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Two monoclonal antibodies (mAb) CB268 and CII-C1 to type 11 collagen (CII) react with precisely the same conformational epitope constituted by the residues ARGLT on the three chains of the CII triple helix. The antibodies share structural similarity, with most differences in the complementarity determining region 3 of the heavy chain (HCDR3). The fine reactivity of these mAbs was investigated by s
In order to simplify and/or improve determination of glomerular filtration rate (GFR) the clearances of iohexol, 51Cr-EDTA and endogenous creatinine were simultaneously determined with different techniques in 21 anesthetized landrace pigs. Their GFR had been reduced to about 1/3 or less of normal GFR. After an intravenous bolus of the GFR markers, their plasma concentration curves were followed fo
We tested whether the "Lund" (LU) electrode-placement system compared to the Mason-Likar (M-L) electrode-placement system would produce waveforms more similar to those of standard electrocardiograms (ECGs) with regard to the QRS axis in the frontal plane and QRS changes of inferior myocardial infarction (MI). We also tested whether LU was more noise immune than standard, and whether the noise immu
OBJECTIVE: To describe the sonographic characteristic of squamous cell cancer (SCC) and adenocarcinoma (AC) of the cervix using transvaginal ultrasound. METHODS: Women with early stage cervical cancer undergoing transvaginal ultrasound examination prior to surgery were prospectively included. The sonographic characteristics were assessed with regard to tumor morphology, vascularization, size, exte
The direct scattering problem for an inhomogeneous lossy medium is examined for the one-dimensional case in which the phase velocity profile is discontinuous at the boundaries of the medium. Scattering operators (or impulse responses) and propagation operators are defined and equations that govern their behavior are developed. Knowledge of the scattering kernels for one round trip in the medium im
IL-5 is a Th2 cytokine which activates eosinophils and is suggested to have an atheroprotective role. Genetic variants in the IL5 locus have been associated with increased risk of CAD and ischemic stroke. In this study we aimed to identify genetic variants associated with IL-5 concentrations and apply a Mendelian randomisation approach to assess IL-5 levels for causal effect on intima-media thickn
Grass pea (Lathyrus sativus) is a leguminous food crop, grown mainly in the tropical and subtropical regions. It has valuable nutrients, however consumption of the seeds is reported to cause lathyrism, due to the presence of a non-protein amino acid (?-ODAP). The present study deals with the development of a process for reducing the ?-ODAP content in grass pea seeds. The consequences of processin
Research within contingency theory recognizes and postulates the relevance of contextual factors to the design of organizations. Thus organizations are dependent on the environments in which they operate and on the technologies they utilize. Organizations therefore need to process information about their environments and technologies. Information systems, including computerized information sytems,
Popular Abstract in Swedish Att bedöma välbefinnande hos patienter med mag/tarmcancer Avhandlingen handlar om undernäring, beroende/oberoende i det dagliga livet och uppfattningar om hälsorelaterad livskvalitet hos patienter som opereras pga cancer i mag/tarmkanalen. Enligt journaldokumentation hos 45 patienter som opererades 1985-89, för cancer i bukspottkörteln, hade patienterna ett försämrat nThe aim was to study some aspects of patients´ well-being, related to nutrition, activities of daily living and health related quality of life, when undergoing major gastrointestinal cancer surgery. Chart documentations (N=45) of patients undergoing subtotal pancreatectomy were studied, and showed the patients' well-being to be affected, although it was not possible to fully evaluate the results o
The use of polymers for the delivery of drugs has increased dramatically in the last decade. To ensure the desired properties and functionality of such substances, adequate characterization in terms of the molar mass (M) and size is essential. The aim of this study was to evaluate the changes in the M and size of PVP-b-PAMPS when the amounts of the synthesis reactants in the two-step radical react
AIM: To investigate the effects of a case management intervention for community-dwelling frail older people, with functional dependency and repeated contacts with the healthcare services, focusing on loneliness, depressive symptoms and life satisfaction.DESIGN: A two-armed, nonblinded, randomised control trial with repeated follow-ups, of N = 153 participants at baseline allocated to an interventi
OBJECTIVES: In this study, a systematic analysis was conducted of phasic intracoronary pressure and flow velocity in patients with severe aortic stenosis (AS) and coronary artery disease, undergoing transcatheter aortic valve replacement (TAVR), to determine how AS affects: 1) phasic coronary flow; 2) hyperemic coronary flow; and 3) the most common clinically used indices of coronary stenosis seve
A search is performed for localised excesses in dijet mass distributions of low-dijet-mass events produced in association with a high transverse energy photon. The search uses up to 79.8 fb−1 of LHC proton–proton collisions collected by the ATLAS experiment at a centre-of-mass energy of 13 TeV during 2015–2017. Two variants are presented: one which makes no jet flavour requirements and one which r
Background: The aim of this study is to evaluate the impact of lymphovascular space invasion (LVSI) on the risk of lymph node metastases and survival in endometrioid endometrial adenocarcinoma. Material and methods: As regard the study design, this is a cohort study based on prospectively recorded data. Patients with endometrioid endometrial adenocarcinoma registered in the Swedish Quality Registr
The title of our presentation refers to the collaborative dimensions of the Nordic Network for Music Education in professional development and knowledge development within our research field. This includes networking between senior and junior researchers, supervisors from different institutions, master students, Ph.D. students and the many discussions, challenging previous beliefs, that shape the
Low energy buildings are usually characterized by a very well insulated building envelope and an efficient ventilation system that makes use of the heat in the exhaust air. Internal heat gains from residents and their use of appliances can cover the heating demand to a certain extent. The magnitude of internal heat gains that cover demand are often modelled in a simplified way and thus can be asso
The problems of neutrino masses, matter-antimatter asymmetry, and dark matter could be successfully addressed by postulating right-handed neutrinos with Majorana masses below the electroweak scale. In this work, leptonic decays of W bosons extracted from 32.9 fb−1 to 36.1 fb−1 of 13 TeV proton–proton collisions at the LHC are used to search for heavy neutral leptons (HNLs) that are produced throug
Background: A long-term prospective observational safety study is essential to characterize fully the safety profile of systemic immunomodulating therapies for patients with atopic eczema. The TREatment of ATopic eczema (TREAT) Registry Taskforce offers a large platform to conduct such research using national registries that collect the same data using a predefined core dataset. Objectives: To pre
