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Professor Contact details Email: jan [dot] forsman [at] chem [dot] lu [dot] se Phone: +46 46 222 03 81Organisation Computational Chemistry Service point: 1 WebpageJan Forsmans profile in Lund University research portalOther affiliations Office director Computational Chemistry Member of Strategic Research Area eSSENCE: The e-Science CollaborationResearch areasDevelopments of approximate statistical
https://www.compchem.lu.se/jan-forsman - 2026-05-05
Studien undersökte beslutsfattandestilar enligt General Decision Making Styles Inventory – GDMS, (Scott & Bruce 1995), social önskvärdhet med Social Desirability Scale– MC-SDS, Mar-lowe and Crowne (1960), tvivel kring den egna bedömningsförmågan enligt Jugdmental Self-doubt Scale – JSDS, (Mirels et al., 2002), beslutsfattandedimensioner enligt Melbourne Decision Making Questionnare – MDMQ, (MaThe study investigated decision making styles according to the General Decision Making Styles Inventory – GDMS, (Scott & Bruce 1995) social desirability was measured with the Social De-sirability Scale– MC-SDS, Marlowe and Crowne (1960), judgmental self-doubt was measured with the Judgmental Self-doubt Scale – JSDS (Mirels et al., 2002), dimensions of decision making with the Melbourne Decisio
AIMS: To describe the level of physical activity 6 months after an out-of-hospital cardiac arrest (OHCA) and to explore potential risk factors of a low level of physical activity.METHODS: Post-hoc analyses of the international multicentre Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac arrest (TTM2) trial. At 6 months, survivors at 61 sites in Europe, Australia and
The antibody microarrays have become widespread, but their use for quantitative analyses in clinical samples has not yet been established. We investigated an immunoassay based on nanoporous silicon antibody microarrays for quantification of total prostate-specific-antigen (PSA) in 80 clinical plasma samples, and provide quantitative data from a duplex microarray assay that simultaneously quantifie
Human tumors xenografted in immunodeficient mice are crucial models in nuclear medicine to evaluate the effectiveness of candidate diagnostic and therapeutic compounds. However, little attention has been focused on the biological profile of the host model and its potential effects on the bio-distribution and tumor targeting of the tracer compound under study. We specifically investigated the dissi
MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate gene expression. There have been several reports of miRNA deregulation in prostate cancer and the biological evidence for an involvement of miRNAs in prostate tumorigenesis is increasing. In this study, we show that miR-34c is downregulated in prostate cancer (p = 0.0005) by performing qRT-PCR on 49 TURPs from prosta
Diamond-Blackfan anemia (DBA) is a congenital erythroid hypoplasia caused by haploinsufficiency of genes encoding ribosomal proteins (RPs). Perturbed ribosome biogenesis in DBA has been shown to induce a p53-mediated ribosomal stress response. However, the mechanisms of p53 activation and its relevance for the erythroid defect remain elusive. Previous studies have indicated that activation of p53
The transcription factor STAT3 is constitutively active in several malignancies including castration-resistant prostate cancer and has been identified as a promising therapeutic target. The fungal metabolite galiellalactone, a STAT3 signaling inhibitor, inhibits the growth, both in vitro and in vivo, of prostate cancer cells expressing active STAT3 and induces apoptosis of prostate cancer stem cel
Objective: To evaluate meat intake patterns in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohorts. Design and setting: 24-Hour dietary recalls were assessed within the framework of a prospective cohort study in 27 centres across 10 European countries by means of standardised computer-assisted interviews. Subjects: In total, 22 924 women and 13 031 men aged 35-74 years.
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is highly prevalent and causes serious health complications in individuals with and without type 2 diabetes (T2D). Early diagnosis of NAFLD is important, as this can help prevent irreversible damage to the liver and, ultimately, hepatocellular carcinomas. We sought to expand etiological understanding and develop a diagnostic tool for NAFLD usin
BACKGROUND: Gleason grading is the standard diagnostic method for prostate cancer and is essential for determining prognosis and treatment. The dearth of expert pathologists, the inter- and intraobserver variability, as well as the labour intensity of Gleason grading all necessitate the development of a user-friendly tool for robust standardisation.OBJECTIVE: To develop an artificial intelligence
Platinum(II) complexes of the type [Pt(thioether)2Cl]+(thioether = dimethyl sulfide, thioxane) are capable of abstracting a phenyl group from the BPh4 counterion with formation of trans[Pt(thioether)2ClPh] compounds. Thermal reactions proceed both in the solid phase and in nitromethane solution at elevated temperature and have preparative importance. Phenylation of the Pt(II) centre also occurs inPlatinum(II) complexes of the type [Pt(thioether)2Cl]+(thioether = dimethyl sulfide, thioxane) are capable of abstracting a phenyl group from the BPh4 counterion with formation of trans[Pt(thioether)2ClPh] compounds. Thermal reactions proceed both in the solid phase and in nitromethane solution at elevated temperature and have preparative importance. Phenylation of the Pt(II) centre also occurs in
Despite the recent success of tyrosine kinase inhibitors (TKIs) in the treatment of chronic myeloid leukemia (CML), approximately 2-17% of patients develop clonal cytogenetic changes in the Philadelphia-negative (Ph(-)) cell population. A fraction of these patients, in particular those displaying trisomy 8 or monosomy 7, are at risk of developing a myelodysplastic syndrome (MDS) or acute myeloid l
lunds universitet | samhällsvetenskapliga fakulteten | institutionen för strategisk kommunikation Kandidatprogram i Strategisk kommunikation och digitala medier Om programmet Programmet ger dig en bred baskompetens som kommunikatör med en inriktning mot digital kommunikation. Du lär dig grunderna inom public relations, marknadskommunikation och internkommu- nikation. Därtill läser du kurser som be
https://www.isk.lu.se/sites/isk.lu.se/files/sgsdm_16.pdf - 2026-05-06
lunds universitet | samhällsvetenskapliga fakulteten | institutionen för strategisk kommunikation Kandidatprogram i Strategisk kommunikation Om programmet Kandidatprogrammet i strategisk kommunikation är unikt i Sverige och erbjuder en utbildning med målet att du ska bli en ana- lytisk och praktiskt kunnig kommunikatör. Du tränas i kommunika- tionsteorier om till exempel varumärke, ledarskap, opin
https://www.isk.lu.se/sites/isk.lu.se/files/sgsko_16.pdf - 2026-05-06
Development of human hematopoietic stem cells and differentiation of embryonic stem (ES) cells/induced pluripotent stem (iPS) cells to hematopoietic stem cells are poorly understood. NOD (Non-obese diabetic)-derived mouse strains, such as NSG (NOD-Scid-il2Rg) or NRG (NOD-Rag1-il2Rg), are the best available models for studying the function of fetal and adult human hematopoietic cells as well as ES/
This work reports a method to select the optimal working frequency in transversal bulk resonator acoustophoretic devices by electrical impedance measurements. The impedance spectra of acoustophoretic devices are rich in spurious resonance peaks originating from different resonance modes in the system not directly related to the channel resonance, why direct measurement of the piezoelectric transdu
