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Despite decades of research on the pathophysiology of depression, the development of new therapeutic interventions has been slow, and no biomarkers of treatment response have been clinically implemented. Several lines of evidence suggest that the clinical and biological heterogeneity among patients with major depressive disorder (MDD) has hampered progress in this field. MDD with low-grade inflamm
In 1934, Walter Benjamin published his major study Franz Kafka: Zur zehnten Wiederkehr seines Todestages. In the same year, Günther Anders, another German Jew in exile, gave a lecture on Kafka which later, in postwar years, developed into a small book titled Kafka, Pro und Contra. Bringing these two in dialogue—the much-celebrated essay by Benjamin and the generally overlooked book by Anders—the p
Famous for its many New Kingdom stelai and funerary shrines, Speos of Horemheb and magnificent quarries, this paper presents a preliminary report on a lesser acknowledged feature of Gebel el Silsila: its quarry marks. Focusing here on the northern section – Partition B – of Silsila East’s Main Quarry, seventeen individual quarry faces display totally 376 quarry marks, which have been divided into
In 2010, unmet medical care and sexual health counseling needs were assessed among students at a Ugandan University. Unmet medical care need was associated with poor mental health, experience of sexual coercion, and poor self-rated health. Unmet sexual health counseling need was significantly associated with being female, coming from an urban area, low social participation, poor mental health stat
A critical comparison of two mid 19th century versions of the story of As’ad al-Shidyâq, a young Maronite who became the first Protestant sympathiser in Lebanon; the first version written by an American missionary (Isaac Bird), the second by a Lebanese intellectual (Butrus al-Bustani) who became a Protestant. The comparison reveals differences between expatriate and indigenous perceptions of Prote
The IDEM3 maturity model is a process improvement framework that can be used by an organisation to assess and improve their IT dependability management processes. The framework focuses on the coordination of IT management and safety management within an organisation. In this paper, an evaluation plan for the maturity model is presented to evaluate its applicability, assessment accuracy, and practi
A flattening filter free x-ray beam mode was added to an Elekta linear accelerator by placing a flat copper plate in the filter carousel and recalibrating the electron steering servo, gun servo and dosimetry system. Machine configurations were saved onto a separate hard disk in order to remain separate from the clinical configuration. Profile measurements with a Schuster BMS diode array show that
Popular Abstract in Swedish Neuroblastom är den vanligaste solida tumören, utanför hjärnan, hos små barn och finns nästan inte alls hos vuxna. Varje år insjuknar mellan femton och tjugo barn i Sverige, de flesta före två års ålder. Överlevnaden har ökat de senaste tjugo åren men är fortfarande på låga nivåer för de mer aggressiva formerna. Neuroblastom uppstår i det sympatiska nervsystemet. DärförIn this thesis, the main focus has been on the childhood cancer neuroblastoma, one of the most common and lethal childhood tumours. Neuroblastoma has througout the years continued to be a clinical and biological enigma. Our first focus was on one of the most important biological risk factors in neuroblastoma -- amplification of the oncogene MYCN in the tumour cells. Because amplified MYCN typical
Popular Abstract in Swedish Antalet personer som är amputerade ovanför tålederna i Sverige kan uppskattas till mellan 5000 och 5500. (ca 0.06 % av befolkningen). Största delen av dessa är amputerade pg.a. av kärlsjukdom (≈ 80 %). Antalet årligen nytillkomna benamputerade i Sverige kan uppskattas till mellan 1000-1100 och mindre än 5 % av dessa fall är relaterade till andra orsaker, t.ex. trauma elThe current prevalence of persons amputated at transmetatarsal level or higher in Sweden can be estimated to be between 5000 and 5500 persons (approx. 0.06 % of the population). The majority of these are patients with vascular disease (≈ 80%). In Sweden between 1000 and1100 new amputees can be expect every year. Less than 5% of all amputations will be related to causes other than vascular disease.
An overview of current status and prospects of the development of quantum computer hardware based on inorganic crystals doped with rare-earth ions are presented. Major parts of the experimental work in this area have been done in two places, Canberra, Australia and Lund, Sweden, and the present description follows more closely the Lund work. Techniques will be described that include optimal filter
Popular Abstract in Swedish Tre-dimensionell ultraljudsundersökning av livmodertappen (cervix) Syftet med avhandlingen var att utvärdera förändringar i livmodertappen (cervix) med tre-dimensionellt ultraljud och utreda om tre-dimensionellt power Doppler ultraljud kan förutsäga tiden till spontan eller inducerad förlossning hos överburna, gravida kvinnor. Avhandlingen baseras på fem studier: reprThe aim of this thesis was to evaluate cervical physiological changes by three-dimensional (3D) ultrasound during pregnancy and to investigate the ability of 3D power Doppler to predict time to spontaneous and induced delivery in prolonged pregnancy. The thesis is based on five studies: reproducibility of cervical measurements by 3D power Doppler ultrasound (study I), reference data representativ
Popular Abstract in Swedish Prostatacancer är en mycket vanlig form av cancer, och det har visats att cirka hälften av alla män över 70 år har tumör i prostata. Prostatacancer är ofta en latent form av cancer, vilket innebär att den sällan ger kliniska symtom förrän i ett framskridet stadium. Sedan PSA testet började användas på 90-talet har antalet diagnostiserade fall av prostatacancer blivit alProstate cancer is currently the most common form of cancer in Sweden. Currently, the only biomarker used in the clinic is serum PSA, and there is a great need for new biomarkers that may increase the diagnostic and prognostic information so that better predictions can be made, and treatment may be tailored. Here, we have investigated two proposed biomarkers microseminoprotein-β (MSMB) and cystein
This article deals with multi-unit questioning turns used in different genres of institutional interactions. Analyzing in detail a corpus of about 400 multiunit questions from health care interactions, court trials, police interrogations, and social welfare office talks from Sweden and Finland (all in the Swedish language), a number of sequential patterns are established. Some of these sequential
We conducted a first pilot study on healthy women living in two countries with different dietary habits, Granada in the south of Spain and Malmo in the south of Sweden, in order to compare their levels of plasma phospholipid fatty acids, and to examine the relationship between the differences in food consumption. This study is part of a pilot study which is nested in the European Prospective Inves
The Energy using products (EuP) directive proposed by the European Commission is often referred to as "the first Integrated Product Policy (IPP) directive". The main purpose of the directive is to ensure the free movement of EuP in the internal market as well as to improve the environmental performance of products throughout their life cycle. Product groups likely to be addressed through the direc
Deviances in early event-related potential (ERP) components reXecting auditory and phonological processing are well-documented in children at familial risk for dyslexia. However, little is known about brain responses which index processing in other linguistic domains such as lexicon, semantics and syntax in this group. The present study investigated eVects of lexical-semantic priming in 20- and 24
