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This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:- To assess the effect of preoperative alcohol cessation interventions on the rate of postoperative complications in hazardous drinkers- To assess the effect of preoperative alcohol cessation interventions for hazardous drinkers on alcohol use in the postoperative period and longer term
Notwithstanding its many successes since 1945, the project of European integration currently faces major difficulties, from financial crises and mass immigration to the impending departure of the UK from the European Union. At the same time, these challenges have spurred civil society organizations within and across Europe, revealing a shared public sphere in which citizens can mobilize around ref
We present a new way of performing hypothesis tests on scattering data, by means of a perturbatively calculable classifier. This classifier exploits the “history tree” of how the measured data point might have evolved out of any simpler (reconstructed) points along classical paths, while explicitly keeping quantum–mechanical interference effects by copiously employing complete leading-order matrix
This article examines the potential of digital welfare policies and practices to enhance the wellbeing of children in China, and the congruencies and contradictions of such policies with sustainable welfare. Can child welfare be supported digitally in ways that are not environmentally destructive? The rapidly diffusing concepts of digital welfare and sustainable welfare are presented, emphasising
Background: Coronary artery disease (CAD) is a leading cause of death worldwide and increasing cost for society. Genome wide association studies (GWAS) have identified common variants associated with CAD. Combining single nucleotide polymorphisms (SNPs) into a genetic risk score (GRS) can estimate an individual's genetic burden. Objectives: To investigate whether GRS for CAD can predict hospitaliz
The need for energy in water provision and use is obvious, however the drivers are often complex, difficult to assess, and often inconsistently presented. Here we build a clearer definition and conceptual framework of “water-related energy”. We apply this framework to harmonise data and results across disparate studies so that regional estimates of water-related energy can be compared in a consist
Sjukhusvistelser hos ett barn kan påverka hela familjen psykosocialt och praktiskt och många familjer föredrar vård i hemmet framför vård på sjukhus. Samtidigt varierar modeller för organisation, finansiering och genomförande av sjukvård i hemmet nationellt och internationellt och det kan vara svårt att överföra kunskap mellan länder och organisationer. Kunskapen om vad som är viktigt för att ge v
Peripheral nerve injuries are difficult to treat, and the clinical outcome after surgical repair and reconstruction is still insufficient, particularly concerning recovery of sensory function. To improve the clinical treatment strategies, experimental models are used to systematically examine the mechanisms behind nerve regeneration and assess the improvement of nerve regeneration by introduction
The importance of user-centric design methods in the design of programming tools is now well accepted. These methods depend on creating a feedback loop between the designers and their users, providing data about developers, their needs and behaviour gathered through various means. These include controlled experiments, field observations, as well as analytical frameworks. However, whilst there have
The maintenance of cell size homeostasis has been studied for years in different cellular systems. With the focus on ‘what regulates cell size’, the question ‘why cell size needs to be maintained’ has been largely overlooked. Recent evidence indicates that animal cells exhibit nonlinear cell size dependent growth rates and mitochondrial metabolism, which are maximal in intermediate sized cells wit
The biosynthesis of molecular species of phosphatidylethanolamine and phosphatidylcholine in isolated rat liver parenchymal cells was studied with [32P]phosphate and [3H]glycerol as precursors. Addition to the cells of albumin-bound oleic or linoleic acid resulted in the synthesis of high proportions of dioleoyl- or dilinoleoyl-phospholipids, especially from labeled glycerol. The fact that these s
Aims: Abdominal aortic aneurysm is a life-threatening condition due to the risk of aneurysm growth and rupture. There are no approved diagnostic or prognostic biomarkers for abdominal aortic aneurysm. We aimed to identify diagnostic and prognostic biomarkers for abdominal aortic aneurysm and to investigate their relationship with abdominal aortic aneurysm diameter and growth. Methods: In this case
Background: The substitution of bisphenol A (BPA) by bisphenol B (BPB), a very close structural analog, stresses the need to assess its potential endocrine properties.Objective: This analysis aimed to investigate whether BPB has endocrine disruptive properties in humans and in wildlife as defined by the World Health Organization (WHO) definition used in the regulatory field, that is, a) adverse ef
The first measurement of the Υ(1S) elliptic flow coefficient (v2) is performed at forward rapidity (2.5
