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The need for modelling of materials behaviour under various mechanical conditions is driven by the evolution of computer capacity and the ability of scientists to address complex mechanical problems. Reliable models for materials behaviour, including accurate numerical values of parameters, are necessary for a continued beneficial development of the computational side of solid mechanics. High rate

In "Intentional action and side-effects in ordinary language” (2003), Joshua Knobe reported an asymmetry in test subjects’ responses to a question about intentionality: subjects are more likely to judge that a side effect of an agent’s intended action is intentional if they think the side effect is morally bad than if they think it is morally good. This result has been taken to suggest that the co

This paper addresses the influence of deteriorating structural system characteristics on the value of structural health monitoring (SHM) before its implementation. The value of SHM is calculated within a recently developed framework utilizing the Bayesian pre-posterior decision analysis modelling the structural system performance, the integrity management, the structural risks and the SHM informat

Background: In Europe, residential care homes (RCHs) rather than hospitals are the most common care facilities for the older adult and the place where most deaths occur in this age group. There is a lack of knowledge regarding end-of-life (EOL) discussions and how they correlate with symptoms and symptom relief. Objective: The aim was to examine the correlation between EOL discussions and symptom

Introduction: Deliberate self-harm (DSH) is a common symptom in psychiatric disorders. It is a cross-diagnostic symptom, although it has mainly been associated with borderline personality disorder (BPD). Research has suggested an association between DSH and deficits in executive functioning. The main aim of the current study was to assess three specific aspects of executive functioning (EF) (worki

Artificial intelligence (AI) has been used to develop drug sensitivity prediction models, raising the opportunity of using it for personalized cancer medicine. This chapter describes recent advancements in drug response prediction methods using machine learning algorithms. Pharmacogenomic datasets come with different types of biological data including genetic mutations, gene expression, copy numbe

It is estimated that about 30 000 people a year are successfully resuscitated after having suffered an out-of-hospital cardiac arrest in Europe. The number of patients that are successfully resuscitated after an in-hospital cardiac arrest is not known, but it can be assumed that this figure is even higher than that after an out-of-hospital cardiac arrest. The aim of the Swedish Resuscitation Counc

Peptide synthesis was carried out in a variety of organic solvents with low contents of water. The enzyme was deposited on the support material, celite, from an aqueous buffer solution. After evaporation of the water the biocatalyst was suspended in the reaction mixtures. The chymotrypsin-catalyzed reaction between Z-Phe-OMe and Leu-NH2 was used as a model reaction. Under the conditions used ([Z-P

Proponents of religious non-doxasticism standardly aim to show how a commitment to traditional religion can be rational in the absence of religious belief. We demonstrate how the non-doxastic framework can be given a much wider application. In a study on Swedish semi-secularity, sociologist Ann af Burén has discovered a pattern where subjects simultaneously entertain naturalistic and supernatural

This article is devoted to a study of the Hardy space Hlog(Rd) introduced by Bonami, Grellier, and Ky. We present an alternative approach to their result relating the product of a function in the real Hardy space H1 and a function in BMO to distributions that belong to Hlog based on dyadic paraproducts. We also point out analogues of classical results of Hardy-Littlewood, Zygmund, and Stein for Hl

Through a systematic review and a series of meta-analyses, we evaluated the general responsiveness of putative transcriptional biomarkers of general toxicity and chemical stress. We targeted metal exposures performed on bivalves under controlled laboratory conditions, and selected six transcripts associated with general toxicity for evaluation: catalase (cat), glutathione-S-transferase (gst), heat

Infrared laser-induced grating spectroscopy (IR-LIGS) is a powerful method for the detection of molecules in atmospheric and combustion chemistry by exploiting their strong and species-specific fundamental vibrations. This work discusses potentials and limitations of the method.