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We report on local nowcasting (short-term forecasting) of coronavirus disease (COVID-19) hospitalizations based on syndromic (symptom) data recorded in regular healthcare routines in Östergötland County (population ≈465,000), Sweden, early in the pandemic, when broad laboratory testing was unavailable. Daily nowcasts were supplied to the local healthcare management based on analyses of the time la

AimOur aim is to provide a-priori information on air-quality implications of potential future energy carriers in transportation relevant for sustainability, life cycle and health-impact assessments.MethodologyInformation on air- and climate-pollutant formation from energy carriers is collected in detailed laboratory assessments on heavy-duty combustion engines as well as on non-tailpipe emissions.

Precipitation is intrinsically associated with high uncertainty, which is exacerbated exponentially over time—especially concerning climate change. However, the current design practice in urban drainage infrastructure remains firmly bound to deterministic assumptions regarding the design load. This approach is too simplified—focusing only on the return period of the design event—and ignores the co

The discovery that the CRISPR/Cas9 system could be used for genome editing purposes represented a major breakthrough in the field. This advancement has notably facilitated the introduction or correction of disease-specific mutations in healthy or disease stem cell lines respectively; therefore, easing disease modeling studies in combination with differentiation protocols. For many years, variabili

Melanoma in advanced stages is one of the most aggressive tumors and the deadliest of skin cancers. To date, the histopathological staging focuses on tumor thickness, and clinical staging is a major estimate of the clinical behavior of primary melanoma. Here we report on an observational study with in‐depth molecular profiling at the protein level including post-translational modifications (PTMs)

Plasma analysis by mass spectrometry-based proteomics remains a challenge due to its large dynamic range of 10 orders in magnitude. We created a methodology for protein identification known as Wise MS Transfer (WiMT). Melanoma plasma samples from biobank archives were directly analyzed using simple sample preparation. WiMT is based on MS1 features between several MS runs together with custom prote

In this study, we demonstrate an acoustofluidic device that enables single-file focusing of submicron particles and bacteria using a two-dimensional (2D) acoustic standing wave. The device consists of a 100 μm × 100 μm square channel that supports 2D particle focusing in the channel center at an actuation frequency of 7.39 MHz. This higher actuation frequency compared with conventional bulk acoust

The recent advent of Optical Photothermal IR (O-PTIR), has enabled for the first time, submicron infrared microscopy in far-field reflection mode with the combination of Raman for simultaneous, correlative IR+Raman microscopy. These unique and exciting synergistic capabilities are now spawning interest in life science application. A broad range of life science applications, otherwise impossible wi

Background The influence of familial factors on the prognosis of heart failure (HF) is unknown. This nationwide follow‐up study aimed to determine familial mortality risks of HF among Swedish siblings hospitalized for HF. Methods and Results We linked several Swedish nationwide registers for individuals aged 0 to 80 years. The study population consisted of 373 people hospitalized for HF for the

AIMS: Cardiovascular disease (CVD) is one of the leading causes of mortality and morbidity worldwide, including in Sweden. The main aim of this study was to explore the temporal trends and spatial patterns of CVD in Sweden using spatial autocorrelation analyses.METHODS: The CVD admission rates between 2000 and 2010 throughout Sweden were entered as the input disease data for the analytic processes

The aim of this paper is to critically examine, discuss, draw conclusions, and come up with ideas how to harmonize GIS education in order to realize the envisaged clientele benefits globally. The paper draws experiences and lessons learnt, with examples from ongoing joint GIS MSc programs/courses being implemented in Mozambique, Rwanda, and Uganda. All the five courses (3 in Uganda, 1 in Mozambiqu

The Nordic countries offer an ideal case study of the COVID-19 pandemic due to their comparability, high data quality, and variable mitigations. We investigated the age- and sex-specific mortality patterns during 2020–2021 for the five Nordic countries and analysed the total age- and sex-adjusted excess deaths, ratios of actual to expected death rates, and age-standardized excess death estimates.

BACKGROUND: Chronic low-grade inflammation may play a role in the pathophysiology of depression, at least in a subset of patients. High-sensitivity C-reactive protein (hs-CRP) has been used to define an inflamed subgroup of depression with specific clinical characteristics and symptoms. In this study we investigated biochemical and clinical characteristics in patients with difficult-to-treat depre

Behandling av personuppgifter, vilket undersöks i denna uppsats, sker i den offentliga och privata sektorn, och i organisationer av alla storlekar. Personuppgiftsbehandlingar förekommer i varje gren av en organisation och hos alla olika aktörer, inom så spridda områden som rättsväsendet eller en frisörsalong. Mer specifikt syftar denna uppsats till att studera definitionen av "behandling"Personal data processing, as will be examined in this thesis, occurs in the public and the private sectors, in organisations of every size. It occurs in every branch of an organisation and by all different actors, be it law-enforcement or a hairdresser saloon. More specifically this thesis aims to study the definition of ‘processing’ and attempts to highlight the features and characterisation of i

Recent public opinion research and elite deliberation has established a particular interest in galvanizing an EU army to better enforce a sense of integration, stability and strengthin the Union. This article proposes an alternative mechanism, privileging Richard Rosecrance’s concept of the ‘virtual state’ as anequally important and worthyfactor contributing to all those aspects. The fourdefining

This paper aims at investigating the determinants of female farmers access to Agrarian Extension Services in Ethiopia, where extension services represent a critical tool for the development of the agrarian sector. Despite the country’s efforts to develop a gender-responsive extension system, several bottlenecks are negatively driving down women’s access to these services. By reviewing previous

Outcome under-ascertainment, characterized by the incomplete identification or reporting of cases, poses a substantial challenge in epidemiologic research. While capture-recapture methods can estimate unknown case numbers, their role in estimating exposure effects in observational studies is not well established. This paper presents an ascertainment probability weighting framework that integrates

Nowadays organisms encounter not only natural challenges from predators but also significant anthropogenic stressors, such as insecticides, which can profoundly disrupt their normal growth and behavior. However, the knowledge on their potential interactions remains largely unknown, particularly regarding how insecticides may affect predator-prey interactions and prey responses across multiple gene

List of scientific papers (peer-reviewed) scrutinized during the preparation of the synthesis Each article is assigned to at least one item in the three categories below. For some types of studies, e.g. reviews, observational or process studies, no item might be assigned in the third category, specifying the type of model applied. Subject of study: Atmospheric composition (ATC) – Bioenergy (BIE) –

https://www.cec.lu.se/sites/cec.lu.se/files/2020-11/e5_cec_synthesis_05.pdf - 2026-06-30