til moderat astma i Irland og Finland. Vi har foretatt en litteraturstudie vedrørende antileukotriLeucotrienes are synthesized from arachidonic acid. They are potent proinflammatory mediators that contribute to bronchial hyperreactivity. Antileukotrienes constitute a new group of antiasthmatic drugs. Zafirlucast, a leukotriene receptor antagonist, is now registered in Ireland and Finland for the treatment of mild to moderate asthma. We have studied the literature on antileukotrienes and have f

Investigation of turbulence models applied to premixed combustion using a level-set flamelet library approach

Most of the common modeling approaches to premixed combustion in engineering applications are either based on the assumption of infinitely fast chemistry or the flamelet assumption with simple chemistry. The level-set flamelet library approach (FLA) has shown great potential in predicting major species and heat release, as well as intermediate and minor species, where more simple models often fail

Studying the Stabilization Dynamics of Swirling Partially Premixed Flames by Proper Orthogonal Decomposition

Environmental regulations are continuously pushing lower emissions with an impact on the combustion process in gas turbines (GTs). As a consequence, GT combustors operate in very lean regimes (i. e., at relatively low temperature) to reduce NOx formation. Unfortunately, stabilization becomes a challenge for these lean premixed flames. The extremely unsteady dynamics of swirl stabilized flames pres

A Comparison of A Single and Multiphase Jets in a Crossflow Using LES

Large eddy simulations (LES) are performed for single and multiphase jets in crossflow (JICF). The multiphase JICF are compared to the single-phase case for the same momentum and mass flow ratios but with droplets of different sizes. Multiphase JICF have stronger counterrotating vortex pairs (CVPs) than a corresponding single-phase JICF. Moreover, their trajectories are higher and their induced wa