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Objective. To investigate the occurrence of cardiovascular events (CVEs) in a large cohort of patients with antineutrophil cytoplasmic antibody (ANCA)-Associated vasculitis (AAV) across the European Union, China, Turkey, Russia, the United Kingdom, and the USA. Methods. Patients with a definite diagnosis of AAV who were followed for ? 3 months and had sufficient documentation were included. Data o
Objectives: Genome-wide association studies have revealed over 200 genetic susceptibility loci for prostate cancer (PCa). By combining them, polygenic risk scores (PRS) can be generated to predict risk of PCa. We summarize the published evidence and conduct meta-analyses of PRS as a predictor of PCa risk in Caucasian men. Patients and methods: Data were extracted from 59 studies, with 16 studies i
Two different factor V cDNA fragments were used as hydridization probes in the chromosomal assignment of the human and rat factor V genes. A 1.6-kb EcoRI fragment was used as a hybridization probe to analyze a panel of human-rodent somatic cell hybrids. Cosegregation of factor V specific DNA restriction fragments with human chromosome 1 was observed. In addition, a panel of rat-mouse somatic cell
By using a three dimensional computational method, gas flow and heat transfer have been investigated and analyzed for both cathode / anode ducts of proton exchange membrane fuel cells. The Brinkman- Forchheimer-extended Darcy model is employed to investigate the flow inside the porous layer of the duct. Effects of inertial coefficient, together with permeability, effective thermal conductivity, th
How human exposure levels of air pollutants are related to health status is an issue of great importance for e.g. infrastructural and urban planning. This study analysed the exposure levels of NO2 for individuals depending on their country of birth. The study was conducted within three different study areas of varying characteristics and extent to decide whether any such associations existed and i
