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Neurodegeneration and inflammation are fundamental aspects of many neurological diseases. A genome-wide scan of the response to ventral root avulsion (VRA) in a rat F2 cross discloses specific gene regions that regulate these processes. Two gene loci displayed linkage to neurodegeneration and T cell infiltration, respectively, and a single locus displayed extreme linkage to VRA-induced major histo

Aims/hypothesis: Preterm birth (gestational age <37 weeks) has been associated with insulin resistance early in life. However, no large population-based studies have examined risks of type 1 and type 2 diabetes and potential sex-specific differences from childhood into adulthood. Clinicians will increasingly encounter adults who were born prematurely and will need to understand their long-term ris

OBJECTIVES: To evaluate knowledge translation after publication of the target temperature management 33°C versus 36°C after out-of-hospital cardiac arrest trial and associated patient outcomes. Our primary hypothesis was that target temperature management at 36°C was rapidly adopted in Australian and New Zealand ICUs. Secondary hypotheses were that temporal reductions in mortality would be seen an

Background The mortality in individuals with a family history of heart failure (HF) has not been determined. This nationwide sib-pair study aimed to determine mortality in individuals with a sibling affected with HF. Methods Sib-pairs were linked using the Swedish Multi-Generation Register, the Hospital Discharge Register and the Cause of Death Register for the period 1987–2012. Families with card

IntroductionAn important hallmark of cancer is escaping the immune system. Despite advances in immunotherapy, only a subset of patients experiences clinical benefits. It was shown that adoptive T cell or checkpoint inhibition therapy rely on the presence of conventional dendritic cells type 1 (cDC1). cDC1 excel in recruiting and priming protective CD8+ T cells through cross-presentation. However,

OBJECTIVE: To monitor serum concentrations of the aggrecan alanine-arginine-glycine-serine (ARGS) neoepitope in a clinical trial of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-5 inhibition as disease-modifying therapy of knee osteoarthritis, and to investigate relationships between reduction in ARGS and change in cartilage thickness, knee-related pain and function. DESITo monitor serum concentrations of the aggrecan alanine-arginine-glycine-serine (ARGS) neoepitope in a clinical trial of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-5 inhibition as disease-modifying therapy of knee osteoarthritis, and to investigate relationships between reduction in ARGS and change in cartilage thickness, knee-related pain and function.DesignROCCELLA t

IntroductionData regarding the impact of adenomyosis on the outcomes after in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) treatment are conflicting. Standardized diagnostic criteria are prerequisites for studying a potential association between adenomyosis and IVF/ICSI treatment outcomes. This study aims to examine the cumulative live birth rate (CLBR) after the first IVF/

Social services are adapting to an increasingly digital environment, with municipalities expectedto engage citizens through digital channels. This study investigates how clients seeking social as-sistance perceive and use digital tools as well as the challenges and opportunities that arise whenimplementing such technologies in line with public service values. The analysis draws on municipaldigitalSocial services are adapting to an increasingly digital environment, with municipalities expected to engage citizens through digital channels. This study investigates how clients seeking social assistance perceive and use digital tools as well as the challenges and opportunities that arise when implementing such technologies in line with public service values. The analysis draws on municipal digit

To broaden our understanding of bradyarrhythmias and conduction disease, we performed common variant genome-wide association analyses in up to 1.3 million individuals and rare variant burden testing in 460,000 individuals for sinus node dysfunction (SND), distal conduction disease (DCD) and pacemaker (PM) implantation. We identified 13, 31 and 21 common variant loci for SND, DCD and PM, respective

We describe the presumably first intentional ABO-incompatible deceased-donor kidney and pancreas transplantation with a severe antibody-mediated rejection during a rebound of isoagglutinins. Rejection was successfully treated with eculizumab, which inhibits the terminal pathway of complement. Complement analysis (C3, C3d,g, and a modified assay of classical complement-related hemolytic function) d

BACKGROUND: The period immediately following psychiatric inpatient care is recognized as a time of elevated risk of suicide, yet little is known about factors that influence how soon suicide occurs after discharge.AIM: To examine the timing of suicide among persons after psychiatric discharge and identify sociodemographic and clinical factors associated with a shorter time to death by suicide.METH

HbA1c as a time predictive biomarker for an additional islet autoantibody and type 1 diabetes in seroconverted TEDDY children OR I G I N A L A R T I C L E HbA1c as a time predictive biomarker for an additional islet autoantibody and type 1 diabetes in seroconverted TEDDY children Falastin Salami1 | Roy Tamura2 | Lu You2 | Åke Lernmark1 | Helena Elding Larsson1,3 | Markus Lundgren1,4 | Jeffrey Kris

https://www.teddy.lu.se/sites/teddy.lu.se/files/2023-03/144%20Salami_PedDiab_2022.pdf - 2026-05-25

Detecting potential outliers in longitudinal data with time-dependent covariates ARTICLE Detecting potential outliers in longitudinal data with time-dependent covariates Lazarus K. Mramba 1✉, Xiang Liu1, Kristian F. Lynch1, Jimin Yang 1, Carin Andrén Aronsson 2,3, Sandra Hummel4, Jill M. Norris5, Suvi M. Virtanen6,7,8,9, Leena Hakola8,9, Ulla M. Uusitalo 1 and Jeffrey P. Krischer1 © The Author(s),

https://www.teddy.lu.se/sites/teddy.lu.se/files/2024-04/162_MP286_Mramba_EJCN_2024.pdf - 2026-05-25

Plastic litter is a growing environmental problem. Recently, microplastics and nanoplastics, produced during breakdown processes in nature, have been in focus. Although there is a growing knowledge concerning microplastic, little is still known about the effect of nanoplastics. We have showed that mechanical breakdown of high-density polyethylene (HDPE), followed by filtration through 0.8 µm filte

Antibiotic resistance poses a global threat. Antibiotics are administered to 80-90% of terminally ill patients but evidence of their effectiveness in improving survival or symptom relief at the end of life (EOL) is scarce. To determine the proportion of deceased patients that continue antibiotic treatment after documented EOL discussion and the decision to prioritise symptom relief over active tre

Kista Mäss-service |www.kistamasservice.se | Phone +46(0)8- 506 65000 | email: kistamasservice@easyfairs.com Sida 1 (8) EXHIBITOR INFORMATION SACO STUDENT FAIRS 2025 T h o s e o f y o u t h a t u s e a n e x t e r n a l s t a n d b u i l d e r , p l e a s e f o r w a r d t h i s f o l l o w i n g i n f o r m a t i o n : VE NUE Kistamässan, Arne Beurlings Torg 5, 164 40 KISTA(visiting address) ORDE

https://www.saco.se/globalassets/bilder-video-och-dokument/studieval/saco-studentmassor/2025/exhibitor-information_saco_eng.pdf - 2026-04-14

Rightscities booklet A5 RIGHTSCITIES project brief The copyright of the RIGHTSCITIES Consortium Partners Publication design by Cornelia Walles Name of Authors: Hanna Johnsson, Cornelia Walles, Tatsiana Rahozina This booklet is part of the RIGHTSCITIES project, co- funded by the European Union, under the CERV-2023-CHAR-LITI call. Views and opinions expressed are however those of the author(s) only

https://rwi.lu.se/wp-content/uploads/2026/05/Rightscities-booklet-A5-5.pdf - 2026-05-23

Under sitt långa yrkesliv fick Hugo Fröderberg (1897–1986) följa utvecklingen av vad som då kallades ”sinnesslövården”. För eftervärlden kom han att bli känd som sjukhuschef och överläkare på Vipeholms sjukhus – Europas största i sitt slag med plats för nästan 1000 ”svårskötta, obildbara sinnesslöa”. Hugo Fröderberg föddes i Bäckaby i Fröderydsbygden mellan Vetlanda, Växjö och Värnamo, växte upp b

https://www.historiskamuseet.lu.se/vipeholm/vem-var-hugo-froderberg-och-vad-var-vipeholms-sjukhus - 2026-05-23

Lärande i LTH Detta fjärde blad från Genombrottet tar sin utgångspunkt i LTHs femte pedagogiska inspirationskonferens, varifrån fyra bidrag presenteras närmare. Numret innehåller också bl a information om kommande högskole- pedagogiska kurser och ett pedagogiskt lästips. Genombrottet, blad 4, december 2008 1 Genombrottet är LTHs pedagogiska stöd- och utvecklingsenhet som bl a ger högskolepedagogis

https://www.lth.se/fileadmin/cee/genombrottet/Laerande_i_LTH/Laerande_i_LTH_blad_4.pdf - 2026-05-24