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Smoke propagation experiments in a real-scale residential building

An experimental study of smoke propagation from an apartment to an escape route corridor in a real-scale residential building is presented in this paper. The experiments were performed using the same experimental setup but with different ventilation and apartment door opening times. The setup consisted of a fire in a two-seater sofa in an apartment connected to a corridor and other apartments. A t

Thyroid autoimmunity and the subsequent development of islet and celiac autoimmunity in the TEDDY study

We aimed to determine if thyroid autoimmunity is associated with a child's risk for subsequent development of islet or celiac autoantibodies. Children at high genetic risk of type 1 diabetes were followed for thyroid autoimmunity (thyroid peroxidase antibodies [TPOAb] and thyroglobulin antibodies [TGAb]), islet autoimmunity (IA), and celiac disease autoimmunity [CDA] in The Environmental Determina

Chemical analysis of the Milky Way's nuclear star cluster : Evidence for a metallicity gradient

Context. The Milky Way nuclear star cluster (MWNSC) is located in the Galactic centre, together with the Milky Way nuclear stellar disc (MWNSD), and they dominate the gravitational potential within the inner 300 pc. However, the formation and evolution of the two systems and their possible connections are still under debate. Aims. We reanalysed the low-resolution KMOS spectra in the MWNSC with the

High resolution Ordovician (Floian-Sandbian) carbon isotope stratigraphy from the Jiangnan slope, South China : The first complete record of the MDICE in δ13Corg and its global significance

The Middle Darriwilian Isotopic Carbon Excursion (MDICE) is one of the globally recognized positive excursions in carbon isotope chemostratigraphy, but mainly documented by δ13Ccarb data in previous research. In this paper, new stable organic carbon isotope data (δ13Corg) are presented from the Hule-1 core from the southern Anhui Province of southern China. The core constitutes an Ordovician silic

Placement of Fast-Charging Infrastructure for Long-Haul Road Freight Based on Spatio-Temporal Evaluation of En-Route Energy Needs

The rapid progression of the electrification of road transport in many countries urges the need to make informed decisions on the location and size of the required charging infrastructure. This paper’s main contribution is a novel method to position fast-charging stations based on the transportation energy demand and to evaluate the performance of such charging infrastructure. Depending on their r

Sustainable Synthesis of Trimethylolpropane, a Biobased Polyol from Renewable Resources by an Integrated Process of Biotechnology and Chemical Reactions

Trimethylolpropane (TMP) is an important industrial chemical used to produce various value-added chemicals and polymers. In this study, both biobased butyraldehyde and formaldehyde were produced by the incomplete oxidation of bio-1-butanol and biomethanol, respectively, and were then used to produce a biobased TMP. High selective incomplete oxidation of primary alcohol to aldehyde is a challenging

Cryogenic Trapping Effects in GaN-HEMTs : Influences of Fe-Doped Buffer and Field Plates

This article investigates trapping mechanisms in AlGaN/GaN high electron mobility transistors (HEMTs) at cryogenic temperatures (CTs) down to 4.2 K, using pulsed I–V and drain current transient spectroscopy (DCTS) measurements. The results revealed an overall increase of trapping effects at CT. In particular, a substantial increase in current collapse at low temperatures was observed and predomina

Fatal and nonfatal sharp force injuries to the limbs : a study of forensic autopsies in Sweden (2010-2019)

BACKGROUND: Sharp force injuries display varying patterns depending on the manner of death (homicide, suicide, accidental). The purpose of this study was to analyse forensic autopsy data to examine the characteristics of sharp force injuries on the extremities, to differentiate between different manners of death and to examine demographic differences.METHODS: This retrospective cohort study utiliz

Proteomics discovery of MTDH and SND1 interaction vulnerabilities in ovarian cancer

High-grade serous ovarian cancer (HGSOC) is the most prevalent and aggressive subtype of ovarian cancer. The combination of late-stage diagnosis and the tendency to exhibit resistance to existing treatments highlights a critical gap in effective therapeutic options. There is thus a need for novel strategies for targeting HGSOC, particularly in its advanced stages. To address this gap, we developed

Energy Firm’s Financial Distress, Industry Shock and the Price of Oil and Gas Assets

A sample of 107 asset sales completed globally from October 2006 to January 2019 has been investigated to find the average discount at which the assets of distressed energy companies are liquidated. In the next step, the difference in difference approach has been used to explore the oil price crash in the fourth quarter of 2014 so as to find the difference in the average discount on the assets of

A population-based cohort study of KIR genes and genotypes in relation to cervical intraepithelial neoplasia

Natural killer (NK) cells are involved both in control of virus infections and in elimination of tumor cells. Killer immunoglobulin-like receptors (KIRs) either activate or inhibit NK cell-mediated cytolysis, protecting healthy cells from destruction while enabling killing of abnormal cells. To investigate whether KIR genes or genotypes are associated with cervical carcinogenesis, a nested case-co

Weight loss and body mass index in relation to aspiration in patients treated for head and neck cancer: a long-term follow-up

Persistent severe swallowing dysfunction with aspiration is a common and sometimes overlooked sequelae after treatment for squamous cell carcinoma of the head and neck (SCCHN) and may impact food intake and nutritional status. More knowledge is needed to increase the understanding of severe swallowing dysfunction as a risk factor for persistent nutritional deteriorations in SCCHN survivors. The pu

Scientific (wo)manpower - gender and the composition and earnings of PhDs in Sweden

Purpose - The purpose of this paper is to investigate to what extent male and female PhDs choose academic vs non-academic employment. Further, it analyses gender earnings differences in the academic and non-academic labour markets. Design/methodology/approach - Rich Swedish cross-sectional register data on the stock of PhDs in 2004 is used for investigating differences between male and female PhDs

Calcitonin gene-related peptide (CGRP) levels during glyceryl trinitrate (GTN)-induced headache in healthy volunteers

The role of nitric oxide (NO) in migraine has been studied in the experimental glyceryl trinitrate (GTN)-infusion headache model. We hypothesized that GTN-induced headache may activate the trigeminovascular system and be associated with increased levels of sensory neuropeptides, including calcitonin gene-related peptide (CGRP). CGRP, vasoactive intestinal peptide (VIP), neuropeptide Y (NPY) and so

The volume-expanding effects of autologous liquid stored plasma following hemorrhage.

Background: Plasma use has increased since studies have suggested that early treatment with blood components in trauma with severe hemorrhage may improve outcome. Plasma is also commonly used to correct coagulation disturbances in non-bleeding patients. Little is known about the effects of plasma transfusion on plasma volume. We report a prospective interventional study in which the plasma volume-

The impact of diabetes on coronary heart disease differs from that on ischaemic stroke with regard to the gender

Background: To study the diabetes related CVD risk between men and women of different ages. Methods: Hazards ratios (HRs) (95%CI) for acute CHD and ischaemic stroke events were estimated based on data of Finnish and Swedish cohorts of 5111 women and 4167 men. Results: 182 (3.6%) women and 348 (8.4%) men had CHD and 129 (2.5%) women and 137 (3.3%) men ischaemic stroke events. The multivariate adjus

Dependency of dinoflagellate vertical migration on salinity stratification

Increasing precipitation and surface water temperature due to global change may strengthen the salinity gradient in coastal regions, which could influence the behaviour of dinoflagellate migration. We studied diel vertical migration (DVM) behaviour in the dinoflagellates Prorocentrum minimum and Heterocapsa triquetra using vertically stratified laboratory columns with 3 different salinity gradient